PIMA515239

Chk1 Monoclonal Antibody (2G1D5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515239-Each-of-1 In Stock ₹ 49,667.58

PIMA515239 - Each of 1

₹ 49,667.58

In Stock

Quantity

1

Base Price: ₹ 49,667.58

GST (18%): ₹ 8,940.164

Total Price: ₹ 58,607.744

Antigen

Chk1

Classification

Monoclonal

Concentration

1.0 mg/mL

Formulation

PBS with 0.03% sodium azide

Gene Accession No.

O14757, O35280

Gene Symbols

Chek1

Immunogen

Purified recombinant fragment of CHK1 expressed in E. Coli.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Western Blot

Clone

2G1D5

Conjugate

Unconjugated

Gene

Chek1

Gene Alias

C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1111, 12649

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • MA5-15239 targets CHK1 in indirect ELISA, WB applications and shows reactivity with Human and mouse samples
  • The MA5-15239 immunogen is purified recombinant fragment of CHK1 expressed in E
  • Coli
  • MA5-15239 detects CHK1 which has a predicted molecular weight of approximately 56kDa
  • CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
  • CHK1 is a key mediator in the DNA damage-induced checkpoint network
  • CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
  • When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
  • Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515239

--


Antigen:
Chk1

Classification:
Monoclonal

Concentration:
1.0 mg/mL

Formulation:
PBS with 0.03% sodium azide

Gene Accession No.:
O14757, O35280

Gene Symbols:
Chek1

Immunogen:
Purified recombinant fragment of CHK1 expressed in E. Coli.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2G1D5

Conjugate:
Unconjugated

Gene:
Chek1

Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1111, 12649

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA515253

--


Antigen:
V5 Tag

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
GKPIPNPLLGLDST (V5) synthetic peptide conjugated to KLH

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
E10/V4RR

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
simian virus 5 antibody; SPV5gp2; sv5; V5; v-5; V5 Epitope Tag

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA515256

--


Antigen:
GFP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.2

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
GFP from the jellyfish Aequorea Victoria N-terminal peptide-KLH conjugated.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
GF28R

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
GFP; GFP tag; GFP2; green fluorescence; green fluorescent; Turbo eGFP

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA515256D

--


Antigen:
GFP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
MES with proprietary stabilizer and no preservative

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
GFP from the jellyfish Aequorea Victoria N-terminal peptide-KLH conjugated.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Tag

Product Type:
__

Isotype:
IgG1

Applications:
Western Blot

Clone:
GF28R

Conjugate:
DyLight 800 4X PEG

Gene:
__

Gene Alias:
GFP, GFP tag, GFP2, green fluorescence, green fluorescent, Turbo eGFP

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4°, C, do not freeze

Form:
Liquid