PIMA528806
CD117 (c-Kit) Monoclonal Antibody (kit2c75), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA528806-Each-of-1 | In Stock | ₹ 36,534.12 |
PIMA528806 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 36,534.12
GST (18%): ₹ 6,576.142
Total Price: ₹ 43,110.262
Antigen
CD117 (c-Kit)
Classification
Monoclonal
Concentration
0.5 mg/mL
Formulation
BBS with no preservative; pH 8.2
Gene Accession No.
Q08156
Gene Symbols
KIT
Immunogen
Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
Quantity
1 mL
Primary or Secondary
Primary
Target Species
Chicken
Product Type
Antibody
Isotype
IgG2a κ
Applications
Flow Cytometry
Clone
kit2c75
Conjugate
Unconjugated
Gene
KIT
Gene Alias
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species
Mouse
Purification Method
purified
Regulatory Status
RUO
Gene ID (Entrez)
378783
Content And Storage
4° C
Form
Liquid
Related Products
Description
- KIT (c-KIT) is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor)
- KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit
- KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells
- Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism
- Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth
- c-Kit is expressed in hematopoietic stem cells, germ cells, mast cells and gastrointestinal tract cajal cells
- Upon binding of its ligand stem cell factor (SCF), c-kit dimerizes, resulting in receptor activation and autophosphorylation of various tyrosine residues including tyrosine 703 located on the cytoplasmic domain of the receptor
- This modification allows docking of Grb2 and activation of the Ras/ERK signaling pathway
- SCF/c-kit can activate multiple downstream signaling pathways including PI3K, PLC-gamma and JAK/STAT
- c-kit receptor activation is essential for hematopoiesis, stem cell maintenance and gametogenesis.
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Antigen: CD117 (c-Kit)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: BBS with no preservative; pH 8.2
Gene Accession No.: Q08156
Gene Symbols: KIT
Immunogen: Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Chicken
Product Type: Antibody
Isotype: IgG2a κ
Applications: Flow Cytometry
Clone: kit2c75
Conjugate: Unconjugated
Gene: KIT
Gene Alias: belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 378783
Content And Storage: 4° C
Form: Liquid
Antigen:
CD117 (c-Kit)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
BBS with no preservative; pH 8.2
Gene Accession No.:
Q08156
Gene Symbols:
KIT
Immunogen:
Sp/chkit4A4 cells (Sp2/0 cells transfected with chicken c-Kit cDNA)
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Chicken
Product Type:
Antibody
Isotype:
IgG2a κ
Applications:
Flow Cytometry
Clone:
kit2c75
Conjugate:
Unconjugated
Gene:
KIT
Gene Alias:
belly-spot; Bs; CD117; ckit; C-Kit; c-KIT gene1; c-kit protein; c-kit proto-oncogene protein; c-kit receptor; c-kit receptor tyrosine kinase; dominant spotting; Dominant white spotting; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; kit oncogene; KIT proto-oncogene receptor tyrosine kinase; KIT proto-oncogene, receptor tyrosine kinase; mast cell growth factor receptor; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; MGF; p145 c-kit; PBT; Piebald trait protein; protein kinase; proto-oncogene c-Kit; proto-oncogene tyrosine-protein kinase Kit; receptor tyrosine kinase c-kit; receptor tyrosine kinase type III; SCFR; SCO1; SCO5; Sl; soluble KIT variant 1; SOW3; spotted sterile male; Ssm; Steel Factor Receptor; Tr-kit; tyrosine kinase receptor; tyrosine kinase receptor c-KIT; tyrosine-protein kinase Kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein; W
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
378783
Content And Storage:
4° C
Form:
Liquid
Antigen: MHC Class II (I-A/I-E)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with sucrose and <0.1% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Splenic leukocytes from an outbred nine-week-old chicken
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Avian, Chicken
Product Type: Antibody
Isotype: IgM κ
Applications: Flow Cytometry
Clone: CIa
Conjugate: Biotin
Gene: __
Gene Alias: Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II IE-b, MHC class II protein, MHC H2-IE-beta cell surface glycoprotein, response to metastatic cancers 1, Rmcs1
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Form: Liquid
Antigen:
MHC Class II (I-A/I-E)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with sucrose and <0.1% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Splenic leukocytes from an outbred nine-week-old chicken
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Avian, Chicken
Product Type:
Antibody
Isotype:
IgM κ
Applications:
Flow Cytometry
Clone:
CIa
Conjugate:
Biotin
Gene:
__
Gene Alias:
Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II IE-b, MHC class II protein, MHC H2-IE-beta cell surface glycoprotein, response to metastatic cancers 1, Rmcs1
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Form:
Liquid
Antigen: MHC Class II (I-A/I-E)
Classification: Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with sucrose and <0.1% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Splenic leukocytes from an outbred nine-week-old chicken
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Avian, Chicken
Product Type: Antibody
Isotype: IgM κ
Applications: Flow Cytometry
Clone: CIa
Conjugate: FITC
Gene: __
Gene Alias: Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II I
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
MHC Class II (I-A/I-E)
Classification:
Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with sucrose and <0.1% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Splenic leukocytes from an outbred nine-week-old chicken
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Avian, Chicken
Product Type:
Antibody
Isotype:
IgM κ
Applications:
Flow Cytometry
Clone:
CIa
Conjugate:
FITC
Gene:
__
Gene Alias:
Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II I
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: MHC Class II (I-A/I-E)
Classification: Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with sucrose and <0.1% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Splenic leukocytes from an outbred nine-week-old chicken
Quantity: 1 mL
Primary or Secondary: Primary
Target Species: Avian, Chicken
Product Type: Antibody
Isotype: IgM κ
Applications: Flow Cytometry
Clone: CIa
Conjugate: PE
Gene: __
Gene Alias: Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II I
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Form: Liquid
Antigen:
MHC Class II (I-A/I-E)
Classification:
Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with sucrose and <0.1% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Splenic leukocytes from an outbred nine-week-old chicken
Quantity:
1 mL
Primary or Secondary:
Primary
Target Species:
Avian, Chicken
Product Type:
Antibody
Isotype:
IgM κ
Applications:
Flow Cytometry
Clone:
CIa
Conjugate:
PE
Gene:
__
Gene Alias:
Abeta, AI323765, AI845868, cell surface glycoprotein, E-alpha-f, H-2 class II histocompatibility antigen, A beta chain, H-2 class II histocompatibility antigen, E-D alpha chain, H-2 class II histocompatibility antigen, E-K alpha chain, H-2 class II histocompatibility antigen, E-U alpha chain, H-2 class II histocompatibility antigen, I-E beta chain, H-2Ab, H2-Ab, H2-Ab1, H-2Ea, H2-Ea, H2-Ea-ps, H2Eb, H-2Eb, H2-Eb1, H2-iabeta, H2-IE-alpha, histocompatibility 2, class II antigen A, beta 1, histocompatibility 2, class II antigen E alpha, histocompatibility 2, class II antigen E alpha, pseudogene, histocompatibility 2, class II antigen E beta, Ia2, Ia-2, Ia3, Ia-3, Ia4, Ia-4, IAb, I-Ab, I-Abeta, I-Ad, I-Aq, I-E alpha MHC class II, I-E beta MHC class II, I-Ealpha, I-Ed, I-Ek, major histocompatibility complex class II beta chain, major histocompatibility complex H-2E beta chain, MHC class 2, MHC class II antigen A beta, MHC class II antigen E alpha, MHC class II H2-IA-beta-psi, MHC class II I
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Form:
Liquid