PA1754

BACE2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1754-Each-of-1 In Stock ₹ 48,084.72

PA1754 - Each of 1

₹ 48,084.72

In Stock

Quantity

1

Base Price: ₹ 48,084.72

GST (18%): ₹ 8,655.25

Total Price: ₹ 56,739.97

Antigen

BACE2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BACE2

Gene Alias

1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25825, 56175

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

Q9JL18, Q9Y5Z0

Gene Symbols

BACE2

Immunogen

Synthetic Peptide: C P(503) E V V N D E S S L V R H R W K(518)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-754 detects human and mouse beta-secretase 2 (BACE2) from transfected cells
  • This product has recently been remanufactured in new rabbits as Cat
  • # PA1-1754
  • PA1-754 has been successfully used in Western blot and ICC/IF procedures
  • By Western blot this antibody detects an ∽58 kDa protein representing BACE2 from SY-SY5Y cells overexpressing the human gene
  • The PA1-754 immunogen is amino acid residues 503-518 from human BACE2
  • This sequence is completely conserved in mouse
  • The PA1-754 immunizing peptide (Cat
  • # PEP-167) is available for use in neutralization and control experiments
  • BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP)
  • BACE2 cleaves APP between residues 690 and 691
  • This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP
  • BACE2 is also know to cleave APP between residues 671 and 672
  • Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients.

Compare Similar Items

Show Difference

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Thermo Scientific

PA1754

--


Antigen:
BACE2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BACE2

Gene Alias:
1110059C24Rik; 56 kDa aspartic-like protease; AEPLC; AI850424; ALP56; ARP1; asp 1; ASP1; ASP21; Aspartic-like protease 56 kDa; Aspartyl protease 1; Bace2; BAE2; be; beta secretase 2; Beta-secretase 2; beta-site amyloid beta A4 precursor protein-cleaving enzyme 2; beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; beta-site APP-cleaving enzyme 2; CDA13; CEAP1; Down region aspartic protease; Down syndrome region aspartic protease; DRAP; memapsin 1; memapsin-1; Membrane-associated aspartic protease 1; theta-secretase; transmembrane aspartic proteinase Asp1; UNQ418/PRO852

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25825, 56175

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q9JL18, Q9Y5Z0

Gene Symbols:
BACE2

Immunogen:
Synthetic Peptide: C P(503) E V V N D E S S L V R H R W K(518)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PA175447

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Antigen:
Testosterone

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
Androderm; C19H28O2; Mertestate; Sustanon; Testoderm; Testosteron

Host Species:
Sheep

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA

Concentration:
7.57 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Testosterone(17)-BSA

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG

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PA1758

--


Antigen:
Nicastrin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NCSTN

Gene Alias:
9430068N19Rik; AA727311; anterior pharynx-defective 2; Aph2; ATAG1874; D1Dau13e; Kiaa0253; mKIAA0253; NCSTN; Nct; Nicastrin; OTTHUMP00000031840; UNQ1874/PRO4317

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23385, 289231, 59287

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P57716, Q8CGU6, Q92542

Gene Symbols:
NCSTN

Immunogen:
Synthetic Peptide: C(688) I N A K A D V L F I A P R E P G A V S Y(708)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PA1761

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Antigen:
Phospho-AANAT (Thr29)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aanat

Gene Alias:
Aanat; AA-NAT; Aralkylamine N-acetyltransferase; arylakylamine N-acetyltransferase; Arylalkylamine N - acetyltransferase (Serotonin N - acetyltransferase); arylalkylamine N-acetyltransferase; DSPS; Nat-2; Nat4; Seretonin N-acetyltransferase; serotonin acetylase; Serotonin N-acetyltransferase; SNAT

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25120

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q64666

Gene Symbols:
Aanat

Immunogen:
Synthetic Peptide: C(24) Q R R H T(p) L P A S(33)

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG