PIMA528055

Phospho-Src (Tyr416) Recombinant Rabbit Monoclonal Antibody (SrcY416-C4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA528055-Each-of-1 In Stock ₹ 47,956.38

PIMA528055 - Each of 1

₹ 47,956.38

In Stock

Quantity

1

Base Price: ₹ 47,956.38

GST (18%): ₹ 8,632.148

Total Price: ₹ 56,588.528

Antigen

Phospho-Src (Tyr416)

Classification

Recombinant Monoclonal

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P05480, P12931

Gene Symbols

SRC

Immunogen

A synthetic phospho-peptide corresponding to residues surrounding Tyr416 of human phospho Src.

Quantity

200μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG κ

Applications

Flow Cytometry

Clone

SrcY416-C4

Conjugate

Unconjugated

Gene

SRC

Gene Alias

ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc

Host Species

Rabbit

Purification Method

Protein A/G

Regulatory Status

RUO

Gene ID (Entrez)

20779, 6714

Content And Storage

-20°C

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • SRC is a cytoplasmic tyrosine kinase and proto-oncogene involved in the regulation of embryonic development and cell growth
  • SRC is involved in the regulation of growth and differentiation of eukaryotic cells
  • SRC associates with the cytoplasmic region of various cell surface receptors to facilitate signal transduction, and is also involved in cytoskeletal organization, cell cycle regulation, and apoptosis
  • In humans, the gene encoding SRC is present on chromosome 20
  • Activity of SRC is regulated by two tyrosine residues (Tyr 416 and Tyr527), and phosphorylation of these two sites have opposing effects
  • Phosphorylation of Tyr416 in the activation loop of the kinase domain upregulates enzyme activity while the phosphorylation of Tyr527 decreases enzyme activity
  • Mutations in the SRC gene could be involved in the malignant progression of colon cancer
  • Two transcript variants encoding the same SRC protein have been found thus far.

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Show Difference

Img

Thermo Scientific

PIMA528055

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Antigen:
Phospho-Src (Tyr416)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P05480, P12931

Gene Symbols:
SRC

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr416 of human phospho Src.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
SrcY416-C4

Conjugate:
Unconjugated

Gene:
SRC

Gene Alias:
ASV; AW259666; csrc; c-SRC; c-src protein, C terminus; EC 2.7.10.2; fc54g04; Neuronal proto-oncogene tyrosine-protein kinase Src; non-tyrosine protein kinase; ORF; OTTHUMP00000174476; OTTHUMP00000174477; OTTHUMP00000174478; p60-Src; p60-Src-1; PP60C-SCR; pp60c-src; pp60src; pp60v-src; protein-tyrosine kinase; proto-oncogene c-Src; protooncogene SRC, Rous sarcoma; Proto-oncogene tyrosine-protein kinase Src; Rous sarcoma oncogene; RP5-823N20.1; sb:cb864; SDR; src; src downstream region; src oncogene; SRC proto-oncogene, non-receptor tyrosine kinase; SRC proto-oncogene, non-receptor tyrosine kinase L homeolog; SRC proto-oncogene, non-receptor tyrosine kinase S homeolog; src.L; src.S; SRC1; src-1; src1-A; src-a; src-b; THC6; transforming protein; tyrosine kinase pp60c-src; tyrosine protein kinase c-src; tyrosine protein kinase pp60-c-src; tyrosine-protein kinase SRC-1; Unknown; v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog; v-src sarcoma viral oncogene; wu:fc54g04; XELAEV_18046582mg; xsrc

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
20779, 6714

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA528057

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Antigen:
Phospho-Stat1 (Ser727)

Classification:
Recombinant Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P42224

Gene Symbols:
STAT1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser727 of human phospho Stat1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Stat1S727-C6

Conjugate:
FITC

Gene:
STAT1

Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
6772

Content And Storage:
4° C, store in dark

Form:
Liquid

Img

Thermo Scientific

PIMA528058

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Antigen:
Phospho-Stat1 (Ser727)

Classification:
Recombinant Monoclonal

Concentration:
__

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P42224

Gene Symbols:
STAT1

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser727 of human phospho Stat1.

Quantity:
100 Tests

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Stat1S727-C6

Conjugate:
PE

Gene:
STAT1

Gene Alias:
2010005J02Rik; AA408197; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription-1; STAT; STAT 1; STAT1; STAT-1; stat1 alpha; STAT91; transcription factor ISGF-3; transcription factor ISGF-3 components p91/p84

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
6772

Content And Storage:
4° C

Form:
Liquid

Img

Thermo Scientific

PIMA528069

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Antigen:
Phospho-ZAP70/Syk (Tyr319, Tyr352)

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P43403, P43404

Gene Symbols:
ZAP70

Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr319/Tyr352 of human phospho Zap70/Syk.

Quantity:
200μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG κ

Applications:
Flow Cytometry

Clone:
Zap70Y319-A3

Conjugate:
Unconjugated

Gene:
ZAP70

Gene Alias:
70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD

Host Species:
Rabbit

Purification Method:
Protein A/G

Regulatory Status:
RUO

Gene ID (Entrez):
22637, 7535

Content And Storage:
-20°C

Form:
Liquid