PIMA515752

PUMA alpha Monoclonal Antibody (2A8F6), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA515752-Each-of-1 In Stock ₹ 45,646.26

PIMA515752 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

PUMA alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q80ZG6, Q96PG8, Q9BXH1

Gene Symbols

BBC3

Immunogen

Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Western Blot

Clone

2A8F6

Conjugate

Unconjugated

Gene

BBC3

Gene Alias

BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species

Mouse

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

27113, 317673

Content And Storage

-20°C

Form

Liquid

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Description

  • A suggested positive control is K562 cell lysate
  • PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
  • The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
  • PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
  • PUMA may be a direct mediator of p53-induced apoptosis
  • Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA515752

--


Antigen:
PUMA alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80ZG6, Q96PG8, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
2A8F6

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27113, 317673

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515753

--


Antigen:
PUMA alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80ZG6, Q96PG8, Q99ML1, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
2A9G5

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170770, 27113, 317673

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515754

--


Antigen:
PUMA alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80ZG6, Q96PG8, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
10C5G1

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species:
Mouse

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27113, 317673

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA515755

--


Antigen:
PUMA alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q80ZG6, Q96PG8, Q9BXH1

Gene Symbols:
BBC3

Immunogen:
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Western Blot

Clone:
10D4G7

Conjugate:
Unconjugated

Gene:
BBC3

Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
27113, 317673

Content And Storage:
-20°C

Form:
Liquid