PIMA516156
CD254 (RANK Ligand) Monoclonal Antibody (12A668), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516156-Each-of-1 | In Stock | ₹ 47,956.38 |
PIMA516156 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,956.38
GST (18%): ₹ 8,632.148
Total Price: ₹ 56,588.528
Antigen
CD254 (RANK Ligand)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O14788, O35235, Q9ESE2
Gene Symbols
TNFSF11
Immunogen
A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse RANKL was used as immunogen.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
12A668
Conjugate
Unconjugated
Gene
TNFSF11
Gene Alias
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
117516, 21943, 8600
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min
- Suggested positive control: activated T cells or RAW, antigen standard for TNFSF11 (transient overexpression lysate)
- This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation
- This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response
- T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss
- This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis
- Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts
- The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy
- Two alternatively spliced transcript variants have been found.
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Antigen: CD254 (RANK Ligand)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O14788, O35235, Q9ESE2
Gene Symbols: TNFSF11
Immunogen: A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse RANKL was used as immunogen.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 12A668
Conjugate: Unconjugated
Gene: TNFSF11
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 117516, 21943, 8600
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD254 (RANK Ligand)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O14788, O35235, Q9ESE2
Gene Symbols:
TNFSF11
Immunogen:
A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse RANKL was used as immunogen.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
12A668
Conjugate:
Unconjugated
Gene:
TNFSF11
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
117516, 21943, 8600
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IKK alpha
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: O15111, Q60680
Gene Symbols: CHUK
Immunogen: His-tagged full-length human IKK alpha protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 14A231
Conjugate: Unconjugated
Gene: CHUK
Gene Alias: AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 1147, 12675, 309361
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IKK alpha
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
O15111, Q60680
Gene Symbols:
CHUK
Immunogen:
His-tagged full-length human IKK alpha protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ChIP Assay, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
14A231
Conjugate:
Unconjugated
Gene:
CHUK
Gene Alias:
AI256658; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; FLJ40509; I kappa B kinase 1; i kappa-B kinase alpha; ikappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; IkB kinase alpha subunit; IkB kinase-alpha; ikBKA; IKBKB; IKK alpha; IKK1; IKK2; Ikka; IKK-A; IKK-a kinase; IKK-alpha; IKKB; IKK-B; IKK-beta; Inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase alpha; TCF16; TCF-16; Transcription factor 16
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
1147, 12675, 309361
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: TBK1
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: Q9UHD2, Q9WUN2
Gene Symbols: TBK1
Immunogen: Synthetic peptide (YYQFKKDKAERRLAYC ) of TBK1/NAK protein.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 108A429
Conjugate: Unconjugated
Gene: TBK1
Gene Alias: 1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 29110, 299827, 481145, 533141, 56480
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
TBK1
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
Q9UHD2, Q9WUN2
Gene Symbols:
TBK1
Immunogen:
Synthetic peptide (YYQFKKDKAERRLAYC ) of TBK1/NAK protein.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
108A429
Conjugate:
Unconjugated
Gene:
TBK1
Gene Alias:
1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
29110, 299827, 481145, 533141, 56480
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-IkB alpha (Ser32, Ser36)
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P25963, Q08353, Q63746, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunoprecipitation, Western Blot
Clone: 39A1413
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 18035, 25493, 282291, 406188, 4792, 480291
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-IkB alpha (Ser32, Ser36)
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P25963, Q08353, Q63746, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Synthetic peptide containing phosphorylated serines at amino acid residues 32 and 36 of human IkBa.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Human, Mouse, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunoprecipitation, Western Blot
Clone:
39A1413
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015; ECI-6; ECI-6/IKBA; I kappa B-alpha; I(Kappa)B(alpha); I79_018146; IkappaB alpha; IkappaBalpha; I-kappaBalpha; I-kappa-B-alpha; Ikba; IKBalpha; IKB-alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha; Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha; MAD3; MAD-3; Major histocompatibility complex enhancer-binding protein MAD3; NF kappa B inhibitor alpha; NF-kappaB inhibitor alpha; NF-kappa-B inhibitor alpha; NFKB inhibitor alpha; NFKBI; Nfkbia; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha; nuclear factor of kappa light polyp gene enhancer in B-cell 1; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; Rel-associated pp40; REL-associated protein pp40; RL/IF-1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 25493, 282291, 406188, 4792, 480291
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid