PIMA515116

p38 MAPK alpha Monoclonal Antibody (J.491.1), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515116-Each-of-1 In Stock ₹ 45,304.02

PIMA515116 - Each of 1

₹ 45,304.02

In Stock

Quantity

1

Base Price: ₹ 45,304.02

GST (18%): ₹ 8,154.724

Total Price: ₹ 53,458.744

Antigen

p38 MAPK alpha

Classification

Monoclonal

Concentration

62 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.

P47811, P70618, Q16539

Gene Symbols

MAPK14

Immunogen

Recombinant p38 MAPK protein

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Porcine, Rat, Yeast

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

J.491.1

Conjugate

Unconjugated

Gene

MAPK14

Gene Alias

186F5S; anon-sts23; BG:DS00797.3; CG7393; CG7393-PA; CRK1; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; Csbp2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Dm p38b; Dmel\CG7393; Dmel_CG7393; Dmp38b; Dp38; D-p38; D-p38 MAPK; Dp38b; D-p38b; EC 2.7.11.24; ERK1; ERT2; ESTS:186F5S; etID18993.8; Exip; fk28c03; hm:zeh1243; Hog; I79_016605; LD24658p; MAP 14; MAP kinase 1; MAP kinase 11; MAP kinase 14; MAP kinase 14A; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38a; MAP kinase p38alpha; MAP kinase p38b; MAPK; MAPK 11; MAPK 14; MAPK 14A; MAPK1 antibody; Mapk11; Mapk14; mapk14a; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 14; mitogen-activated protein kinase 14a; Mitogen-activated protein kinase p38 alpha; mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; mitogen-activated protein kinase p38a; Mitogen-activated protein kinase p38b; MK14; Mpk34C; Mxi2; OTTHUMP00000216563; OTTHUMP00000216566; P38; p38 alpha; p38 alpha/Mxi2; p38 beta; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38 mitogen-activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38B; p38b MAP kinase; p38beta; p38beta2; p38b-PA; p38Hog; p38Kb; p38MAPK; PRKM11; Prkm14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; RP1-179N16.5; Sapk2; Sapk2A; SAPK2b; stress-activated p38b MAP kinase; stress-activated protein kinase 2A; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38; wu:fk28c03; zeh1243; zp38a

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100156630, 1432, 26416, 81649

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with either JNK/SAPK or p42/44 MAPK or other isoforms of p38
  • MAPK14 (p38 alpha) is a member of the stress-activated protein kinase class of MAPKs
  • The p38 MAPK cascade regulates a variety of cellular responses to stress, inflammation, and other signals
  • p38 MAPK is relatively inactive in the nonphosphorylated form and becomes rapidly activated by dual phosphorylation of a Thr-Gly-Tyr motifs
  • There are four isoforms of p38 MAPK, which differ in their tissue expression and affinity for upstream activators and downstream effectors
  • When cells are exposed to tumor necrosis factor, interleukin-1, heat shock, or other activating stimuli, activation of MAPK kinase-3 occurs by phosphorylation
  • Activated MAPK kinase-3/6 phosphorylate each residue of Thr180 and Tyr182 in p38 MAPK
  • Phospho-p38 MAPK activates ATF-2, CHOP-1, MEF-2 and other transcription factors through phosphorylation.

Compare Similar Items

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Img

Thermo Scientific

PIMA515116

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Antigen:
p38 MAPK alpha

Classification:
Monoclonal

Concentration:
62 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P47811, P70618, Q16539

Gene Symbols:
MAPK14

Immunogen:
Recombinant p38 MAPK protein

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Porcine, Rat, Yeast

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
J.491.1

Conjugate:
Unconjugated

Gene:
MAPK14

Gene Alias:
186F5S; anon-sts23; BG:DS00797.3; CG7393; CG7393-PA; CRK1; CSAID-binding protein; Csaids binding protein; CSBP; Csbp1; Csbp2; CSPB1; cytokine suppressive anti-inflammatory drug binding protein; cytokine suppressive anti-inflammatory drug binding protein 1; cytokine suppressive anti-inflammatory drug-binding protein; cytokine-supressive anti-inflammatory drug binding protein; Dm p38b; Dmel\CG7393; Dmel_CG7393; Dmp38b; Dp38; D-p38; D-p38 MAPK; Dp38b; D-p38b; EC 2.7.11.24; ERK1; ERT2; ESTS:186F5S; etID18993.8; Exip; fk28c03; hm:zeh1243; Hog; I79_016605; LD24658p; MAP 14; MAP kinase 1; MAP kinase 11; MAP kinase 14; MAP kinase 14A; MAP kinase 2; MAP kinase Mxi2; MAP kinase p38; MAP kinase p38 alpha; MAP kinase p38 beta; MAP kinase p38a; MAP kinase p38alpha; MAP kinase p38b; MAPK; MAPK 11; MAPK 14; MAPK 14A; MAPK1 antibody; Mapk11; Mapk14; mapk14a; MAX-interacting protein 2; mitogen activated protein kinase 11; mitogen activated protein kinase 14; mitogen-activated protein kinase 11; Mitogen-activated protein kinase 14; mitogen-activated protein kinase 14a; Mitogen-activated protein kinase p38 alpha; mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; mitogen-activated protein kinase p38a; Mitogen-activated protein kinase p38b; MK14; Mpk34C; Mxi2; OTTHUMP00000216563; OTTHUMP00000216566; P38; p38 alpha; p38 alpha/Mxi2; p38 beta; p38 MAP kinase; p38 MAP kinase alpha; p38 MAPK; p38 mitogen activated protein kinase; p38 mitogen-activated protein kinase; p38-2; p38a; p38ALPHA; p38-alpha; p38alpha Exip; P38B; p38b MAP kinase; p38beta; p38beta2; p38b-PA; p38Hog; p38Kb; p38MAPK; PRKM11; Prkm14; Prkm15; protein kinase, mitogen activated kinase, 11, p38beta; reactive kinase; RK; RP1-179N16.5; Sapk2; Sapk2A; SAPK2b; stress-activated p38b MAP kinase; stress-activated protein kinase 2A; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b; tRNA synthetase cofactor p38; wu:fk28c03; zeh1243; zp38a

