PIMA514479

Cytokeratin 18 Monoclonal Antibody (E431-1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA514479-Each-of-1 In Stock ₹ 77,431.80

PIMA514479 - Each of 1

₹ 77,431.80

In Stock

Quantity

1

Base Price: ₹ 77,431.80

GST (18%): ₹ 13,937.724

Total Price: ₹ 91,369.524

Antigen

Cytokeratin 18

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

tissue culture supernatant with 0.09% sodium azide

Gene Accession No.

P05783, P05784

Gene Symbols

KRT18

Immunogen

A synthetic peptide corresponding to residues of the human CK18

Regulatory Status

RUO

Gene ID (Entrez)

16668, 3875

Content And Storage

4° C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone

E431-1

Conjugate

Unconjugated

Gene

KRT18

Gene Alias

cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04

Host Species

Rabbit

Quantity

1 mL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • MA5-14479 targets Cytokeratin 18 in IHC (P) applications and shows reactivity with Human samples
  • The MA5-14479 immunogen is a synthetic peptide corresponding to residues of the human CK18
  • Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8
  • Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18
  • Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas
  • Hepatocellular carcinomas express only cytokeratins 8 and 18
  • Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis
  • Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene
  • Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies
  • The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

Compare Similar Items

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Img

Thermo Scientific

PIMA514479

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Antigen:
Cytokeratin 18

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P05783, P05784

Gene Symbols:
KRT18

Immunogen:
A synthetic peptide corresponding to residues of the human CK18

Regulatory Status:
RUO

Gene ID (Entrez):
16668, 3875

Content And Storage:
4° C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
E431-1

Conjugate:
Unconjugated

Gene:
KRT18

Gene Alias:
cb83; Cell proliferation-inducing gene 46 protein; CK 18; CK18; CK-18; CYK18; cytokeratin 18; cytokeratin endo B; cytokeratin type -1; DAPK-1; Cytokeratin18; cytokeratin-18; dapk1; dorsal aorta proneprin kinesin-1; DreK18; Endo B; I79_023185; K 18; K18; keratin 18; keratin 18, type I; keratin 18a, tandem duplicate 1; keratin complex 1, acidic, gene 18; keratin D; Keratin, type I cytoskeletal 18; Keratin18; keratin-18; Kerd; KRT 18; Krt1-18; KRT18; krt18 {ECO:0000250; krt18a.1; LOC100008885; PIG46; sb:cb83; type I cytoskeletal 18; UniProtKB:P05783}; wu:fa13f02; wu:fb36b04

Host Species:
Rabbit

Quantity:
1 mL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514501

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Antigen:
Estrogen Receptor alpha

Classification:
Monoclonal

Concentration:
0.014 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P03372

Gene Symbols:
ESR1

Immunogen:
Synthetic peptide derived from C-terminal of human estrogen receptor

Regulatory Status:
RUO

Gene ID (Entrez):
2099

Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP1

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514505

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Antigen:
Progesterone Receptor

Classification:
Monoclonal

Concentration:
0.08 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P06401

Gene Symbols:
PGR

Immunogen:
Recombinant protein encoding human progesterone receptor 412-526 aa

Regulatory Status:
RUO

Gene ID (Entrez):
5241

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles, store in dark

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP2

Conjugate:
Unconjugated

Gene:
PGR

Gene Alias:
9930019P03Rik; BB114106; ENSMUSG00000074510; LOW QUALITY PROTEIN: progesterone receptor; NR3C3; Nuclear receptor subfamily 3 group C member 3; p4 receptor; PGR; pot. alt. progesterone receptor; putative; PR; PR-A; PR-B; Progesterone receptor; progesterone receptor A; progesterone-receptor; putative form B; steroid hormone receptor; testicular progesterone receptor; unnamed protein product

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIMA514509

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Antigen:
ErbB2 (HER-2)

Classification:
Recombinant Monoclonal

Concentration:
0.122 mg/mL

Formulation:
PBS with 1% BSA and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P04626

Gene Symbols:
ERBB2

Immunogen:
Recombinant protein encoding extracellular domain of human HER-2

Regulatory Status:
RUO

Gene ID (Entrez):
2064

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
SP3

Conjugate:
Unconjugated

Gene:
ERBB2

Gene Alias:
avian erythroblastosis oncogene B 2; Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); CD antigen CD340; CD340; c-erb B2/neu protein; c-erbB2; C-erbB-2; c-neu; epidermal growth factor receptor-related protein; erbb 2; ERBB2; erb-b2; Erbb-2; ErbB2 (pTyr1139); ErbB2 (pY1139); ErbB2 phospho Y1139; erb-b2 receptor tyrosine kinase 2; her 2; HER2; HER-2; HER-2/neu; herstatin; human epidermal growth factor receptor 2; Kiaa3023; metas; Metastatic lymph node gene 19 protein; mKIAA3023; MLN 19; MLN19; NEU; Neu oncogene; NEU proto-oncogene; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; NGL; p185erbB2; p185neu; phospho ErbB2; proto-oncogene c-ErbB-2; Proto-oncogene Neu; receptor tyrosine-protein kinase erbB-2; TKR1; Tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)

Host Species:
Rabbit

Quantity:
500 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG