PIMA139416

CD20 Monoclonal Antibody (SP32), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA139416-Each-of-1 In Stock ₹ 90,864.72

PIMA139416 - Each of 1

₹ 90,864.72

In Stock

Quantity

1

Base Price: ₹ 90,864.72

GST (18%): ₹ 16,355.65

Total Price: ₹ 1,07,220.37

Antigen

CD20

Classification

Monoclonal

Concentration

Not Determined

Formulation

PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.

P11836, P19437

Gene Symbols

Ms4a1

Immunogen

Synthetic peptide from C-terminus of human CD20 protein.

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

SP32

Conjugate

Unconjugated

Gene

Ms4a1

Gene Alias

AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

12482, 931

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min
  • Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature
  • A suggested positive control is tonsil or B cell lymphoma
  • CD20 is a non-glycosylated surface phosphoprotein that has a molecular weight range of 33-37 kDa depending on the degree of phosphorylation
  • CD20 is expressed on mature and most malignant B cells, in a subpopulation of T lymphocytes and follicular dendritic cells
  • CD20 expression on B cells is synchronous with the expression of surface IgM and it regulates transmembrane calcium conductance, cell cycle progression and B-cell proliferation
  • CD20 is also associated with lipid rafts, but the intensity of this association depends on extracellular triggering, employing CD20 conformational change, and/or BCR (B cell antigen receptor) aggregation
  • After the receptor ligation, BCR and CD20 colocalize and then rapidly dissociate before BCR endocytosis, whereas CD20 remains at the cell surface
  • CD20 serves as a useful target for antibody-mediated therapeutic depletion of B cells, as it is expressed at high levels on most B-cell malignancies, but does not become internalized or shed from the plasma membrane following monoclonal antibody treatment
  • Diseases associated with CD20 dysfunction include Ms4a1-related common variable immune deficiency.

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Show Difference

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Thermo Scientific

PIMA139416

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Antigen:
CD20

Classification:
Monoclonal

Concentration:
Not Determined

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.6

Gene Accession No.:
P11836, P19437

Gene Symbols:
Ms4a1

Immunogen:
Synthetic peptide from C-terminus of human CD20 protein.

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP32

Conjugate:
Unconjugated

Gene:
Ms4a1

Gene Alias:
AA960661; APY; ATOPY; B1; B-cell differentiation antigen Ly-44; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; B-lymphocyte surface antigen B1; Bp35; Cd20; CD20 antigen; CD20 cell surface protein; CD20 receptor; CVID5; EGK_06167; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; LEU-16; Leukocyte surface antigen Leu-16; Ly44; Ly-44; Lymphocyte antigen 44; membrane spanning 4-domains A1; membrane-spanning 4-domains subfamily A member 1; membrane-spanning 4-domains, subfamily A, member 1; membrane-spanning 4-domains, subfamily A, member 2; MGC3969; MS4A1; MS4A2; S7

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
12482, 931

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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PIMA140314

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Antigen:
Calprotectin

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P05109, P06702

Gene Symbols:
S100A8, S100A9

Immunogen:
Human blood monocytes

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
27E10

Conjugate:
Biotin

Gene:
S100A8

Gene Alias:
60B8Ag; AI323541; AW546964; B8Ag; BEE11; BEE22; CAGA; CAGB; calcium binding protein; S100 protein; calgranulin A; calgranulin B; calgranulin-A; Calgranulin-B; calprotectin; calprotectin L1H subunit; Calprotectin L1L subunit; CFAG; CGLA; CGLB; chemotactic cytokine CP-10; chemotactic S100 protein; CP-10; Cystic fibrosis antigen; EGK_01322; EGK_21438; GAGB; intracellular calcium-binding protein (MRP14); L1AG; Leukocyte L1 complex heavy chain; leukocyte L1 complex light chain; LIAG; LOC100735514; LOC532569 protein; MA387; MAC387; macrophage migration inhibitory factor-related protein-14; macrophage migration inhibitory factor-related protein-8; MIF; migration inhibitory factor-related protein 14; Migration inhibitory factor-related protein 8; Mrp14; MRP-14; MRP8; MRP-8; myeloid-related protein 14; Neutrophil cytosolic 23 kDa protein; neutrophil cytosolic 7 kDa protein; NIF; p14; p23; P7; p8; Pro-inflammatory S100 cytokine; protein S100-A8; Protein S100-A9; S100 calcium binding protein A8; S100 calcium binding protein A8 (calgranulin A); S100 calcium binding protein A9; S100 calcium binding protein A9 (calgranulin B); S100 calcium binding protein A9; protein S100-A9; S100 calcium-binding protein A8; S100 calcium-binding protein A8 (calgranulin A); S100 calcium-binding protein A9; S100 calcium-binding protein A9 (calgranulin B); S100a8; S100A8/S100A9; S100a9; similar to Calgranulin A (Migration inhibitory factor-related protein 8) (MRP-8) (Cystic fibrosis antigen) (CFAG) (P8) (Leukocyte L1 complex light chain) (S100 calcium-binding protein A8) (Calprotectin L1L subunit) (Urinary stone protein band A)...; urinary stone protein band A

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
6279, 6280, 714690, 714740

Content And Storage:
4° C

Form:
Liquid

Img

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PIMA140318

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Antigen:
TLR2

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
O60603

Gene Symbols:
Tlr2

Immunogen:
Human Flag-tagged TLR2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation

Clone:
TLR2.45

Conjugate:
Unconjugated

Gene:
Tlr2

Gene Alias:
CD282; Ly105; TIL4; Tlr2; TLR-2; toll like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll-like receptor; toll-like receptor 2; toll-like receptor 2 variant 1; toll-like receptor 2 variant 2; toll-like-receptor 2, exon 1a_; Toll-like-receptor, exon 1b; Toll-like-receptor, exon 1b_; Toll-like-receptor2, exon 1a

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7097

Content And Storage:
4° C

Form:
Liquid

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PIMA140323

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Antigen:
TLR6

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
Q9Y2C9

Gene Symbols:
TLR6

Immunogen:
Human Toll-like receptor 6

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry

Clone:
TLR6.127

Conjugate:
FITC

Gene:
TLR6

Gene Alias:
CD antigen 286; CD286; TLR6; toll like receptor 6; toll-like receptor 6

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10333

Content And Storage:
4° C, store in dark

Form:
Liquid