PIMA515067
Chk1 Monoclonal Antibody (T.59.2), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515067-Each-of-1 | In Stock | ₹ 39,785.40 |
PIMA515067 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,785.40
GST (18%): ₹ 7,161.372
Total Price: ₹ 46,946.772
Antigen
Chk1
Classification
Monoclonal
Conjugate
Unconjugated
Gene
Chek1
Gene Alias
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species
Mouse
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1111, 12649, 140583
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Clone
T.59.2
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.
O14757, O35280, Q91ZN7
Gene Symbols
Chek1
Immunogen
Purified recombinant Chk1 protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- It is not recommended to aliquot this antibody
- CHEK1 (CHK1) is a serine/threonine protein kinase involved in preventing replication when DNA integrity is compromised
- CHK1 is a key mediator in the DNA damage-induced checkpoint network
- CHK1 is an evolutionarily conserved protein kinase that functions to ensure genomic integrity upon genotoxic stress
- When the G2 or S checkpoint is abrogated by the inhibition of CHK1, p53-deficient cancer cells undergo mitotic catastrophe and eventually apoptosis, whereas normal cells are still arrested in the G1 phase
- Thus, CHK1 inhibitors can preferentially potentiate the efficacy of DNA damaging agents in cancer cells, and Chk1 is an attractive therapeutic target for cancer treatment, especially since approximately 50% of all human cancers are p53-deficient.
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Antigen: Chk1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Chek1
Gene Alias: C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1111, 12649, 140583
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Clone: T.59.2
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: O14757, O35280, Q91ZN7
Gene Symbols: Chek1
Immunogen: Purified recombinant Chk1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
Chk1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Chek1
Gene Alias:
C85740; Cell cycle checkpoint kinase; checkpoint kinase 1; checkpoint kinase 1 homolog; checkpoint kinase-1; Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1; CHK1 checkpoint homolog; Chk1-S; homolog of Chk1-S; HRD1 Protein; rad27; rad27 homolog; serine/threonine protein kinase CHK1; serine/threonine-protein kinase Chk1; Synoviolin; YBR1742; YBR274W
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1111, 12649, 140583
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Clone:
T.59.2
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
O14757, O35280, Q91ZN7
Gene Symbols:
Chek1
Immunogen:
Purified recombinant Chk1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1
Antigen: IRS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16367, 25467, 3667
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: K.346.8
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P35568, P35569, P35570
Gene Symbols: IRS1
Immunogen: Synthetic peptide corresponding to the sequence surrounding Ser307 of human IRS-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IRS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16367, 25467, 3667
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
K.346.8
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P35568, P35569, P35570
Gene Symbols:
IRS1
Immunogen:
Synthetic peptide corresponding to the sequence surrounding Ser307 of human IRS-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CEA
Classification: Monoclonal
Conjugate: Unconjugated
Gene: Ceacam5
Gene Alias: 1600029H12Rik; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; CEACAM5; Meconium antigen 100; OTTHUMP00000199033; pregnancy-specific glycoprotein 30; Psg30; sCD66e; soluble CD66e
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1048
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: H.426.3
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P06731
Gene Symbols: Ceacam5
Immunogen: Human CEA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Antigen:
CEA
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
Ceacam5
Gene Alias:
1600029H12Rik; Carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; CD66e; CEA; CEACAM5; Meconium antigen 100; OTTHUMP00000199033; pregnancy-specific glycoprotein 30; Psg30; sCD66e; soluble CD66e
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1048
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
H.426.3
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P06731
Gene Symbols:
Ceacam5
Immunogen:
Human CEA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Antigen: IRS1
Classification: Monoclonal
Conjugate: Unconjugated
Gene: IRS1
Gene Alias: G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species: Mouse
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16367, 25467, 3667
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Clone: J.566.7
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.: P35568, P35569, P35570
Gene Symbols: IRS1
Immunogen: Synthetic peptide corresponding to the sequence surrounding Ser612 of human IRS-1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Antigen:
IRS1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
IRS1
Gene Alias:
G972R; HIRS-1; Insulin receptor substrate 1; IRS1; IRS-1; IRS1IRM; pp185
Host Species:
Mouse
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16367, 25467, 3667
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Clone:
J.566.7
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and <0.02% sodium azide; pH 7.5
Gene Accession No.:
P35568, P35569, P35570
Gene Symbols:
IRS1
Immunogen:
Synthetic peptide corresponding to the sequence surrounding Ser612 of human IRS-1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1