PA549761

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PA549761-Each-of-1 In Stock ₹ 44,705.10

PA549761 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295, 12041, 29603

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O14874, O55028, Q00972

Gene Symbols

BCKDK

Immunogen

Synthesized peptide derived from Internal of human BCKD.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA553697

--

Img

Thermo Scientific

PIPA528050

--

Img

Novus Biologicals

NB519522

--

Img

Thermo Scientific

PA549892

--

Img

Thermo Scientific

PIPA575318

--

Img

Thermo Scientific

PIPA599590

--

Img

Thermo Scientific

PIPA5120441

--

Img

Thermo Scientific

PIPA536922

--

Description

  • The antibody detects endogenous levels of total BCKDK protein
  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PA549761

--


Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295, 12041, 29603

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14874, O55028, Q00972

Gene Symbols:
BCKDK

Immunogen:
Synthesized peptide derived from Internal of human BCKD.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549763

--


Antigen:
EphB6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPHB6

Gene Alias:
Cekl; chicken eph/elk receptor-like protein; EPB6; EPH receptor B6; EPHB6; EphB6v; Epherin B6; Epherin receptor B6; ephrin type A receptor; ephrin type-B receptor 6; HEP; human kinase-defective Eph-family receptor protein; MEP; MGC129910; MGC129911; Tyrosine-protein kinase-defective receptor EPH-6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13848, 2051, 312275

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08644, O15197, P0C0K7

Gene Symbols:
EPHB6

Immunogen:
Synthesized peptide derived from internal of human EPHB6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549766

--


Antigen:
Hairless

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HR

Gene Alias:
ALUNC; AU; ba; bldy; HAIR; hair growth associated; hairless; hairless homolog; Hairless protein; hr; HSA277165; HYPT4; Lysine-specific demethylase hairless; MUHH; MUHH1; N; protein hairless; rh; rh-bmh; rhino

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
55806

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43593

Gene Symbols:
HR

Immunogen:
Synthesized peptide derived from internal of human HAIR.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PA549767

--


Antigen:
HnRNP Q

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Syncrip

Gene Alias:
2610109K23Rik; 4632417O19Rik; Ab2-339; Glycine- and tyrosine-rich RNA-binding protein; GRYRBP; GRY-RBP; heterogeneous nuclear ribonucleoprotein Q; hnRNP; hnRNP Q; HNRNPQ; hnRNP-Q; HNRPQ; HNRPQ1; liver regeneration-related protein LRRG077; NS1-associated protein 1; NSAP1; Nsap1l; PP68; RRM RNA binding protein GRY-RBP; synaptotagmin binding cytoplasmic RNA interacting protein; synaptotagmin binding, cytoplasmic RNA interacting protein; synaptotagmin-binding, cytoplasmic RNA-interacting protein; Syncrip

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10492, 363113, 56403

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60506, Q7TMK9, Q7TP47

Gene Symbols:
Syncrip

Immunogen:
Synthesized peptide derived from Internal of human hnRNP Q.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG