P284TBT50

p16INK4a-TAT Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 P284TBT50-Each-of-1 In Stock ₹ 24,812.40

P284TBT50 - Each of 1

₹ 24,812.40

In Stock

Quantity

1

Base Price: ₹ 24,812.40

GST (18%): ₹ 4,466.232

Total Price: ₹ 29,278.632

Antigen

p16INK4a-TAT

Classification

Polyclonal

Conjugate

Biotin

Gene

CDKN2A

Gene Alias

p16INK4a

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1029

Content And Storage

-20°C

Applications

ELISA, Western Blot

Concentration

0.1-1.0 mg/mL

Formulation

PBS with no preservative

Gene Accession No.

P42771

Gene Symbols

CDKN2A

Immunogen

E.coli-derived, 18.0 kDa Recombinant Human p16-INK4a-TAT

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Form

Lyophilized

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Description

  • AA Sequence of recombinant protein: EPAAGSSMEP SADWLATAAA RGRVEEVRAL LEAGALPNAP NSYGRRPIQV MMMGSARVAE LLLLHGAEPN CADPATLTRP VHDAAREGFL DTLVVLHRAG ARLDVRDAWG RLPVDLAEEL GHRDVARYLR AAAGGTRGSN HARIDAAEGP SDIPDGYGR KKRRQRRR
  • Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human p16-INK4a-TAT
  • Anti-Human p16-INK4a-TAT-specific antibody was purified by affinity chromatography and then biotinylated
  • Sandwich ELISA: To detect Human p16-INK4a-TAT by sandwich ELISA (using 100 μL/well), a concentration of 0.25-1.0 μg/mL of this antibody is required
  • This biotinylated polyclonal antibody,in conjunction with PeproTech Polyclonal Anti-Human p16-INK4a-TAT (500-P284) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human p16-INK4a-TAT
  • Western Blot: To detect Human p16-INK4a-TAT by Western Blot analysis, this antibody can be used at a concentration of 0.1-0.2 μg/mL.When used in conjunction with compatible development reagents, the detection limit for Recombinant Human p16-INK4a-TAT is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions
  • 500-P284TBT-1MG will be provided as 2 x 500 μg p16-INK4a is a nuclear protein that regulates the cell cycle by inhibiting cyclin-dependent kinase-4 (CDK4) and CDK6
  • p16-INK4a inhibits CDK activity by binding to the CDK molecules in a manner that interferes with their ability to interact with cyclin D
  • This activity has the effect of suppressing tumor formation and growth, and of inducing replicative senescence in various normal cells, including stem cells
  • The expression of p16-INK4a steadily increases with age, and tends to accumulate in stem cell compartments
  • The deletion, rearrangement, or mutation of the p16-INK4a gene is frequently found in melanomas, as well as in certain other types of cancer
  • p16-INK4a and other transcription factors have been introduced into cells by DNA transfection, viral infection, or microinjection
  • Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other nuclear proteins into primary, as well as transformed, cells.

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Show Difference

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Fischer Scientific

P284TBT50

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Antigen:
p16INK4a-TAT

Classification:
Polyclonal

Conjugate:
Biotin

Gene:
CDKN2A

Gene Alias:
p16INK4a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
-20°C

Applications:
ELISA, Western Blot

Concentration:
0.1-1.0 mg/mL

Formulation:
PBS with no preservative

Gene Accession No.:
P42771

Gene Symbols:
CDKN2A

Immunogen:
E.coli-derived, 18.0 kDa Recombinant Human p16-INK4a-TAT

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Lyophilized

Img

Invitrogen™

P2858

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Vivid™ CYP450 Screening kits include Vivid™ CYP450 Fluorogenic substrates, BACULOSOMES™ CYP450 reagents, fluorescent standards, and an NADPH-regeneration system. Vivid™ CYP450 Fluorogenic substrates are also available separately. Store reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
300 Assays

Primary or Secondary:
__

Target Species:
__

Form:
__

Img

Thermo Scientific™

P2859

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
• Vivid™ CYP450 Fluorogenic substrates• BACULOSOMES™ CYP450 reagents• Fluorescent standards• NADPH-regeneration system.Vivid™ CYP450 Fluorogenic substrates are also available separately.Store reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
300 Assays

Primary or Secondary:
__

Target Species:
__

Form:
__

Img

Invitrogen™

P2860

--


Antigen:
__

Classification:
__

Conjugate:
__

Gene:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Gene ID (Entrez):
__

Content And Storage:
Vivid™ CYP450 Screening kits include Vivid™ CYP450 Fluorogenic substrates, BACULOSOMES™ CYP450 reagents, fluorescent standards, and an NADPH-regeneration system. Vivid™ CYP450 Fluorogenic substrates are also available separately. Store reaction buffers at +4°C or room temperature. Store BACULOSOMES™, the NADPH-regeneration system, and NADP+ at -80°C. Store the Vivid™ substrates and standards at +4°C, protected from light. (For long-term storage, resuspend in organic solvent and keep at -20°C.)

Applications:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
300 Assays

Primary or Secondary:
__

Target Species:
__

Form:
__