PIMA512436

EpCAM Monoclonal Antibody (323/A3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA512436-Each-of-1 In Stock ₹ 50,394.84

PIMA512436 - Each of 1

₹ 50,394.84

In Stock

Quantity

1

Base Price: ₹ 50,394.84

GST (18%): ₹ 9,071.071

Total Price: ₹ 59,465.911

Antigen

EpCAM

Classification

Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.

P16422, Q99JW5

Gene Symbols

EPCAM

Immunogen

MCF-7 human breast cancer cells

Quantity

500 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)

Clone

323/A3

Conjugate

Unconjugated

Gene

EPCAM

Gene Alias

adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Host Species

Mouse

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

17075, 4072

Content And Storage

4° C

Form

Liquid

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Description

  • MA5-12436 targets Epithelial Specific Antigen in FACS, ICC/IF, IHC (P), and RIA applications and shows reactivity with Human and Mouse samples
  • The MA5-12436 immunogen is mCF-7 human breast cancer cells
  • Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in the epithelium with a molecular weight of approximately 40 kDa, which functions as an epithelial cell adhesion molecule
  • Ep-CAM functions as a homotypic calcium-independent cell adhesion molecule, and has a direct impact on cell cycle, proliferation and metabolism of epithelial cells and fibroblasts due to its ability to rapidly induce the proto-oncogene c-myc and the cell cycle regulating genes cyclin A and E
  • Ep-CAM mediates Ca2+-independent homotypic interactions
  • Formation of Ep-CAM-mediated adhesions have a negative regulatory effect on adhesions mediated by classic cadherins, which may have strong effects on the differentiation and growth of epithelial cells
  • Ep-CAM overexpression was suggested to be associated with enhanced epithelial proliferation
  • Ep-CAM is highly expressed in human carcinomas, and is a marker for tumors of epithelial lineage
  • Ep-CAM is expressed on baso-lateral cell surface in most simple epithelia and many carcinoma types
  • Also, Ep-CAM reportedly distinguishes adenocarcinomas from pleural mesotheliomas.

Compare Similar Items

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Img

Thermo Scientific

PIMA512436

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Antigen:
EpCAM

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P16422, Q99JW5

Gene Symbols:
EPCAM

Immunogen:
MCF-7 human breast cancer cells

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Radioimmune Assays (RIA)

Clone:
323/A3

Conjugate:
Unconjugated

Gene:
EPCAM

Gene Alias:
adenocarcinoma-associated antigen; CD326; cell surface glycoprotein Trop-1; DIAR5; EGP; EGP-2; EGP314; EGP40; EPCAM; Ep-CAM; EpCAM1; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein; Epithelial glycoprotein 314; ESA; GA733-2; gp40; hEGP314; HNPCC8; human epithelial glycoprotein-2; KS 1/4 antigen; KS1/4; KSA; Ly74; lymphocyte antigen 74; M1S2; M4S1; major gastrointestinal tumor-associated protein GA733-2; mEGP314; membrane component, chromosome 4, surface marker (35kD glycoprotein); MIC18; MK-1; panepithelial glycoprotein 314; protein 289A; Protein D5.7A; Tacsd1; Tacstd1; TROP1; Trop-1 protein; Tumor-associated calcium signal transducer 1

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
17075, 4072

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512453

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Antigen:
p53

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O09185, P02340, P04637, P10361

Gene Symbols:
Tp53, Trp53

Immunogen:
SV40-transformed mouse B4 cells

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
PAb 122

Conjugate:
Unconjugated

Gene:
Tp53

Gene Alias:
Antigen NY-CO-13; bbl; BCC7; bfy; bhy; cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; p53; p53 cellular tumor antigen; p53 protein; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; phosphoprotein p53; Tp53; tp53.L; transformation related protein 53; transformation-related protein 53; Trp248; Trp53; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; tumor suppressor p53; tumor suppressor p53 phosphoprotein; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
100682525, 22059, 24842, 7157

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512484

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Antigen:
CD235a

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P02724

Gene Symbols:
GYPA

Immunogen:
Immunogen Membrane preparation from splenic hairy cell leukemia

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
JC159

Conjugate:
Unconjugated

Gene:
GYPA

Gene Alias:
AI853584; CD235; CD235a; erythroid-lineage-specific membrane sialoglycoprotein; glycophorin A; glycophorin A (MN blood group); glycophorin A (MNS blood group); glycophorin A, GPA; glycophorin Erik; glycophorin MiI; glycophorin MiV; glycophorin SAT; glycophorin Sta type C; glycophorin-A; GPA; GPErik; GPSAT; Gypa; HGNC:4702; HGpMiV; HGpMiX; HGpMiXI; HGpSta(C); HGpStaC; Mi.V glycoprotein; Mi.V glycoprotein (24 AA); MN; MN sialoglycoprotein; MNS; PAS-2; recombinant glycophorin A-B Miltenberger-DR; sialoglycoprotein alpha

Host Species:
Mouse

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
2993, 688972

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA512490

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Antigen:
CD45RA

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P08575

Gene Symbols:
PTPRC

Immunogen:
Hairy cell leukemia cells

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
4KB5

Conjugate:
Unconjugated

Gene:
PTPRC

Gene Alias:
B220; CD45; CD45 antigen; CD45 antigen isoform 1 precursor; CD45 antigen isoform 2 precursor; CD45 antigen isoform 3 precursor; CD45 antigen isoform 4 precursor; CD45 antigen isoform 5 precursor; CD45 antigen isoform 6 precursor; CD45R; GP180; LCA; L-CA; leucocyte common antigen; Leukocyte common antigen; leukocyte common antigen A; leukocyte common antigen B; LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase C; LY5; Ly-5; Lyt-4; protein tyrosine phosphatase receptor type C; protein tyrosine phosphatase, receptor type C; protein tyrosine phosphatase, receptor type, C; protein tyrosine phosphatase, receptor type, c polypeptide; Protein tyrosine phosphatase, receptor-type, c polypeptide; protein tyrosine phosphatase; alternatively spliced; PTPRC; Receptor-type tyrosine-protein phosphatase C; RT7; T100; T200; T200 glycoprotein; T200 leukocyte common antigen

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5788

Content And Storage:
4° C

Form:
Liquid