PIMA514104
Estrogen Receptor alpha Antibody Cocktail, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514104-Each-of-1 | In Stock | ₹ 64,726.14 |
PIMA514104 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 64,726.14
GST (18%): ₹ 11,650.705
Total Price: ₹ 76,376.845
Antigen
Estrogen Receptor alpha
Classification
Cocktail
Concentration
Conc. Not Determined
Formulation
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.
P03372
Gene Symbols
ESR1
Immunogen
Recombinant human estrogen receptor protein
Regulatory Status
RUO
Gene ID (Entrez)
2099
Content And Storage
4° C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
1D5, 6F11
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species
Mouse
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA5-14104 is a mixture of two monoclonal antibodies that target Estrogen Receptor alpha
- Staining of formalin-fixed, paraffin-embedded tissues requires boiling tissues in 10mM citrate buffer (pH 6.0) for 10-20 min, followed by cooling at room temperature for 20 min
- A recommended positive control is MCF-7 cells
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Compare Similar Items
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Antigen: Estrogen Receptor alpha
Classification: Cocktail
Concentration: Conc. Not Determined
Formulation: tissue culture supernatant with 0.09% sodium azide
Gene Accession No.: P03372
Gene Symbols: ESR1
Immunogen: Recombinant human estrogen receptor protein
Regulatory Status: RUO
Gene ID (Entrez): 2099
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1D5, 6F11
Conjugate: Unconjugated
Gene: ESR1
Gene Alias: DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species: Mouse
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
Estrogen Receptor alpha
Classification:
Cocktail
Concentration:
Conc. Not Determined
Formulation:
tissue culture supernatant with 0.09% sodium azide
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
Recombinant human estrogen receptor protein
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1D5, 6F11
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species:
Mouse
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: Cdc25C
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P30307
Gene Symbols: Cdc25c
Immunogen: Recombinant human CDC25C protein
Regulatory Status: RUO
Gene ID (Entrez): 995
Content And Storage: 4° C
Form: Liquid
Applications: ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 25C14 (TC-14)
Conjugate: Unconjugated
Gene: Cdc25c
Gene Alias: CDC25; CDC25C; Cdc25m1; cell division cycle 25C; dual specificity phosphatase CDC25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
Host Species: Mouse
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
Cdc25C
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P30307
Gene Symbols:
Cdc25c
Immunogen:
Recombinant human CDC25C protein
Regulatory Status:
RUO
Gene ID (Entrez):
995
Content And Storage:
4° C
Form:
Liquid
Applications:
ChIP Assay, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
25C14 (TC-14)
Conjugate:
Unconjugated
Gene:
Cdc25c
Gene Alias:
CDC25; CDC25C; Cdc25m1; cell division cycle 25C; dual specificity phosphatase CDC25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
Host Species:
Mouse
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1 κ
Antigen: CD36
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P16671, Q08857
Gene Symbols: CD36
Immunogen: Stimulated human leukocytes
Regulatory Status: RUO
Gene ID (Entrez): 12491, 948
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone: 185-1G2
Conjugate: Unconjugated
Gene: CD36
Gene Alias: adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor
Host Species: Mouse
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2a κ
Antigen:
CD36
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P16671, Q08857
Gene Symbols:
CD36
Immunogen:
Stimulated human leukocytes
Regulatory Status:
RUO
Gene ID (Entrez):
12491, 948
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
Clone:
185-1G2
Conjugate:
Unconjugated
Gene:
CD36
Gene Alias:
adipocyte membrane protein; BDPLT10; Cd36; CD36 antigen; CD36 antigen (collagen type I receptor, thrombospondin receptor); CD36 molecule; CD36 molecule (thrombospondin receptor); CD36 protein; CHDS7; cluster determinant 36; collagen type I receptor thrombospondin receptor; collagen type I receptor, thrombospondin receptor; FAT; FAT/CD36; fatty acid translocase; fatty acid translocase/CD36; fatty acid transport protein; glycoprotein IIIb; GP3B; GP4; GPIIIB; GPIV; I79_011940; Leukocyte differentiation antigen CD36; PAS IV; PAS4; PAS-4; PAS-4 protein; PASIV; Platelet collagen receptor; Platelet glycoprotein 4; platelet glycoprotein IV; Scarb3; scavenger receptor class B, member 3; SR-B3; Thrombospondin receptor
Host Species:
Mouse
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2a κ
Antigen: p73
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: O15350
Gene Symbols: TP73
Immunogen: Purified monkey recombinant p73alpha protein (aa380-637)
Regulatory Status: RUO
Gene ID (Entrez): 7161
Content And Storage: 4° C
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: ER-15
Conjugate: Unconjugated
Gene: TP73
Gene Alias: deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; Tp73; transformation related protein 73; Trp73; Tumor protein p73
Host Species: Mouse
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1 κ
Antigen:
p73
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
O15350
Gene Symbols:
TP73
Immunogen:
Purified monkey recombinant p73alpha protein (aa380-637)
Regulatory Status:
RUO
Gene ID (Entrez):
7161
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
ER-15
Conjugate:
Unconjugated
Gene:
TP73
Gene Alias:
deltaNp73; OTTHUMP00000003479; OTTHUMP00000003480; p53-like transcription factor; p53-related protein; P73; RP23-254N4.10; TAp73; Tp73; transformation related protein 73; Trp73; Tumor protein p73
Host Species:
Mouse
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1 κ