PIMA512184

VEGF Monoclonal Antibody (VG1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA512184-Each-of-1 In Stock ₹ 45,646.26

PIMA512184 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

VEGF

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4

Gene Accession No.

P15692

Gene Symbols

VEGFA

Immunogen

Recombinant VEGF189 protein

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

VG1

Conjugate

Unconjugated

Gene

VEGFA

Gene Alias

angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

7422

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-12184 targets Vascular Endothelial Growth Factor in IF, IHC (P) and WB applications and shows reactivity with Human samples
  • VEGF (vascular endothelial growth factor) which is a 45 kDa homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis
  • VEGF has a variety of effects on vascular endothelium, including the ability to promote endothelial cell viability, mitogenesis, chemotaxis, and vascular permeability
  • The VEGF family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF
  • VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis
  • Most tumors have the absolute requirement of angiogenesis, and VEGF has been described as the most potent angiogenic cytokine linked to this process
  • To date 5 different isoforms of VEGF have been described
  • These isoforms are generated as the result of alternative splicing from a single VEGF gene
  • These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells
  • VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature
  • Studies have shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis
  • Elevated levels of VEGF is linked to POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy, Skin changes) also known as Crow-Fukase syndrome which affects multiple organs in the body.

Compare Similar Items

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Img

Thermo Scientific

PIMA512184

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Antigen:
VEGF

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P15692

Gene Symbols:
VEGFA

Immunogen:
Recombinant VEGF189 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
VG1

Conjugate:
Unconjugated

Gene:
VEGFA

Gene Alias:
angiogenic factor; etID309976.16; eVEGF120; eVEGF164; human VEGF121 homolog; MGC70609; MVCD1; ovine vascular endothelial growth factor; RP1-261G23.1; unnamed protein product; VAS; vascular endothelial growth factor; vascular endothelial growth factor (VEGF) precursor; vascular endothelial growth factor 121 isoform; vascular endothelial growth factor 164; vascular endothelial growth factor 165b; vascular endothelial growth factor 182; vascular endothelial growth factor 182 isoform; vascular endothelial growth factor 188; vascular endothelial growth factor 188 isoform; vascular endothelial growth factor 189; vascular endothelial growth factor A; vascular endothelial growth factor A121; vascular endothelial growth factor A165; vascular endothelial growth factor Aa; Vascular endothelial growth factor A-A; vascular endothelial growth factor isoform 165; vascular permeability factor; Vasculotropin; VEGF; VEGF1; VEGF164; VEGF182; VEGF188; vegfa; VEGF-A; VEGFA165b; vegfaa; VEGF-A-A; VEGFMGC70609; VPF; VPF ant; wu:fj82c06

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
7422

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512252

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Antigen:
Pds1

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P01344, P09535

Gene Symbols:
IGF2

Immunogen:
Human recombinant full length Pds1 protein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
DCS-280

Conjugate:
Unconjugated

Gene:
IGF2

Gene Alias:
AL033362; C11orf43; GRDF; Igf2; Igf-2; IGF-II; insulin like growth factor 2; insulin-like growth factor 2; insulin-like growth factor 2 (somatomedin A); insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; insulin-like growth factor type 2; M6pr; Mpr; multiplication-stimulating polypeptide; Peg2; PP1446; PP9974; preptin; somatomedin A; Somatomedin-A; T3M-11-derived growth factor

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16002, 3481

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512259

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Antigen:
CD4

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P01730

Gene Symbols:
CD4

Immunogen:
Stimulated human leukocytes

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
4B12

Conjugate:
Unconjugated

Gene:
CD4

Gene Alias:
Activation B7-1 antigen; B7; B7.1; B7-1; BB1; B-lymphocyte activation antigen B7; CD28LG; CD28LG1; CD4; CD4 antigen; CD4 antigen (p55); CD4 antigen p55; Cd4 molecule; CD4 precursor; CD4 receptor; CD4, allele 1; cd4a; CD4mut; CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); CD80 molecule; cell surface glycoprotein CD4; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; fCD4; L3T4; LAB7; Leu-3; Ly-4; lymphocyte antigen CD4; lymphocyte antigen CD4 precursor; membrane protein; p55; T-cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; T-cell surface glycoprotein CD4 precursor (T-cell surface antigen T4/Leu-3) (T-cell differentiation antigen L3T4); T-lymphocyte activation antigen CD80; W3/25; W3/25 antigen

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
920

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512272

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Antigen:
alpha Synuclein

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P37377, P37840

Gene Symbols:
SNCA

Immunogen:
Human recombinant alpha-synuclein

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
Syn 211

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
29219, 6622

Content And Storage:
4° C

Form:
Liquid