PIMA528270
CD117 (c-Kit) Monoclonal Antibody (2B8/BM), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528270-Each-of-1 | In Stock | ₹ 44,876.22 |
PIMA528270 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,876.22
GST (18%): ₹ 8,077.72
Total Price: ₹ 52,953.94
Antigen
CD117 (c-Kit)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
Q2HWD6
Gene Symbols
KIT
Immunogen
Porcine bone marrow cells (BMC)
Quantity
100μg
Primary or Secondary
Primary
Target Species
Porcine
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone
2B8/BM
Conjugate
Unconjugated
Gene
KIT
Gene Alias
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
396810
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- This antibody recognizes CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, for the isolation and enrichment of porcine stem cells
- KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor)
- KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit
- KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells
- Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism
- Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth
- c-Kit is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
- Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
- This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
- SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
- c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.
Compare Similar Items
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Antigen: CD117 (c-Kit)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: Q2HWD6
Gene Symbols: KIT
Immunogen: Porcine bone marrow cells (BMC)
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Porcine
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: 2B8/BM
Conjugate: Unconjugated
Gene: KIT
Gene Alias: belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 396810
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD117 (c-Kit)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
Q2HWD6
Gene Symbols:
KIT
Immunogen:
Porcine bone marrow cells (BMC)
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Porcine
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
2B8/BM
Conjugate:
Unconjugated
Gene:
KIT
Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
396810
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD11a (LFA-1alpha)
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: ITGAL
Immunogen: Porcine alveolar macrophages
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Porcine
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry
Clone: BL1H8
Conjugate: FITC
Gene: ITGAL
Gene Alias: (p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 733681
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
CD11a (LFA-1alpha)
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.:
0
Gene Symbols:
ITGAL
Immunogen:
Porcine alveolar macrophages
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Porcine
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
BL1H8
Conjugate:
FITC
Gene:
ITGAL
Gene Alias:
(p180); alpha L integrin; antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; antigen CD11A p180; CD11 antigen-like family member A; CD11a; integrin alpha L; integrin alphaL; integrin alpha-L; integrin alpha-L precursor; integrin gene promoter; integrin subunit alpha L; integrin surface receptor; integrin, alpha L; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); ITGAL; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; Ly-15; Ly-21; lymphocyte antigen 15; lymphocyte function associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; lymphocyte function-associated antigen-1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
733681
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid
Antigen: CD11a/CD18
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: ITGAL, ITGB2
Immunogen: Equine leucocytes
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Equine
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry
Clone: CVS9
Conjugate: PE
Gene: ITGAL
Gene Alias: antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11a; CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; Complement receptor C3 subunit beta; integrin alpha L; integrin alpha-L; integrin beta chain, beta 2; integrin beta-2; integrin gene promoter; integrin subunit alpha L; integrin subunit beta 2; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGAL; ITGB2; LAD; LCAMB; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte cell adhesion molecule CD18; leukocyte function-associated molecule 1 alpha chain; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; MAC-1; MF17; MFI7
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100056128, 100065508
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Lyophilized
Antigen:
CD11a/CD18
Classification:
Monoclonal
Concentration:
Conc. Not Determined
Formulation:
PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
Gene Accession No.:
0
Gene Symbols:
ITGAL, ITGB2
Immunogen:
Equine leucocytes
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Equine
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry
Clone:
CVS9
Conjugate:
PE
Gene:
ITGAL
Gene Alias:
antigen CD11A (p180); antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; CD11 antigen-like family member A; CD11a; CD18; cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor); Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement component 3 receptor 3 and 4 subunit; complement receptor C3 beta-subunit; Complement receptor C3 subunit beta; integrin alpha L; integrin alpha-L; integrin beta chain, beta 2; integrin beta-2; integrin gene promoter; integrin subunit alpha L; integrin subunit beta 2; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); ITGAL; ITGB2; LAD; LCAMB; Leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte cell adhesion molecule CD18; leukocyte function-associated molecule 1 alpha chain; leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C; LFA-1; LFA-1 alpha; LFA1A; LFA-1A; lymphocyte function-associated antigen 1; lymphocyte function-associated antigen 1, alpha polypeptide; MAC-1; MF17; MFI7
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100056128, 100065508
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Lyophilized
Antigen: CD11b
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.: 0
Gene Symbols: ITGAM
Immunogen: __
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Bovine
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry
Clone: CC126
Conjugate: FITC
Gene: ITGAM
Gene Alias: antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 407124
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form: Liquid
Antigen:
CD11b
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA and 0.09% sodium azide
Gene Accession No.:
0
Gene Symbols:
ITGAM
Immunogen:
__
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Bovine
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry
Clone:
CC126
Conjugate:
FITC
Gene:
ITGAM
Gene Alias:
antigen CD11b (p170); antigen CD11b (p170); macrophage antigen alpha polypeptide; CD11 antigen-like family member B; CD11b; CD11B (p170); CD11b/CD18; cell surface glycoprotein MAC-1 alpha subunit; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; complement component receptor 3 alpha-a; complement receptor type 3; CR3; CR-3 alpha chain; CR3A; F730045J24Rik; integrin alpha M; integrin alpha-M; integrin subunit alpha M; integrin, alpha M; integrin, alpha M (complement component 3 receptor 3 subunit); ITGAM; Leukocyte adhesion receptor MO1; leukocyte integrin alpha-M chain; LOC100351865; Ly-40; MAC1; Mac-1; Mac-1 alpha; Mac-1 alpha (Mac1A); MAC-1 alpha subunit; MAC1A; Mac-1a; macrophage antigen alpha; macrophage antigen alpha polypeptide; MGC117044; MO1A; Neutrophil adherence receptor; neutrophil adherence receptor alpha-M subunit; SLEB6; unnamed protein product
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
407124
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
Form:
Liquid