PIMA515755
PUMA alpha Monoclonal Antibody (10D4G7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA515755-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA515755 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
PUMA alpha
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q80ZG6, Q96PG8, Q9BXH1
Gene Symbols
BBC3
Immunogen
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG1
Applications
Western Blot
Clone
10D4G7
Conjugate
Unconjugated
Gene
BBC3
Gene Alias
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species
Mouse
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
27113, 317673
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- A suggested positive control is K562 cell lysate
- PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53
- The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b
- PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53
- PUMA may be a direct mediator of p53-induced apoptosis
- Antisense inhibition of PUMA expression reduced the apoptotic response to p53, and PUMA is likely to play a role in mediating p53-induced cell death through the cytochrome c/Apaf-1-dependent pathway.
Compare Similar Items
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Antigen: PUMA alpha
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q80ZG6, Q96PG8, Q9BXH1
Gene Symbols: BBC3
Immunogen: Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 10D4G7
Conjugate: Unconjugated
Gene: BBC3
Gene Alias: BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 27113, 317673
Content And Storage: -20°C
Form: Liquid
Antigen:
PUMA alpha
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q80ZG6, Q96PG8, Q9BXH1
Gene Symbols:
BBC3
Immunogen:
Recombinant protein corresponding to amino acids 76 - 170 of human PUMA-alpha.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
10D4G7
Conjugate:
Unconjugated
Gene:
BBC3
Gene Alias:
BBC3; BCL2 binding component 3; Bcl-2 binding component 3; bcl-2-binding component 3; Bcl-2-binding component 3, isoforms 1/2; Bcl-2-binding component 3, isoforms 3/4; BH3-only; FLJ42994; JFY1; JFY-1; p53 up-regulated modulator of apoptosis; PUMA; PUMA/JFY1
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
27113, 317673
Content And Storage:
-20°C
Form:
Liquid
Antigen: ENDOG
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: Q14249
Gene Symbols: ENDOG
Immunogen: Recombinant protein corresponding to amino acids 51 - 140 of human EndoG.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Western Blot
Clone: 7F2G10
Conjugate: Unconjugated
Gene: ENDOG
Gene Alias: endo G; Endog; endonuclease G; endonuclease G, mitochondrial; mitochondrial endonuclease G
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2021, 362100
Content And Storage: -20°C
Form: Liquid
Antigen:
ENDOG
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
Q14249
Gene Symbols:
ENDOG
Immunogen:
Recombinant protein corresponding to amino acids 51 - 140 of human EndoG.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Western Blot
Clone:
7F2G10
Conjugate:
Unconjugated
Gene:
ENDOG
Gene Alias:
endo G; Endog; endonuclease G; endonuclease G, mitochondrial; mitochondrial endonuclease G
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2021, 362100
Content And Storage:
-20°C
Form:
Liquid
Antigen: MyD88
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: P22366, Q99836
Gene Symbols: MYD88
Immunogen: Recombinant protein corresponding to amino acids 176 to 280 of human MyD88.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG2b
Applications: Immunohistochemistry, Western Blot
Clone: 2E9C2
Conjugate: Unconjugated
Gene: MYD88
Gene Alias: mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17874, 4615
Content And Storage: -20°C
Form: Liquid
Antigen:
MyD88
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
P22366, Q99836
Gene Symbols:
MYD88
Immunogen:
Recombinant protein corresponding to amino acids 176 to 280 of human MyD88.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunohistochemistry, Western Blot
Clone:
2E9C2
Conjugate:
Unconjugated
Gene:
MYD88
Gene Alias:
mutant myeloid differentiation primary response 88; Myd88; MYD88D; myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; myeloid differentiation primary response protein MyD88
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17874, 4615
Content And Storage:
-20°C
Form:
Liquid
Antigen: Bim
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O43521, O54918
Gene Symbols: BCL2L11
Immunogen: Recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: 1C2C8
Conjugate: Unconjugated
Gene: BCL2L11
Gene Alias: 1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)
Host Species: Mouse
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10018, 12125
Content And Storage: -20°C
Form: Liquid
Antigen:
Bim
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O43521, O54918
Gene Symbols:
BCL2L11
Immunogen:
Recombinant protein corresponding to amino acids 2 to 198 of human Bim.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
1C2C8
Conjugate:
Unconjugated
Gene:
BCL2L11
Gene Alias:
1500006F24Rik; BAM; Bcl2 interacting mediator of cell death; bcl-2 interacting mediator of cell death; bcl-2 interacting protein Bim; BCL2 like 11; Bcl-2 like 11; Bcl-2 related apoptotic gene product BimL; bcl2-interacting mediator of cell death; BCL2L11; Bcl2-L-11; BCL2-like 11 (apoptosis facilitator); bcl-2-like protein 11; bcl-2-like protein 11-like; bcl-2-related ovarian death agonist; bcl-2-related ovarian death protein; BIM; Bim EL; Bim-A; BIM-alpha6; BIM-beta6; BIM-beta7; BIMEL; BimEL protein; BimL; BOD; OTTHUMP00000197013; OTTHUMP00000204247; Unknown (protein for MGC:134444)
Host Species:
Mouse
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10018, 12125
Content And Storage:
-20°C
Form:
Liquid