PIMA527633

Pan SHANK Monoclonal Antibody (N23b/49), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA527633-Each-of-1 In Stock ₹ 50,608.74

PIMA527633 - Each of 1

₹ 50,608.74

In Stock

Quantity

1

Base Price: ₹ 50,608.74

GST (18%): ₹ 9,109.573

Total Price: ₹ 59,718.313

Antigen

Pan SHANK

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

D3YZU1, Q4ACU6, Q80Z38, Q9BYB0, Q9JLU4, Q9QX74, Q9UPX8, Q9WV48, Q9Y566

Gene Symbols

Shank1, SHANK2, Shank3

Immunogen

Fusion protein amino acids 84-309 of rat Shank2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone

N23b/49

Conjugate

Unconjugated

Gene

SHANK2

Gene Alias

AI841104; AUTS17; cortactin SH3 domain-binding protein; cortactin-binding protein 1; CORTBP1; CTTNBP1; DEL22q13.3; GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; KIAA1022; Kiaa1650; mKIAA1022; proline rich synapse associated protein 1; proline rich synapse associated protein 2; proline-rich synapse associated protein 1; proline-rich synapse-associated protein 1; Proline-rich synapse-associated protein 2; ProSAP1; Prosap2; PSAP2; SAPAP-interacting protein synamon; SCZD15; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains 2; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 1; SH3 and multiple ankyrin repeat domains protein 2; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat d

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

171093, 210274, 22941, 243961, 50944, 58234, 59312, 78957, 85358

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27633 was sufficient for detection of Shank1-4 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 160kDa
  • Recognizes Shank1, 2 and 3
  • Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins
  • Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron
  • Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina
  • Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimer's disease.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA527633

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Antigen:
Pan SHANK

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
D3YZU1, Q4ACU6, Q80Z38, Q9BYB0, Q9JLU4, Q9QX74, Q9UPX8, Q9WV48, Q9Y566

Gene Symbols:
Shank1, SHANK2, Shank3

Immunogen:
Fusion protein amino acids 84-309 of rat Shank2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
N23b/49

Conjugate:
Unconjugated

Gene:
SHANK2

Gene Alias:
AI841104; AUTS17; cortactin SH3 domain-binding protein; cortactin-binding protein 1; CORTBP1; CTTNBP1; DEL22q13.3; GKAP/SAPAP interacting protein; GKAP/SAPAP-interacting protein; KIAA1022; Kiaa1650; mKIAA1022; proline rich synapse associated protein 1; proline rich synapse associated protein 2; proline-rich synapse associated protein 1; proline-rich synapse-associated protein 1; Proline-rich synapse-associated protein 2; ProSAP1; Prosap2; PSAP2; SAPAP-interacting protein synamon; SCZD15; SH3 and multiple ankyrin repeat domains 1; SH3 and multiple ankyrin repeat domains 2; SH3 and multiple ankyrin repeat domains 3; SH3 and multiple ankyrin repeat domains protein 1; SH3 and multiple ankyrin repeat domains protein 2; SH3 and multiple ankyrin repeat domains protein 3; SH3 and multiple ankyrin repeat domains protein 3 variant c-3; SH3 and multiple ankyrin repeat domains protein 3 variant c-4; SH3 and multiple ankyrin repeat domains-like protein 3 variant 1; SH3 and multiple ankyrin repeat d

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
171093, 210274, 22941, 243961, 50944, 58234, 59312, 78957, 85358

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527635

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Antigen:
Neuroligin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
Q62765, Q8N2Q7, Q99K10

Gene Symbols:
Nlgn1

Immunogen:
Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S97A-31

Conjugate:
Unconjugated

Gene:
Nlgn1

Gene Alias:
6330415N05Rik; BB179718; Kiaa1070; MGC45115; mKIAA1070; neuroligin 1; neuroligin I; Neuroligin-1; NL1; NLG 1; Nlg1; NLGN1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
116647, 192167, 22871

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527637

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Antigen:
SUR2A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
O60706, P70170, Q63563

Gene Symbols:
ABCC9

Immunogen:
Fusion protein amino acids 1505-1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Western Blot

Clone:
S319A-14

Conjugate:
Unconjugated

Gene:
ABCC9

Gene Alias:
ABC37; ABCC9; AI414027; AI449286; ATFB12; ATP binding cassette subfamily C member 9; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, subfamily C (CFTR/MRP), member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; CANTU; cardiac ventricle sulfonyl urea receptor; CMD1O; FLJ36852; membrane receptor protein; si:dkey-183c2.3; Sulfonylurea receptor 2; sulfonylurea receptor subunit 2; sulfonylurea-binding protein 2; sulphonylurea receptor 2; sulphonylurea receptor 2A; sulphonylurea receptor 2B; SUR2; SUR2A; SUR2B

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10060, 20928, 25560

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527638

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Antigen:
Versican

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.1% sodium azide; pH 7.4

Gene Accession No.:
P13611, Q62059, Q9ERB4

Gene Symbols:
VCAN

Immunogen:
Fusion protein amino acids 362-585 (glycosaminoglycan alpha domain) of mouse Versican core protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Western Blot

Clone:
S351-23

Conjugate:
Unconjugated

Gene:
VCAN

Gene Alias:
5430420N07Rik; 9430051N09; Chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan 2 (versican); chondroitin sulfate proteoglycan core protein 2; Cspg2; DPEAAE; ERVR; GHAP; glial hyaluronate-binding protein; hdf; heart defect; large fibroblast proteoglycan; NG2; PGM; PG-M; PG-M core protein; PG-M(V0); PG-M(V1); V1 Neo; VCAN; versican; versican core protein; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M); versican proteoglycan; Versican V0; WGN; WGN 1; WGN1

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114122, 13003, 1462

Content And Storage:
-20°C

Form:
Liquid