PIMA516267

Podoplanin Monoclonal Antibody (NZ-1.2), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA516267-Each-of-1 In Stock ₹ 50,993.76

PIMA516267 - Each of 1

₹ 50,993.76

In Stock

Quantity

1

Base Price: ₹ 50,993.76

GST (18%): ₹ 9,178.877

Total Price: ₹ 60,172.637

Antigen

Podoplanin

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q86YL7

Gene Symbols

PDPN

Immunogen

Synthetic peptide corresponding to amino acids 38-70 (EGGVAMPGAEDDVV) from the platelet-aggregation-stimulating (PLAG) domain of human podoplanin

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG2a λ

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

NZ-1.2

Conjugate

Unconjugated

Gene

PDPN

Gene Alias

29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10630

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Podoplanin (PDPN, T1A, gp38, Aggrus) is a mucin type-1 glycoprotein with a 40-43 kDa molecular weight
  • Podoplanin is expressed in many tumors and normal cells, especially lymphatic epithelial cells and follicular DCs
  • Podoplanin localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells
  • As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes
  • Podoplanin appears to serve as a ligand for CLEC-2 and expression is positively correlated with tumors expressing greater invasive and metastatic potential
  • Podoplanin is directly involved in cell migration, aids metastases formation and tumor cell invasion of tissue
  • Further, it has also been determined that podoplanin expression is induced through Src activation of Cas and, recently, there are indications of podoplanin presence on Th17 cells
  • Initial studies below indicate the presence of podoplanin on a small but distinct population of CD4+ cells from human PBMC
  • Dysfunction of the podoplanin protein has been linked to diseases such as lymphangioma and subglottis neoplasm
  • Podoplanin has also been proposed as a marker for lung injury due to the physiological function of the protein.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA516267

--


Antigen:
Podoplanin

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q86YL7

Gene Symbols:
PDPN

Immunogen:
Synthetic peptide corresponding to amino acids 38-70 (EGGVAMPGAEDDVV) from the platelet-aggregation-stimulating (PLAG) domain of human podoplanin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a λ

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
NZ-1.2

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10630

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516270

--


Antigen:
Podoplanin

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q62011

Gene Symbols:
PDPN

Immunogen:
Podoplanin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2a κ

Applications:
Flow Cytometry, Western Blot

Clone:
pmab-1

Conjugate:
Unconjugated

Gene:
PDPN

Gene Alias:
29kDa cytosolic podoplanin intracellular domain; Aggrus; CTA-520D8.1; E11; E11 antigen epitope; epithelial cell surface transmembrane protein antigen; glycoprotein 36; Glycoprotein 38; glycoprotein, 36-KD; GP36; Gp38; GP40; HT1A-1; hT1alpha-1; hT1alpha-2; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); Ots8; OTS-8; OTTHUMP00000009640; OTTHUMP00000044504; PA2.26; PA2.26 antigen; PDPN; PICD; Podoplanin; PSEC0003; PSEC0025; pulmonary type I alveolar epithelial cell transmembrane differentiation marker; RANDAM-2; RP23-348F1.2; RTI140; RTI40; T1a; T1A2; T1A-2; T1alpha; T1-alpha; TI1A; Transmembrane glycoprotein E11; type I cell 40 kDa protein

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
14726

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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PIMA516273

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Antigen:
TLR3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
O15455, Q99MB1

Gene Symbols:
TLR3

Immunogen:
A portion of amino acids 350-375 of mouse TLR3

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Western Blot

Clone:
27N3D4

Conjugate:
Unconjugated

Gene:
TLR3

Gene Alias:
AI957183; CD283; IIAE2; TLR 3; TLR3; TLR-3; toll like receptor 3; toll-like receptor 3; toll-like receptor 3 variant 1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
142980, 7098

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA516274

--


Antigen:
NLRP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
Q8R4B8

Gene Symbols:
NLRP3

Immunogen:
Recombinant mNLRP3 NOD domain protein (AA 216-385).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Product Type:
Antibody

Isotype:
IgG2b κ

Applications:
Western Blot

Clone:
25N10E9

Conjugate:
Unconjugated

Gene:
NLRP3

Gene Alias:
AGTAVPRL; AII; AII/AVP; Angiotensin/vasopressin receptor AII/AVP-like; AVP; C1orf7; caterpiller protein 1.1; Cias1; CLR1.1; cold autoinflammatory syndrome 1 homolog; cold autoinflammatory syndrome 1 protein; cold autoinflammatory syndrome 1 protein homolog; Cold-induced autoinflammatory syndrome 1 protein; cryopyrin; FCAS; FCAS1; FCU; FLJ95925; mast cell maturation inducible protein 1; mast cell maturation-associated-inducible protein 1; Mmig1; MWS; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; NACHT, LRR and PYD containing protein 3; NACHT, LRR and PYD domains-containing protein 3; NACHT/LRR/pyrin domain-containing protein 3; NALP3; NLR family pyrin domain containing 3; NLR family, pyrin domain containing 3; Nlrp3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; PYPAF1; PYRIN-containing APAF1-like protein 1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
216799

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid