PIPA553697

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA553697-Each-of-1 In Stock ₹ 47,015.22

PIPA553697 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295, 12041, 29603

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

0.3 mg/mL

Formulation

PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.

O14874, O55028, Q00972

Gene Symbols

BCKDK

Immunogen

Recombinant protein corresponding to Human BCKDK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LLDDHKDVVT LLAEGLRESR KHIEDEKLVR YFLDKTLTSR LGIRMLATHH LALHEDKPDF VGIICTRLSP KKIIEKWVDF ARRLCEHKYG NAPRVRINGH VAARFPFIPM PLDY Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%
  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA553697

--


Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295, 12041, 29603

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry, Western Blot

Concentration:
0.3 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O14874, O55028, Q00972

Gene Symbols:
BCKDK

Immunogen:
Recombinant protein corresponding to Human BCKDK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA553698

--


Antigen:
TUB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TUB

Gene Alias:
CELE_F10B5.4; F10B5.4; Rd5; RDOB; retinal degeneration 5; TUB; TUB bipartite transcription factor; TUB-1; tubby bipartite transcription factor; tubby candidate gene; tubby homolog; tubby homologue; tubby protein; Tubby protein homolog; Tubby protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7275

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.05 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
P50607

Gene Symbols:
TUB

Immunogen:
Recombinant protein corresponding to Human TUB

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA553699

--


Antigen:
AP5Z1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP5Z1

Gene Alias:
adapter-related protein complex 5 zeta subunit; adaptor related protein complex 5 zeta 1 subunit; adaptor related protein complex 5, zeta 1 subunit; adaptor-related protein complex 5 zeta subunit; adaptor-related protein complex 5, zeta 1 subunit; AP-5 complex subunit zeta-1; AP5Z1; KIAA0415; protein KIAA0415; SPG48; zeta; Zeta5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9907

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.5 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
O43299

Gene Symbols:
AP5Z1

Immunogen:
Recombinant protein corresponding to Human AP5Z1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA553700

--


Antigen:
DNAJC28

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNAJC28

Gene Alias:
BC020175; C21; C21orf55; C21orf78; DC42; DnaJ (Hsp40) homolog, subfamily C, member 28; DnaJ heat shock protein family (Hsp40) member C28; dnaJ homolog subfamily C member 28; DNAJC28; FLJ12894; IRA1; ORF28; TBLR2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
54943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
0.2 mg/mL

Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2

Gene Accession No.:
Q9NX36

Gene Symbols:
DNAJC28

Immunogen:
Recombinant protein corresponding to Human DNAJC28

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG