PIMA527582

Alpha A Crystallin Monoclonal Antibody (1H3.B8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527582-Each-of-1 In Stock ₹ 50,180.94

PIMA527582 - Each of 1

₹ 50,180.94

In Stock

Quantity

1

Base Price: ₹ 50,180.94

GST (18%): ₹ 9,032.569

Total Price: ₹ 59,213.509

Antigen

Alpha A Crystallin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.

P02470, P02489, P24622, P24623

Gene Symbols

CRYAA, CRYAA2

Immunogen

Native Human Alpha Crystallin

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Western Blot

Clone

1H3.B8

Conjugate

Unconjugated

Gene

CRYAA

Gene Alias

[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

102724652, 12954, 1409, 24273, 281718

Content And Storage

-20°C

Form

Liquid

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Description

  • 0.5 μg/mL was sufficient for detection of 100 ng purified alphaA crystalline by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary.∣Detects approximately 20kDa
  • Does not cross-react with alpha B-crystallin, beta L-crystallin, beta H- crystallin, gamma -crystallin, HSP25, HSP27 or HSP47 proteins
  • Lens proteins consist almost entirely of crystallins (about 95%)
  • Crystallins are also found vertebrate skeletal muscle tissue
  • In the lens, their structural function is to assist in maintaining the proper refractive index of the lens
  • The mammalian lens contains 3 major classes of crystallins: alpha, beta, and gamma
  • Alpha-crystallin is the largest of the crystallins and is composed of 2 primary gene products-alpha-A and alpha-B
  • There are at least 5 different proteins comprising the beta-crystallins
  • The gamma-crystallins are monomeric, but there are at least 5 gamma crystallins identified in bovine and rat lens
  • Alpha-Crystallin comprises 40% of total lens protein composition
  • In addition to maintaining proper refractive index, it also functions in a chaperone like manner by preventing the formation of aggregates possibly leading to cataract formation
  • It is believed that the phosphorylated states of the alpha-crystallin occur in response to cellular stress and may serve a structural control function and play a role in protein maintenance
  • Alpha-B crystallin has been linked to Alexander's disease where it accumulates in brain cells of those afflicted.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527582

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Antigen:
Alpha A Crystallin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
P02470, P02489, P24622, P24623

Gene Symbols:
CRYAA, CRYAA2

Immunogen:
Native Human Alpha Crystallin

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
1H3.B8

Conjugate:
Unconjugated

Gene:
CRYAA

Gene Alias:
[a]A-crystallin; Acry 1; Acry-1; alpha A crystallin; alpha crystallin A chain; alpha-A-crystallin; alpha-crystallin A chain; Alpha-crystallin A(1-151); Alpha-crystallin A(1-156); Alpha-crystallin A(1-157); Alpha-crystallin A(1-162); Alpha-crystallin A(1-163); Alpha-crystallin A(1-165); Alpha-crystallin A(1-168); Alpha-crystallin A(1-172); Alpha-crystallin A2 chain; Alpha-crystallin A2(1-162); Alpha-crystallin A2(1-168); Alpha-crystallin A2(1-172); CRYA 1; Crya1; Crya-1; CRYAA; CRYAA2; Crystallin Alpha 1; crystallin alpha A; crystallin, alpha 1; crystallin, alpha A; Crystallin, alpha polypeptide A; crystallin, alpha-1; CTRCT9; DAcry-1; Heat shock protein beta-4; HSPB 4; HSPB4; human alphaA-crystallin (CRYA1); lens opacity 18; LOC102724652; lop18; small heat shock protein; wu:fc06h04; zgc:92036

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
102724652, 12954, 1409, 24273, 281718

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527584

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Antigen:
DUX4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
Q9UBX2

Gene Symbols:
Dux4

Immunogen:
C-terminal 76 amino acids of human DUX4 with glutathione-s-transferase (gst) tag

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
P2B1

Conjugate:
Unconjugated

Gene:
Dux4

Gene Alias:
AW822073; double homeobox; double homeobox 4; double homeobox 4-like; double homeobox B-like 1; double homeobox protein 10; Double homeobox protein 4; double homeobox protein 4/10; Dux; DUX10; Dux4; DUX4L; Duxbl; Duxbl1; EG664783; homeobox protein; RGD1311053

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100288687

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527585

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Antigen:
NLGN4X

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
B0F2B4

Gene Symbols:
Nlgn4l

Immunogen:
Fusion protein amino acids 782-945 (intracellular C-terminus) of mouse Neuroligin 4. ∽45% identity with Neuroligin-1, -2 and -3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
S98-7

Conjugate:
Unconjugated

Gene:
Nlgn4l

Gene Alias:
ASPGX2; AUTSX2; HLNX; HNL4X; HNLX; KIAA1260; MGC22376; neuroligin 4, X-linked; neuroligin 4-like; Neuroligin X; Neuroligin-4, X-linked; NL4; NL-4; NLGN; Nlgn4; Nlgn4l; NLGN4X; UNQ365/PRO701

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100113365

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527586

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Antigen:
Metallothionein

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
PA2140

Immunogen:
Full length Pseudomonas aeruginosa Metallothionein protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bacteria

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Western Blot

Clone:
2B5

Conjugate:
Unconjugated

Gene:
PA2140

Gene Alias:
Metallothionein; Metallothionein-1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
880550

Content And Storage:
-20°C

Form:
Liquid