PIMA532271

Phospho-STAT1 (Ser727) Recombinant Rabbit Monoclonal Antibody (SN67-04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532271-Each-of-1 In Stock ₹ 45,646.26

PIMA532271 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

Phospho-STAT1 (Ser727)

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P42224, P42225

Gene Symbols

STAT1

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser727 of Human STAT1 aa 701-750

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

SN67-04

Conjugate

Unconjugated

Gene

STAT1

Gene Alias

2010005J02Rik, AA408197, CANDF7, DD6G4-4, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF-3, LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta, OTTHUMP00000165046, OTTHUMP00000205845, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT, STAT 1, STAT1, STAT-1, stat1 alpha, STAT91, transcription factor ISGF-3, transcription factor ISGF-3 components p91/p84

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

20846, 25124, 6772

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
  • STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
  • STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
  • Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
  • The STAT1 gene is located on chromosome 2
  • STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
  • After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
  • Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
  • STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
  • Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.

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Img

Thermo Scientific

PIMA532271

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Antigen:
Phospho-STAT1 (Ser727)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P42224, P42225

Gene Symbols:
STAT1

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser727 of Human STAT1 aa 701-750

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
SN67-04

Conjugate:
Unconjugated

Gene:
STAT1

Gene Alias:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF-3, LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta, OTTHUMP00000165046, OTTHUMP00000205845, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT, STAT 1, STAT1, STAT-1, stat1 alpha, STAT91, transcription factor ISGF-3, transcription factor ISGF-3 components p91/p84

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
20846, 25124, 6772

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532272

--


Antigen:
Nestin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P48681

Gene Symbols:
Nes

Immunogen:
Synthetic peptide within Human Nestin aa 531-580

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
SN06-27

Conjugate:
Unconjugated

Gene:
Nes

Gene Alias:
AA166324, C78523, ESTM46, FLJ21841, intermediate filament protein, Nbla00170, Nes, Nestin

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
10763

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532273

--


Antigen:
Phospho-SHP2 (Tyr542)

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P35235, Q06124

Gene Symbols:
PTPN11

Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr542 of Human SHP2 aa 511-560

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SN61-01

Conjugate:
Unconjugated

Gene:
PTPN11

Gene Alias:
2700084A17Rik, AW536184, bptp3, CFC, cSH-PTP2, encodes catalytic domain, HCP, HGNC:9644, JMML, METCDS, MGC14433, Noonan syndrome 1, ns1, null, OTTHUMP00000166108, phosphotyrosyl-protein phosphatase, protein tyrosine phosphatase non-receptor type 11, protein tyrosine phosphatase SH-PTP2, protein tyrosine phosphatase, non-receptor type 11, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), protein tyrosine phosphatase, non-receptor type 11 S homeolog, protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein-tyrosine phosphatase SYP, PTP1C, PTP1D, PTP-1D, ptp-2, PTP2C, PTP-2C, Ptpn11, ptpn11.S, ptpn11-a, ptpn11-b, SAP-2, SH2 domain-containing protein tyrosine phosphatase-2, Shp2, shp-2, SHPTP2, SH-PTP2, SH-PTP2 protein tyrosine phosphatase non-receptor type 11, SH-PTP2 protein tyrosine phosphatase, non-receptor type 11, SH-PTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11, XELAEV_18010676mg

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
19247, 5781

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532274

--


Antigen:
IKK alpha/beta

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O14920, O15111, O88351, Q60680, Q9QY78

Gene Symbols:
CHUK, Ikbkb

Immunogen:
Recombinant protein within Human IKK beta aa 450-652

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot, Western Blot

Clone:
SN63-02

Conjugate:
Unconjugated

Gene:
CHUK

Gene Alias:
AI132552, AI256658, AIM-1, CHUK, Chuk1, component of inhibitor of nuclear factor kappa B kinase complex, conserved helix-loop-helix ubiquitous kinase, EC 2.7.11.10, Fbx24, Fbxo24, I kappa B kinase 1, i kappa-B kinase alpha, IkappaB kinase, I-kappa-B kinase 1, I-kappa-B kinase 2, IkappaB kinase alpha, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, I-kappa-B-kinase beta, IkB kinase alpha subunit, IkB kinase-alpha, IkB kinase-beta, ikBKA, Ikbkb, IKK alpha, IKK[b], IKK1, IKK2, IKK-2, IKKA, IKK-A, IKK-a kinase, IKK-alpha, Ikkb, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa B kinase subunit beta, inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKA, NFKBIKB, Nuclear factor NFkappaB inhibitor kinase alpha, nuclear factor NF-kappa-B inhibitor kinase alpha, Nuclear factor NF-kappa-B inhibitor kinase beta, TCF16, TCF-16, TCF17, Transcription factor 16

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1147, 12675, 16150, 309361, 3551, 84351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid