PIPA528050

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA528050-Each-of-1 In Stock ₹ 45,304.02

PIPA528050 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295, 12041, 29603

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.35 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.

O14874, O55028, Q00972

Gene Symbols

BCKDK

Immunogen

Recombinant fragment corresponding to a region within amino acids 77 and 367 of Human BCKDK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Recommended positive controls: MCF-7, MCF-7 membrane extract, Mouse brain, rat brain, rat kidney
  • Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (82%), Xenopus laevis (87%), Rhesus Monkey (98%), Bovine (98%)
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA528050

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Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial; AI327402; BCKDHKIN; BCKDK; BCKDKD; BCKD-kinase; BDK; branched chain alpha-ketoacid dehydrogenase kinase; branched chain ketoacid dehydrogenase kinase; branched-chain alpha-ketoacid dehydrogenase kinase; EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295, 12041, 29603

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
O14874, O55028, Q00972

Gene Symbols:
BCKDK

Immunogen:
Recombinant fragment corresponding to a region within amino acids 77 and 367 of Human BCKDK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA528052

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Antigen:
SERPINB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SERPINB1

Gene Alias:
1190005M04Rik; AI325983; Anti elastase; anti-elastase; EGK_14416; EI; EIA; ELANH2; epididymis luminal protein 57; epididymis secretory protein Li 27; HEL57; HEL-S-27; L M/N MN PI2; LEI; leukocyte elastase inhibitor; Leukocyte elastase inhibitor A; M/NEI; MNEI; Monocyte/neutrophil elastase inhibitor; ovalbumin; peptidase inhibitor 2; PI2; PI-2; protease inhibitor 2 (anti-elastase), monocyte/neutrophil derived; serine (or cysteine) peptidase inhibitor, clade B, member 1a; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1a; serine (or cysteine) proteinase inhibitor, clade B, member 1a; serine protease inhibitor EIA; serpin; Serpin B1; Serpin B1a; serpin family B member 1; serpin peptidase inhibitor, clade B (ovalbumin), member 1; Serpinb1; Serpinb1a

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1992

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1.01 mg/mL

Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P30740

Gene Symbols:
SERPINB1

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 294 of Human M/NEI

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA528053

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Antigen:
ETS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ETS2

Gene Alias:
AU022856; avian erythroblastosis virus E26 (v-ets) oncogene homolog 2; E26 avian leukemia oncogene 2, 3' domain; ETS proto-oncogene 2, transcription factor; Ets2; Ets-2; ETS2IT1; oncogene ETS-2; protein C-ets-2; v-ets avian erythroblastosis virus E2 oncogene homolog 2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; v-ets erythroblastosis virus E26 oncogene homolog 2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2114, 304063

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P15036

Gene Symbols:
ETS2

Immunogen:
Recombinant fragment corresponding to a region within amino acids 1 and 287 of Human ETS2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA528057

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Antigen:
NDST3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NDST3

Gene Alias:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; GlcNAc N-deacetylase/ N-sulfotransferase 3; glucosaminyl N-deacetylase/N-sulfotransferase 3; Heparan sulfate N-deacetylase 3; Heparan sulfate N-sulfotransferase 3; hNDST-3; HSST3; N-deacetylase and N-sulfotransferase 3; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3; N-deacetylase/N-sulfotransferase 3; NDST3; NDST-3; N-heparan sulfate sulfotransferase 3; N-HSST 3; UNQ2544/PRO4998

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9348

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O95803

Gene Symbols:
NDST3

Immunogen:
Recombinant fragment corresponding to a region within amino acids 30 and 398 of Human NDST3

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG