PIMA524695
5-Hydroxymethylcytosine Recombinant Rabbit Monoclonal Antibody (RM236), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA524695-Each-of-1 | In Stock | ₹ 40,298.76 |
PIMA524695 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,298.76
GST (18%): ₹ 7,253.777
Total Price: ₹ 47,552.537
Antigen
5-Hydroxymethylcytosine
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone
RM236
Conjugate
Unconjugated
Gene Alias
5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2
Immunogen
BSA-conjugated 5-hydroxymethylcytosine
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- This antibody reacts to 5-hydroxymethylcytosine in both single-stranded and double-stranded DNA
- No cross reactivity with non-methylated cytosine and methylcytosine in DNA
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- 5-hydroxymethylcytosine (5-hmC) has been recently discovered in mammalian DNA
- 5-hmC results from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of oxygenases
- Initially, the 5-hmC base had been identified in Purkinje neurons, in granule cells and embryonic stem cells where it is present at high levels (up to 0,6% of total nucleotides in Purkinje cells)
- A recent report indicates that 5-hmC is also abundant in brain tissue, especially in areas that are associated with higher cognitive functions.Early evidence suggests that 5-hmC may represent an intermediate in a new pathway which demethylates DNA, converting 5-mC to cytosine
- Although its precise role has still to be shown, recent results indicate, however, that 5-hmC may play important roles distinct from 5-mC
- This may open up entirely new perspectives in epigenetic studies.
Compare Similar Items
Show Difference
Antigen: 5-Hydroxymethylcytosine
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: RM236
Conjugate: Unconjugated
Gene Alias: 5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2
Immunogen: BSA-conjugated 5-hydroxymethylcytosine
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
5-Hydroxymethylcytosine
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Dot Blot, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
RM236
Conjugate:
Unconjugated
Gene Alias:
5hmc; 5-hmc; 5-HydroxymethylCytidine; C5H7N3O2
Immunogen:
BSA-conjugated 5-hydroxymethylcytosine
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone Macro-H2A.1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ChIP Assay, ELISA, Immunocytochemistry, Luminex, Western Blot
Clone: RM248
Conjugate: Unconjugated
Gene Alias: Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1
Immunogen: Peptide corresponding to the C-terminus of human Histone macroH2A1.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone Macro-H2A.1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ChIP Assay, ELISA, Immunocytochemistry, Luminex, Western Blot
Clone:
RM248
Conjugate:
Unconjugated
Gene Alias:
Core histone macro-H2A.1; H2A histone family member Y; H2A histone family, member Y; H2A.y; H2A/y; H2AF12M; H2AFY; Histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; macroH2A1; MACROH2A1.1; macroH2A1.2; medulloblastoma antigen MU-MB-50.205; mH2A1
Immunogen:
Peptide corresponding to the C-terminus of human Histone macroH2A1.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Histone H2B
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human, Mouse, Non-human Primate
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Luminex, Western Blot
Clone: RM230
Conjugate: Unconjugated
Gene Alias: 2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B clustered histone 1; H2B clustered histone 15; H2B clustered histone 17; H2B clustered histone 19; H2B clustered histone 2, pseudogene; H2B clustered histone 21; H2B clustered histone 5; H2B clustered histone 8; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; H2B VII; H2B.1; H2B.1 antibody; H2B.1A; H2B.1B; H2B.2; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/r; H2B/S; H2B/t; H2B1; H2B1.1; H2B1.2; h2B-143; H2B2; H2b-221; H2b-291b; H2b-613; H2Bb; H2BC1; H2BC10; H2BC15; H2BC17; H2BC19; H2BC21; H2BC2P; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFO; H2BFQ; h2bfr; H2BFS; H2BFT; H2BFU; H2BFWT; H2BGL105; H2B-I; H2B-II; H2B-III; H2B-IV; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2b-n; H2BQ; H2BS14; H2BS14p; H2BU1; H2B-VI; H2B-VII; H2BW1; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG17949-PA; His2B:CG33868; His2B:CG33868-PA; His2B:CG33870; His2B:CG33870-PA; His2B:CG33872; His2B:CG33872-PA; His2B:CG33874; His2B:CG33874-PA; His2B:CG33876; His2B:CG33876-PA; His2B:CG33878; His2B:CG33878-PA; His2B:CG33880; His2B:CG33880-PA; His2B:CG33882; His2B:CG33882-PA; His2B:CG33884; His2B:CG33884-PA; His2B:CG33886; His2B:CG33886-PA; His2B:CG33888; His2B:CG33888-PA; His2B:CG33890; His2B:CG33890-PA; His2B:CG33892; His2B:CG33892-PA; His2B:CG33894; His2B:CG33894-PA; His2B:CG33896; His2B:CG33896-PA; His2B:CG33898; His2B:CG33898-PA; His2B:CG33900; His2B:CG33900-PA; His2B:CG33902; His2B:CG33902-PA; His2B:CG33904; His2B:CG33904-PA; His2B:CG33906; His2B:CG33906-PA; His2B:CG33908; His2B:CG33908-PA; His2B:CG33910; His2B:CG33910-PA; HIST1H2B7; HIST1H2B7L3; hist1h2ba; HIST1H2BB; HIST1H2BB antibody; Hist1h2bc; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; Hist1h2bh; HIST1H2BI; Hist1h2bj; hist1h2bj.L; hist1h2bj.S; HIST1H2BK; HIST1H2BL
Immunogen: Peptide corresponding to the C-terminus of human Histone H2B.
Quantity: 100 μg
Primary or Secondary: Primary
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Histone H2B
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human, Mouse, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Luminex, Western Blot
Clone:
RM230
Conjugate:
Unconjugated
Gene Alias:
2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874; Dmel_CG33876; Dmel_CG33878; Dmel_CG33880; Dmel_CG33882; Dmel_CG33884; Dmel_CG33886; Dmel_CG33888; Dmel_CG33890; Dmel_CG33892; Dmel_CG33894; Dmel_CG33896; Dmel_CG33898; Dmel_CG33900; Dmel_CG33902; Dmel_CG33904; Dmel_CG33906; Dmel_CG33908; Dmel_CG33910; fj05g08; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B clustered histone 1; H2B clustered histone 15; H2B clustered histone 17; H2B clustered histone 19; H2B clustered histone 2, pseudogene; H2B clustered histone 21; H2B clustered histone 5; H2B clustered histone 8; H2B GL105 antibody; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B I; H2B II; H2B III; H2B IV; H2B K; H2B type 12; H2B VI; H2B VII; H2B.1; H2B.1 antibody; H2B.1A; H2B.1B; H2B.2; H2B.U histone 1; H2B.W histone 1; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/o; H2B/q; H2B/r; H2B/S; H2B/t; H2B1; H2B1.1; H2B1.2; h2B-143; H2B2; H2b-221; H2b-291b; H2b-613; H2Bb; H2BC1; H2BC10; H2BC15; H2BC17; H2BC19; H2BC21; H2BC2P; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFO; H2BFQ; h2bfr; H2BFS; H2BFT; H2BFU; H2BFWT; H2BGL105; H2B-I; H2B-II; H2B-III; H2B-IV; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2b-n; H2BQ; H2BS14; H2BS14p; H2BU1; H2B-VI; H2B-VII; H2BW1; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; His2B; His2B:CG17949; His2B:CG17949-PA; His2B:CG33868; His2B:CG33868-PA; His2B:CG33870; His2B:CG33870-PA; His2B:CG33872; His2B:CG33872-PA; His2B:CG33874; His2B:CG33874-PA; His2B:CG33876; His2B:CG33876-PA; His2B:CG33878; His2B:CG33878-PA; His2B:CG33880; His2B:CG33880-PA; His2B:CG33882; His2B:CG33882-PA; His2B:CG33884; His2B:CG33884-PA; His2B:CG33886; His2B:CG33886-PA; His2B:CG33888; His2B:CG33888-PA; His2B:CG33890; His2B:CG33890-PA; His2B:CG33892; His2B:CG33892-PA; His2B:CG33894; His2B:CG33894-PA; His2B:CG33896; His2B:CG33896-PA; His2B:CG33898; His2B:CG33898-PA; His2B:CG33900; His2B:CG33900-PA; His2B:CG33902; His2B:CG33902-PA; His2B:CG33904; His2B:CG33904-PA; His2B:CG33906; His2B:CG33906-PA; His2B:CG33908; His2B:CG33908-PA; His2B:CG33910; His2B:CG33910-PA; HIST1H2B7; HIST1H2B7L3; hist1h2ba; HIST1H2BB; HIST1H2BB antibody; Hist1h2bc; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; Hist1h2bh; HIST1H2BI; Hist1h2bj; hist1h2bj.L; hist1h2bj.S; HIST1H2BK; HIST1H2BL
Immunogen:
Peptide corresponding to the C-terminus of human Histone H2B.
Quantity:
100 μg
Primary or Secondary:
Primary
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MCU
Classification: Monoclonal
Concentration: 1.00 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Western Blot
Clone: CL3576
Conjugate: Unconjugated
Gene Alias: 2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Immunogen: Recombinant Human MCU
Quantity: 100 μL
Primary or Secondary: Primary
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
MCU
Classification:
Monoclonal
Concentration:
1.00 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Western Blot
Clone:
CL3576
Conjugate:
Unconjugated
Gene Alias:
2010012O16Rik; AV064928; C10orf42; Calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; D130073L02Rik; Gm64; HsMCU; MCU; mitochondrial calcium uniporter
Immunogen:
Recombinant Human MCU
Quantity:
100 μL
Primary or Secondary:
Primary
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid