PIMA133517

CD2 Monoclonal Antibody (MRC OX-34), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA133517-Each-of-1 In Stock ₹ 48,640.86

PIMA133517 - Each of 1

₹ 48,640.86

In Stock

Quantity

1

Base Price: ₹ 48,640.86

GST (18%): ₹ 8,755.355

Total Price: ₹ 57,396.215

Antigen

CD2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide; pH 7.4

Gene Accession No.

P08921

Gene Symbols

CD2

Immunogen

Activated rat T helper cells

Quantity

500 μg

Primary or Secondary

Primary

Target Species

Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

MRC OX-34

Conjugate

Unconjugated

Gene

CD2

Gene Alias

Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

497761

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIMA517483

--

Img

Thermo Scientific

PIMA517484

--

Img

Thermo Scientific

PIMA516894

--

Img

Thermo Scientific

PIMA190805

--

Img

Thermo Scientific

PIMA517387

--

Img

Thermo Scientific

PIMA516658

--

Img

Thermo Scientific

PIMA180926

--

Img

Thermo Scientific

PIMA517389

--

Description

  • MA1-33517 detects CD2 from rat samples
  • CD2 (LFA-2) is a monomeric surface antigen (MW range 45-58 kDa) of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells
  • CD2 is one of the earliest T-cell markers, being present on more than 95% of thymocytes and it is also found on some natural killer cells, but not on B lymphocytes
  • Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it
  • The interaction between CD2 and CD58 stabilizes adhesion between T cells and antigen presenting or target cells
  • Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion
  • Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58
  • Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion
  • CD2 deficiency reduces intestinal inflammation and helps to control infection
  • Diseases associated with CD2 dysfunction include penis squamous cell carcinoma and immune deficiency due to the absence of the thymus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA133517

--


Antigen:
CD2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide; pH 7.4

Gene Accession No.:
P08921

Gene Symbols:
CD2

Immunogen:
Activated rat T helper cells

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
MRC OX-34

Conjugate:
Unconjugated

Gene:
CD2

Gene Alias:
Cd2; CD2 antigen; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; CD2R; cluster of differentiation 2; Erythrocyte receptor; FLJ46032; LFA2; LFA-2; LFA-3 receptor; Ly37; Ly-37; lymphocyte antigen 37; OX34; OX-34; OX-34 antigen; OX-45 surface antigen homolog to human T lymphocyte CD2 antigen; Rosette receptor; SRBC; surface immunoglobulin superfamily molecule; T11; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
497761

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA133578

--


Antigen:
CD51/CD61

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P05106, P06756, P26008

Gene Symbols:
ITGAV, ITGB3

Immunogen:
Osteoclasts from osteoclastomas

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunomicroscopy, Immunoprecipitation, Western Blot (Agglutination)

Clone:
23C6

Conjugate:
Unconjugated

Gene:
ITGAV

Gene Alias:
1110004F14Rik; 2610028E01Rik; alpha v integrin; antigen CD61; antigen identified by monoclonal antibody L230; BDPLT16; BDPLT2; Cd51; CD61; D430040G12Rik; Dnmt3l-ps1 pseudogene; GP3A; GPIIIa; GT; INGRB3; integrin; integrin alpha V; integrin alpha-5 beta-3; integrin alpha-V; Integrin alpha-V heavy chain; Integrin alpha-V light chain; integrin alphaVbeta3; Integrin beta; integrin beta 3; integrin beta 3 (Cd61); Integrin beta3; integrin beta-3; integrin subunit alpha V; integrin subunit beta 3; integrin, alpha V; integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51); integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGAV; Itgb3; MSK8; platelet gpIIIa; platelet membrane glycoprotein IIIa; Vitronectin receptor; vitronectin receptor alpha polypeptide (VNRA); vitronectin receptor alpha subunit; vitronectin receptor subunit alpha; VNRA; VTNR

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
29302, 296456, 3685, 3690, 374209, 396420

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA133620

--


Antigen:
LAIR1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q6GTX8

Gene Symbols:
LAIR1

Immunogen:
NK cells lines B12.100 and AM.25

Quantity:
200 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
NKTA255

Conjugate:
Unconjugated

Gene:
LAIR1

Gene Alias:
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3903

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA133625

--


Antigen:
LAIR1

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q6GTX8

Gene Symbols:
LAIR1

Immunogen:
NK cells lines B12.100 and AM.25

Quantity:
500 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
NKTA255

Conjugate:
Unconjugated

Gene:
LAIR1

Gene Alias:
5133400O11Rik; BB115266; CD305; D7Bwg0421e; immunoglobulin heavy chain variable region; Lair1; Lair-1; leukocyte associated immunoglobulin like receptor 1; leukocyte-associated Ig-like receptor 1; leukocyte-associated Ig-like receptor-1; leukocyte-associated immunoglobulin-like receptor 1; rLAIR1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3903

Content And Storage:
4° C

Form:
Liquid