PIMA527687
GRP78 Monoclonal Antibody (6H4-2G7), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA527687-Each-of-1 | In Stock | ₹ 53,047.20 |
PIMA527687 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,047.20
GST (18%): ₹ 9,548.496
Total Price: ₹ 62,595.696
Antigen
GRP78
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.
P06761, P11021, P16474, P20029, Q0VCX2, Q91883
Gene Symbols
Hspa5, KAR2
Immunogen
Full-length his-tagged human GRP78
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Bovine, Fungi, Hamster, Human, Mouse, Rhesus Monkey, X. laevis, Yeast
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Western Blot
Clone
6H4-2G7
Conjugate
Unconjugated
Gene
Hspa5
Gene Alias
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100008764, 100689305, 14828, 25617, 3309, 397850, 415113, 703193, 853418
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- 0.5 μg/mL of MA5-27687 was sufficient for detection of Grp78 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.∣Detects approximately 78kDa
- GRP78 is a 78 kDa glucose regulated protein that belongs to the family of heat shock proteins that include HSP70
- GRP78 is a resident protein of the endoplasmic reticulum (ER) and associates transiently with a variety of newly synthesized secretory and membrane proteins
- GRP78 may also interact with mutant and misfolded proteins, marking them for degradation
- The highly conserved sequence Lys-Asp-Glu-Leu (KDEL) is present at the C-terminus of GRP78 and other resident ER proteins including glucose regulated protein 94 (GRP94) and protein disulfide isomerase (PDI)
- The KDEL signal is recognized by the KDEL receptor and this interaction ensures recycling of escaped ER proteins back to the ER
- GRP78’s involvement in correct folding of proteins and degradation of misfolded proteins is via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate
- GRP78 is critical for maintenance of cell homeostasis and the prevention of apoptosis
- GRP78 protein levels have been shown to be a reliable biomarker of hypoglycemia and serves a neuroprotective function in neurons exposed to glutamate and oxidative stress
- GRP78 levels are reduced in the brains of Alzheimer's Disease patients, and decreased expression of GRP78 is found associated with missense mutations in the human presenilin-1 (PS1) gene
- Further, the induction of the GRP78 protein has been associated with the development of drug-resistance to antitumor drugs.
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Antigen: GRP78
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P06761, P11021, P16474, P20029, Q0VCX2, Q91883
Gene Symbols: Hspa5, KAR2
Immunogen: Full-length his-tagged human GRP78
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Fungi, Hamster, Human, Mouse, Rhesus Monkey, X. laevis, Yeast
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 6H4-2G7
Conjugate: Unconjugated
Gene: Hspa5
Gene Alias: 78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100008764, 100689305, 14828, 25617, 3309, 397850, 415113, 703193, 853418
Content And Storage: -20°C
Form: Liquid
Antigen:
GRP78
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P06761, P11021, P16474, P20029, Q0VCX2, Q91883
Gene Symbols:
Hspa5, KAR2
Immunogen:
Full-length his-tagged human GRP78
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Fungi, Hamster, Human, Mouse, Rhesus Monkey, X. laevis, Yeast
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
6H4-2G7
Conjugate:
Unconjugated
Gene:
Hspa5
Gene Alias:
78 kDa glucose-regulated protein; 78 kDa glucose-regulated protein homolog; 78-kD glucose-regulated protein precursor; AL022860; AU019543; baffled; Binding-immunoglobulin protein; bip; BiP protein; BiP/Grp78; cb865; D2Wsu141e; D2Wsu17e; Endoplasmic reticulum chaperone BiP; endoplasmic reticulum chaperone BiP; 78 kDa glucose-regulated protein; endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; epididymis secretory sperm binding protein Li 89n; fb60h09; fi36d04; FLJ26106; glucose regulated protein, 78 kDa; glucose-regulated protein; glucose-regulated protein, 78kDa; GRP 78; grp78; GRP-78; heat shock 70 kDa protein 5; heat shock 70 kDa protein 5a; heat shock 70kD protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); heat shock 70kDa protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A (Hsp70) member 5; heat shock protein family A (Hsp70) member 5 L homeolog; heat shock protein family A member 5; heavy-chain binding protein BiP; HEL-S-89n; Hsce70; hsp70; Hsp70 family ATPase KAR2; HSP70 family protein 5; HSPA 5; HSPA5; hspa5.L; hspa5a; I79_019946; immunoglobulin binding protein; immunoglobulin heavy chain-binding protein; Immunoglobulin heavy chain-binding protein homolog; J1248; KAR2; mBiP; MIF2; Sez7; SEZ-7; SSD1; Steroidogenesis-activator polypeptide; wu:fb60h09; wu:fi36d04; XAP-1; XAP-1 antigen; XELAEV_180384511mg; YJL034W; zgc:55994; zgc:77606