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100156630, 1432, 26416, 81649

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515117

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Antigen:
Phospho-p70 S6 Kinase (Thr389)

Classification:
Monoclonal

Concentration:
85 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P23443, P67999, Q8BSK8

Gene Symbols:
RPS6KB1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr389 of human p70 S6 kinase

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
K.393.4

Conjugate:
Unconjugated

Gene:
RPS6KB1

Gene Alias:
10539; 2610318I15Rik; 4732464A07Rik; 70 kDa ribosomal protein S6 kinase 1; 7084; 70kDa; 7-10; AA959758; AI256796; AI314060; CG10539; CG10539-PA; CG10539-PB; Dmel\CG10539; Dmel_CG10539; Dp70[s6k]; Dp70S6k; dps6k; dS6 kinase; dS6K; d-S6K; dS6K1; EC 2.7.11.1; fs(3)07084; hypothetical protein; kinase p70S6K; KS6B1; l(3)07084; p70 p70-S6K; p70 ribosomal S6 kinase; p70 ribosomal S6 kinase alpha; p70 S6 kinase; p70 S6 kinase 1; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70 S6K; p70 S6KA; p70 S6K-alpha; p70(S6K)-alpha; p70/85s6k; p70/S6K; p70[S6 kinase]; p70[S6k]; p70[S6kinase]; p70-alpha; p70S6 kinase; p70S6k; p70-S6K; p70-S6K 1; p70S6K kinase; p70s6k protein kinase homolog; P70S6K1; p70S6K-alpha; p80-S6K 1; p85 p85S6K; Pk?6; Pk64F; protein kinase-like 64F; PS6K; p-S6K; ribosomal protein S6 kinase; ribosomal protein S6 kinase B1; ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; ribosomal protein S6 kinase polypeptide 1; ribosomal protein S6 kinase, 70kD, polypeptide 1; ribosomal protein S6 kinase, 70kDa, polypeptide 1; ribosomal protein S6 kinase, polypeptide 1; ribosomal S6 protein kinase; Rps6kb1; RPS6-p70-protein kinase; S6 K; S6 kinase; s6k; S6K kinase; S6K1; s6k11; S6K-beta-1; S6kinase; S6-kinase; S6k-PA; S6k-PB; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6198, 72508, 83840

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515118

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Antigen:
Phospho-MEK1/MEK2 (Ser221)

Classification:
Monoclonal

Concentration:
246 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
P31938, P36506, P36507, Q01986, Q02750, Q1HG70, Q63932

Gene Symbols:
MAP2K1, MAP2K2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer221 of human MEK1/2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot

Clone:
K.742.1

Conjugate:
Unconjugated

Gene:
MAP2K2

Gene Alias:
AA589381; CFC3; CFC4; dual specificity mitogen activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 2; EC 2.7.12.2; ERK activator kinase 1; ERK activator kinase 2; hypothetical protein; hypothetical protein LOC406728; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP kinase/Erk kinase 1; Map2k1; Map2k2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK1; MAPKK2; MEK 1; MEK 2; Mek1; MEK-1; Mek2; MEK-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; mitogen-activated protein kinase kinase type 2; MK2; MKK1; MKK2; MP2K1; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen activated, kinase 2, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); si:ch211-242m18.2; wu:fj56a12; wu:fj61b01; zgc:56557; zgc:56557 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170851, 26395, 26396, 478347, 5604, 5605, 58960, 611939

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515122

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Antigen:
Phospho-SMAD2 (Ser465, Ser467)

Classification:
Monoclonal

Concentration:
149 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5

Gene Accession No.:
O70436, Q15796, Q62432

Gene Symbols:
SMAD2

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer465/467 of human Smad2

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mink, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Clone:
138D4

Conjugate:
Unconjugated

Gene:
SMAD2

Gene Alias:
7120426M23Rik; EGK_09664; hMAD-2; hSMAD2; JV18; JV18-1; MAD; MAD homolog 2; Mad protein homolog; Madh2; Madr2; Mad-related protein 2; MGC22139; MGC34440; mMad2; mother against DPP homolog 2; mothers against decapentaplegic homolog 2; Mothers against decapentaplegic-like protein 2; mothers against DPP homolog 2; pSMAD2; Sma- and Mad-related protein 2; SMAD; SMAD 2; SMAD family member 2; SMAD, mothers against DPP homolog 2; Smad2; Smad-2; Smad2Deltaexon3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17126, 29357, 4087

Content And Storage:
-20°C

Form:
Liquid