PA1863

HDAC4 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA1863-Each-of-1 In Stock ₹ 44,705.10

PA1863 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HDAC4

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HDAC4

Gene Alias

4932408F19Rik; AHO3; AI047285; BDMR; DKFZp779K1053; HA6116; HD4; HD7; HD7b; HD9; HDAC; HDAC4; HDAC-4; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDACA; HDAC-A; HDRP; Histone deacetylase 4; histone deacetylase A; KIAA0288; KIAA0744; MITR

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

9759

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P56524

Gene Symbols

HDAC4

Immunogen

Synthetic peptide corresponding to residues M(1)SSQSHPDGLSGRDQPVE(18) of human HDAC4

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-863 detects histone deacetylase 4 (HDAC4) from human cells
  • PA1-863 has been successfully used in Western blot and ChIP procedures
  • By Western blot, this antibody detects an ∽140 kDa protein representing HDAC4 from HeLa cell lysate
  • An ∽110 kDa protein is also detected with PA1-863 which could correspond to protein degradation product
  • PA1-863 immunogen is a synthetic peptide corresponding to residues M(1)SSQSHPDGLSGRDQPVE(18) of human HDAC4
  • PA1-863 can be used with blocking peptide PEP-141 and blocking peptide PEP-095
  • Histone deacetylase 4 (HDAC4) is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4)
  • Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events
  • Histone deacetylases act via the formation of large multiprotein complexes
  • HDAC4 is also involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D
  • It is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer
  • Mutations to the HDAC4 gene have been found in Brachydactyly-mental retardation syndrome (BDMR).

Compare Similar Items

Show Difference

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Thermo Scientific

PA1863

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Antigen:
HDAC4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HDAC4

Gene Alias:
4932408F19Rik; AHO3; AI047285; BDMR; DKFZp779K1053; HA6116; HD4; HD7; HD7b; HD9; HDAC; HDAC4; HDAC-4; HDAC7; HDAC7B; HDAC9; HDAC9B; HDAC9FL; HDACA; HDAC-A; HDRP; Histone deacetylase 4; histone deacetylase A; KIAA0288; KIAA0744; MITR

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9759

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P56524

Gene Symbols:
HDAC4

Immunogen:
Synthetic peptide corresponding to residues M(1)SSQSHPDGLSGRDQPVE(18) of human HDAC4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PA186558

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Antigen:
Phospho-NMDAR2B (Tyr1472)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRIN2B

Gene Alias:
AW490526; EIEE27; GluN2B; GluRepsilon2; glutamate [NMDA] receptor subunit epsilon-2; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor; glutamate receptor ionotropic, NMDA 2B; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, NMDA2B; glutamate receptor, ionotropic, NMDA2B (epsilon 2); glutamate receptor, ionotropic, N-methyl D-aspartate 2B; GRIN 2B; GRIN2B; HGNC:4586; hNR 3; hNR3; LOW QUALITY PROTEIN: glutamate receptor ionotropic, NMDA 2B; MGC142178; MGC142180; MRD6; Nmdar2b; NMDE2; NME2; N-methyl D-aspartate receptor 2B; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 2B; N-methyl-D-aspartate receptor subunit 3; NR2B; NR3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.01% BSA, 50% glycerol and 0.09% sodium azide; pH 7.5

Gene Accession No.:
Q00960

Gene Symbols:
GRIN2B

Immunogen:
Synthetic phosphopeptide corresponding to an amino acid sequence within the NR2B subunit of the NMDA receptor, which includes phosphorylated Tyr1472.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

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PA186602

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Antigen:
alpha/beta Tubulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUBB1

Gene Alias:
2810484G07Rik; Alpha-tubulin 1; Alpha-tubulin 3; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; beta 5-tubulin; beta Ib tubulin; CDCBM6; CSCSC1; Detyrosinated tubulin alpha-1A chain; FLJ30169; H2 ALPHA; hum-a-tub1; hum-a-tub2; LIS3; M(beta)1; M40; OK/SW-cl.56; Talpha1 alpha-tubulin; Tuba1; Tuba-1; TUBA1A; TUBA3; TUBB; TUBB1; TUBB2A; TUBB5; Tubulin alpha; tubulin alpha 1a; tubulin alpha 3; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-3 chain; Tubulin B-alpha-1; tubulin beta; tubulin beta 1 class VI; tubulin beta chain; tubulin beta class I; tubulin beta-1 chain; Tubulin beta-5 chain; tubulin, alpha 1; tubulin, alpha 1A; tubulin, alpha, brain-specific; tubulin, beta 1 class VI; tubulin, beta 2A class IIa; tubulin, beta class I; tubulin, beta family 1; tubulin, beta polypeptide; a/β-tubulin

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100134983, 100135051, 203068, 22142, 545486, 64158, 679312, 733686, 7846, 81027

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
A2AQ07, P02550, P07437, P68369, P68370, Q71U36, Q767L7, Q9H4B7

Gene Symbols:
TUBA1A, TUBB, TUBB1

Immunogen:
Purified porcine brain tubulin.

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

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PA186695

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Antigen:
Rat Albumin

Classification:
Polyclonal

Conjugate:
FITC

Gene:
Alb

Gene Alias:
Alb; ALB protein; Alb1; albumin; Albza; Bos d 6; bovine serum albumin; BSA; Serum albumin

Host Species:
Sheep

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
24186, 280717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P02769, P02770

Gene Symbols:
Alb

Immunogen:
Native protein.

Quantity:
1 mg

Primary or Secondary:
Primary

Target Species:
Bovine, Rat

Product Type:
Antibody

Isotype:
IgG