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100008764, 100689305, 14828, 25617, 3309, 397850, 415113, 703193, 853418
Content And Storage:
-20°C
Form:
Liquid
Antigen: HSF1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P38532, Q00613, Q08DJ8
Gene Symbols: Hsf1
Immunogen: Purified recombinant mouse HSF1 protein, with epitope mapping to amino acids 378-395
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Gel Shift, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation
Clone: 10H8
Conjugate: Unconjugated
Gene: Hsf1
Gene Alias: AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
Content And Storage: -20°C
Form: Liquid
Antigen:
HSF1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P38532, Q00613, Q08DJ8
Gene Symbols:
Hsf1
Immunogen:
Purified recombinant mouse HSF1 protein, with epitope mapping to amino acids 378-395
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Guinea Pig, Hamster, Human, Mouse, Rabbit, Rat, Rhesus Monkey
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Gel Shift, Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation
Clone:
10H8
Conjugate:
Unconjugated
Gene:
Hsf1
Gene Alias:
AA960185; heat shock factor 1; heat shock factor 2; Heat shock factor protein 1; Heat shock transcription factor 1; heat shock transcription factor 1 alpha isoform; heat shock transcription factor 1 beta isoform; heat shock transcription factor 1 gammaalpha isoform; heat shock transcription factor 1 gammabeta isoform; HSF; HSF 1; Hsf1; Hsf1alpha; Hsf1beta; Hsf1gammaalpha; Hsf1gammabeta; HSTF 1; HSTF1
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100350887, 100762942, 101787582, 15499, 3297, 506235, 714078, 79245
Content And Storage:
-20°C
Form:
Liquid
Antigen: ERp57
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P30101
Gene Symbols: PDIA3
Immunogen: Human recombinant ERp57 (Grp58) protein corresponding to amino acids 25 - 505 (his-tagged)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Western Blot
Clone: 4F9
Conjugate: Unconjugated
Gene: PDIA3
Gene Alias: 58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-iso
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 2923
Content And Storage: -20°C
Form: Liquid
Antigen:
ERp57
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P30101
Gene Symbols:
PDIA3
Immunogen:
Human recombinant ERp57 (Grp58) protein corresponding to amino acids 25 - 505 (his-tagged)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Western Blot
Clone:
4F9
Conjugate:
Unconjugated
Gene:
PDIA3
Gene Alias:
58 kDa glucose-regulated protein; 58 kDa microsomal protein; 58kDa; Disulfide isomerase ER-60; endoplasmic reticulum P58; endoplasmic reticulum protein; endoplasmic reticulum resident protein 57; Endoplasmic reticulum resident protein 60; epididymis secretory protein Li 269; epididymis secretory sperm binding protein Li 93n; ER p57; ER protein 57; ER protein 60; ER60; ER-60 protease; Erp; ERp 57; ERp57; ERP57 protein; ERP60; ERp61; glucose regulated protein 58; glucose regulated protein 58kD; glucose regulated protein, 58 kDa; glucose regulated protein, 58kDa; GRP 57; GRP 58; GRP57; Grp58; grp-58; HEL-S-269; HEL-S-93n; HIP-70; HsT17083; I79_003765; oxidoreductase ERp57; p58; PDI; PDIA 3; PDIA3; PDI-Q2; phospholipase C, alpha; phospholipase C-alpha; PI PLC; PI-PLC; PLC alpha; PLC[a]; Plca; protein disulfide isomerase associated 3; protein disulfide isomerase family A member 3; protein disulfide isomerase family A, member 3; protein disulfide isomerase-associated 3; protein disulfide-iso
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
2923
Content And Storage:
-20°C
Form:
Liquid
Antigen: mGluR5
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: P31424, P41594, Q3UVX5
Gene Symbols: Grm5
Immunogen: Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone: S75-33
Conjugate: Unconjugated
Gene: Grm5
Gene Alias: 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 108071, 24418, 2915
Content And Storage: -20°C
Form: Liquid
Antigen:
mGluR5
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P31424, P41594, Q3UVX5
Gene Symbols:
Grm5
Immunogen:
Fusion protein amino acids 824-1203 (cytoplasmic C-terminus) of rat mGluR5b
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
Clone:
S75-33
Conjugate:
Unconjugated
Gene:
Grm5
Gene Alias:
6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
108071, 24418, 2915
Content And Storage:
-20°C
Form:
Liquid