PC130100UL

MilliporeSigma™ anti-Rad51 (Ab-1), Polyclonal

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 PC130100UL-Each-of-1 In Stock ₹ 44,046.29

PC130100UL - Each of 1

₹ 44,046.29

In Stock

Quantity

1

Base Price: ₹ 44,046.29

GST (18%): ₹ 7,928.332

Total Price: ₹ 51,974.622

Antigen

Rad51

Classification

Polyclonal

Formulation

In 150mM NaCl, 100mM Tris-Glycine, pH 7.4

Immunogen

recombinant, human Rad51

Regulatory Status

RUO

Test Specificity

Recognizes the ∽43kDa Rad51 protein in ovarian tissue.

Content And Storage

−20°C

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation

Conjugate

Unconjugated

Host Species

Rabbit

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Purified

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Description

  • Specifically detects Rad51 Clone: in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Immunoprecipitation The bacterial RecA and the yeast RAD51 proteins are involved in homologous recombination and DNA repair
  • The human RAD51 protein is the homologue of these two proteins
  • While the modular structure of these proteins is conserved and the homology is very strong with the bacterial protein there are functional differences seen with RAD51 including an ATP hydrolysis rate 1/10 that seen with RecA
  • Although RAD51 is a nuclear protein and is largely absent from the cytoplasm and nucleoli, the protein lacks a nuclear localization signal and requires other proteins in a complex to be translocated into the nucleus
  • Treatment of cells with DNA synthesis inducing agents will cause an increase in the levels of RAD51 protein which then undergo a shift in distribution becoming focal in nature
  • This focal distribution may be blocked by inhibitors of transcription
  • RAD51 can be shown to interact directly with the chromosomes and during the process of meiosis, its distribution of RAD51 undergoes dynamic change
  • RAD51 has been shown to interact with a wide variety of different proteins that include the wild-type form of p53, BRCA2, and RAD52, which specifically modulates its activity.

Compare Similar Items

Show Difference

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MilliporeSigma™

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Antigen:
Rad51

Classification:
Polyclonal

Formulation:
In 150mM NaCl, 100mM Tris-Glycine, pH 7.4

Immunogen:
recombinant, human Rad51

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽43kDa Rad51 protein in ovarian tissue.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

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Antigen:
NF-κB (p65, RelA)

Classification:
Polyclonal

Formulation:
In 5mM sodium phosphate buffer, pH 7.4.

Immunogen:
a synthetic peptide corresponding to amino acids near the N-terminal domain of human NF-κB p65 (RelA), conjugated to KLH

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽65kDa NF-κB p65 (RelA) protein in Daudi cells.

Content And Storage:
−20°C

Isotype:
IgG

Applications:
ELISA, Gel Supershift, Immunoblot, Immunoblot, Immunoprecipitation

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Undiluted

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Antigen:
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Classification:
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Formulation:
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Immunogen:
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Regulatory Status:
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Test Specificity:
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Content And Storage:
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Isotype:
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Applications:
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Conjugate:
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Host Species:
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Antigen:
Serotonin 2A (5-HT2A) Receptor (22-41)

Classification:
Polyclonal

Formulation:
In 150mM NaCl, 20mM sodium phosphate, 1% BSA, pH 7.5.

Immunogen:
a synthetic peptide corresponding to amino acids 22-41 of rat 5-HT2Areceptor

Regulatory Status:
RUO

Test Specificity:
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Content And Storage:
−20°C

Isotype:
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Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat, Sheep

Form:
Liquid