PIMA514501
Estrogen Receptor alpha Monoclonal Antibody (SP1), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA514501-Each-of-1 | In Stock | ₹ 90,009.12 |
PIMA514501 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 90,009.12
GST (18%): ₹ 16,201.642
Total Price: ₹ 1,06,210.762
Antigen
Estrogen Receptor alpha
Classification
Monoclonal
Concentration
0.014 mg/mL
Formulation
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.
P03372
Gene Symbols
ESR1
Immunogen
Synthetic peptide derived from C-terminal of human estrogen receptor
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
SP1
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2099
Content And Storage
-20°, C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody strongly stains the nucleus of epithelial cells in breast carcinomas
- It reacts with ER alpha, 67 kDa
- No special pretreatment is required for IHC staining
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Compare Similar Items
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Antigen: Estrogen Receptor alpha
Classification: Monoclonal
Concentration: 0.014 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P03372
Gene Symbols: ESR1
Immunogen: Synthetic peptide derived from C-terminal of human estrogen receptor
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP1
Conjugate: Unconjugated
Gene: ESR1
Gene Alias: DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2099
Content And Storage: -20°, C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Estrogen Receptor alpha
Classification:
Monoclonal
Concentration:
0.014 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP1
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Progesterone Receptor
Classification: Monoclonal
Concentration: 0.08 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P06401
Gene Symbols: PGR
Immunogen: Recombinant protein encoding human progesterone receptor 412-526 aa
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP2
Conjugate: Unconjugated
Gene: PGR
Gene Alias: 9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5241
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles, store in dark
Form: Liquid
Antigen:
Progesterone Receptor
Classification:
Monoclonal
Concentration:
0.08 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P06401
Gene Symbols:
PGR
Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP2
Conjugate:
Unconjugated
Gene:
PGR
Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5241
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark
Form:
Liquid
Antigen: ErbB2 (HER-2)
Classification: Recombinant Monoclonal
Concentration: 0.122 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P04626
Gene Symbols: ERBB2
Immunogen: Recombinant protein encoding extracellular domain of human HER-2
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP3
Conjugate: Unconjugated
Gene: ERBB2
Gene Alias: avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ErbB2 (HER-2)
Classification:
Recombinant Monoclonal
Concentration:
0.122 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P04626
Gene Symbols:
ERBB2
Immunogen:
Recombinant protein encoding extracellular domain of human HER-2
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP3
Conjugate:
Unconjugated
Gene:
ERBB2
Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Cyclin D1
Classification: Recombinant Monoclonal
Concentration: 0.045 mg/mL
Formulation: PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.: P24385, P25322, P39948
Gene Symbols: CCND1
Immunogen: A synthetic peptide from C-terminus of human cyclin D1
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: SP4
Conjugate: Unconjugated
Gene: CCND1
Gene Alias: AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 12443, 58919, 595
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Cyclin D1
Classification:
Recombinant Monoclonal
Concentration:
0.045 mg/mL
Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2
Gene Accession No.:
P24385, P25322, P39948
Gene Symbols:
CCND1
Immunogen:
A synthetic peptide from C-terminus of human cyclin D1
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
SP4
Conjugate:
Unconjugated
Gene:
CCND1
Gene Alias:
AI327039; B-cell CLL/lymphoma 1; B-cell lymphoma 1 protein; BCL1; BCL-1; BCL-1 oncogene; CCND1; CCND1 protein; cD1; cDNA; CycD1; cyclin D1; Cyl-1; D11S287E; FLJ93625; G1/S-specific cyclin-D1; mRNA; PRAD1; PRAD-1; PRAD1 oncogene; U21B31
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
12443, 58919, 595
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid