PA540153

Phospho-Histone H2A.X (Tyr142) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA540153-Each-of-1 In Stock ₹ 45,218.46

PA540153 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

Phospho-Histone H2A.X (Tyr142)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

H2AX

Gene Alias

AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

15270, 3014, 500987

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P16104, P27661

Gene Symbols

H2AX

Immunogen

Peptide sequence around phosphorylation site of tyrosine 142(A-S-Q-E-Y(p)) derived from Human Histone H2A.X.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PA540152

--

Img

Thermo Scientific

PA540280

--

Img

Thermo Scientific

PA548429

--

Img

Thermo Scientific

PA540238

--

Img

Thermo Scientific

PA540265

--

Img

Thermo Scientific

PA540263

--

Img

Thermo Scientific

PA540200

--

Img

Thermo Scientific

PA540214

--

Description

  • This antibody is predicted to react with mouse and rat based on sequence homology
  • Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
  • In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
  • The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
  • The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
  • Structurally, H2A.x contains 143 amino acid residues
  • Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
  • There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
  • The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
  • Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
  • Histone H2A.x contributes to histone-formation and therefore the structure of DNA
  • Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA540153

--


Antigen:
Phospho-Histone H2A.X (Tyr142)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2AX

Gene Alias:
AW228881; gamma H2AX; gammaH2ax; H2A histone family member X; H2A histone family, member X; H2A.X; H2A.X variant histone; H2A/X; h2afx; H2ax; H2AX histone; Hist5-2ax; histone 5 protein 2ax; histone H2A.x; Histone H2a/x; Histone H2AX; RGD1566119; similar to H2A histone family, member X; zgc:56329

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15270, 3014, 500987

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P16104, P27661

Gene Symbols:
H2AX

Immunogen:
Peptide sequence around phosphorylation site of tyrosine 142(A-S-Q-E-Y(p)) derived from Human Histone H2A.X.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540154

--


Antigen:
Phospho-Histone H2B (Ser14)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2BC5

Gene Alias:
2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B clustered histone 1; H2B clustered histone 15; H2B clustered histone 17; H2B clustered histone 19; H2B clustered histone 2, pseudogene; H2B clustered histone 21; H2B clustered histone 5; H2B clustered histone 8; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; H2B VII; H2B.1; H2B.1 antibody; H2B.1A; H2B.1B; H2B.2; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/r; H2B/S; H2B/t; H2B1; H2B1.1; H2B1.2; h2B-143; H2B2; H2b-221; H2b-291b; H2b-613; H2Bb; H2BC1; H2BC10; H2BC15; H2BC17; H2BC19; H2BC21; H2BC2P; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFO; H2BFQ; h2bfr; H2BFS; H2BFT; H2BFU; H2BFWT; H2BGL105; H2B-I; H2B-II; H2B-III; H2B-IV; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2b-n; H2BQ; H2BS14; H2BS14p; H2BU1; H2B-VI; H2B-VII; H2BW1; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG17949-PA; His2B:CG33868; His2B:CG33868-PA; His2B:CG33870; His2B:CG33870-PA; His2B:CG33872; His2B:CG33872-PA; His2B:CG33874; His2B:CG33874-PA; His2B:CG33876; His2B:CG33876-PA; His2B:CG33878; His2B:CG33878-PA; His2B:CG33880; His2B:CG33880-PA; His2B:CG33882; His2B:CG33882-PA; His2B:CG33884; His2B:CG33884-PA; His2B:CG33886; His2B:CG33886-PA; His2B:CG33888; His2B:CG33888-PA; His2B:CG33890; His2B:CG33890-PA; His2B:CG33892; His2B:CG33892-PA; His2B:CG33894; His2B:CG33894-PA; His2B:CG33896; His2B:CG33896-PA; His2B:CG33898; His2B:CG33898-PA; His2B:CG33900; His2B:CG33900-PA; His2B:CG33902; His2B:CG33902-PA; His2B:CG33904; His2B:CG33904-PA; His2B:CG33906; His2B:CG33906-PA; His2B:CG33908; His2B:CG33908-PA; His2B:CG33910; His2B:CG33910-PA; HIST1H2B7; HIST1H2B7L3; hist1h2ba; HIST1H2BB; HIST1H2BB antibody; Hist1h2bc; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; Hist1h2bh; HIST1H2BI; Hist1h2bj; hist1h2bj.L; hist1h2bj.S; HIST1H2BK; HIST1H2BL

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102724334, 114483833, 128312, 158983, 24829, 255626, 286436, 291157, 3017, 3018, 319177, 319178, 319181, 319182, 319183, 319184, 319186, 319190, 361247, 440689, 68024, 680312, 691488, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A0A2R8Y619, O60814, P06899, P0C1H6, P10854, P23527, P33778, P57053, P58876, P62807, P70696, Q00729, Q16778, Q5QNW6, Q64475, Q64478, Q64524, Q6ZWY9, Q7Z2G1, Q8CGP1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880

Gene Symbols:
H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, HIST1H2BA, HIST1H2BD, HIST1H2BJ, HIST1H2BM, HIST1H2BO, LOC102724334

Immunogen:
Peptide sequence around phosphorylation site of serine 14(K-G-S(p)-K-K) derived from Human Histone H2B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540155

--


Antigen:
Phospho-Cdc25B (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDC25B

Gene Alias:
AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12531, 171103, 994

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P30305, P30306, P48966

Gene Symbols:
CDC25B

Immunogen:
Peptide sequence around phosphorylation site of serine 323 (S-P-S(p)-M-P) derived from Human CDC25B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA540161

--


Antigen:
Phospho-TrkA (Tyr701)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ntrk1

Gene Alias:
C80751; DKFZp781I14186; EC 2.7.10.1; gp140trk; high affinity nerve growth factor receptor; kinase TrkA; MTC; neurotrophic receptor tyrosine kinase 1; Neurotrophic tyrosine kinase receptor type 1; neurotrophic tyrosine kinase, receptor, type 1; Ntrk1; Oncogene TRK; p140-TrkA; Slow nerve growth factor receptor; Tkr; TRK; TRK1; TRK1-transforming tyrosine kinase protein; Trka; Trk-A; TrkA neurotrophin receptor; trkA proto-oncogene receptor; tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18211, 4914, 59109

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P04629, P35739, Q3UFB7

Gene Symbols:
Ntrk1

Immunogen:
Peptide sequence around phosphorylation site of tyrosine 701 (I-L-Y(p)-R-K) derived from Human Trk A.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG