PIMA532274
IKK alpha/beta Recombinant Rabbit Monoclonal Antibody (SN63-02), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532274-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA532274 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
IKK alpha/beta
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
O14920, O15111, O88351, Q60680, Q9QY78
Gene Symbols
CHUK, Ikbkb
Immunogen
Recombinant protein within Human IKK beta aa 450-652
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot, Western Blot
Clone
SN63-02
Conjugate
Unconjugated
Gene
CHUK
Gene Alias
AI132552, AI256658, AIM-1, CHUK, Chuk1, component of inhibitor of nuclear factor kappa B kinase complex, conserved helix-loop-helix ubiquitous kinase, EC 2.7.11.10, Fbx24, Fbxo24, I kappa B kinase 1, i kappa-B kinase alpha, IkappaB kinase, I-kappa-B kinase 1, I-kappa-B kinase 2, IkappaB kinase alpha, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, I-kappa-B-kinase beta, IkB kinase alpha subunit, IkB kinase-alpha, IkB kinase-beta, ikBKA, Ikbkb, IKK alpha, IKK[b], IKK1, IKK2, IKK-2, IKKA, IKK-A, IKK-a kinase, IKK-alpha, Ikkb, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa B kinase subunit beta, inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKA, NFKBIKB, Nuclear factor NFkappaB inhibitor kinase alpha, nuclear factor NF-kappa-B inhibitor kinase alpha, Nuclear factor NF-kappa-B inhibitor kinase beta, TCF16, TCF-16, TCF17, Transcription factor 16
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
1147, 12675, 16150, 309361, 3551, 84351
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- IKK alpha/beta is encoded by CHUK (conserved helix-loop-helix ubiquitous kinase) and IKKB (inhibitor of kappa light polypeptide gene enhancer in B-cells) gene located in chromosome 10 and 8 respectively in humans
- Upon stimulation by agents that activate the NF-kB pathway such as TNF alpha, the two subunits of IKK complex, IKK alpha and IKK -beta alongside a regulator NEMO (IKK gamma) phosphorylates IkB proteins
- This targets the later for ubiquitin mediated degradation and phosphorylation of NF-kB leading to subsequent translocation to the nucleus
- Phosphorylation at serine 176 and 180 located in the activation loop causes a confirmation change that is required for the activation of the kinases.
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Antigen: IKK alpha/beta
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O14920, O15111, O88351, Q60680, Q9QY78
Gene Symbols: CHUK, Ikbkb
Immunogen: Recombinant protein within Human IKK beta aa 450-652
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: SN63-02
Conjugate: Unconjugated
Gene: CHUK
Gene Alias: AI132552, AI256658, AIM-1, CHUK, Chuk1, component of inhibitor of nuclear factor kappa B kinase complex, conserved helix-loop-helix ubiquitous kinase, EC 2.7.11.10, Fbx24, Fbxo24, I kappa B kinase 1, i kappa-B kinase alpha, IkappaB kinase, I-kappa-B kinase 1, I-kappa-B kinase 2, IkappaB kinase alpha, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, I-kappa-B-kinase beta, IkB kinase alpha subunit, IkB kinase-alpha, IkB kinase-beta, ikBKA, Ikbkb, IKK alpha, IKK[b], IKK1, IKK2, IKK-2, IKKA, IKK-A, IKK-a kinase, IKK-alpha, Ikkb, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa B kinase subunit beta, inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKA, NFKBIKB, Nuclear factor NFkappaB inhibitor kinase alpha, nuclear factor NF-kappa-B inhibitor kinase alpha, Nuclear factor NF-kappa-B inhibitor kinase beta, TCF16, TCF-16, TCF17, Transcription factor 16
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1147, 12675, 16150, 309361, 3551, 84351
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
IKK alpha/beta
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O14920, O15111, O88351, Q60680, Q9QY78
Gene Symbols:
CHUK, Ikbkb
Immunogen:
Recombinant protein within Human IKK beta aa 450-652
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
SN63-02
Conjugate:
Unconjugated
Gene:
CHUK
Gene Alias:
AI132552, AI256658, AIM-1, CHUK, Chuk1, component of inhibitor of nuclear factor kappa B kinase complex, conserved helix-loop-helix ubiquitous kinase, EC 2.7.11.10, Fbx24, Fbxo24, I kappa B kinase 1, i kappa-B kinase alpha, IkappaB kinase, I-kappa-B kinase 1, I-kappa-B kinase 2, IkappaB kinase alpha, I-kappa-B kinase alpha, I-kappa-B kinase-alpha, I-kappa-B-kinase beta, IkB kinase alpha subunit, IkB kinase-alpha, IkB kinase-beta, ikBKA, Ikbkb, IKK alpha, IKK[b], IKK1, IKK2, IKK-2, IKKA, IKK-A, IKK-a kinase, IKK-alpha, Ikkb, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa B kinase subunit beta, inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, NFKBIKA, NFKBIKB, Nuclear factor NFkappaB inhibitor kinase alpha, nuclear factor NF-kappa-B inhibitor kinase alpha, Nuclear factor NF-kappa-B inhibitor kinase beta, TCF16, TCF-16, TCF17, Transcription factor 16
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1147, 12675, 16150, 309361, 3551, 84351
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-c-Myc (Thr58)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P01106
Gene Symbols: MYC
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Thr58 of Human Myc aa 30-79
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone: SN60-01
Conjugate: Unconjugated
Gene: MYC
Gene Alias: AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4609
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-c-Myc (Thr58)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P01106
Gene Symbols:
MYC
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Thr58 of Human Myc aa 30-79
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone:
SN60-01
Conjugate:
Unconjugated
Gene:
MYC
Gene Alias:
AU016757, Avian myelocytomatosis viral (v-myc) oncogene homolog, avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, class E basic helix-loop-helix protein 39, cmyc, c-Myc, c-myc epitope tag, c-myc proto-oncogene, mMyc, MRTL, Myc, Myc protein, Myc proto-oncogene protein, MYC proto-oncogene, bHLH transcription factor, Myc2, MYCC, myc-related translation/localization regulatory factor, myelocytomatosis oncogene, myelocytomatosis viral oncogene homolog, Niard, Nird, Proto-oncogene c-Myc, RNCMYC, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene-like protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4609
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PLCG1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P10686, P19174, Q62077
Gene Symbols: PLCG1
Immunogen: Recombinant protein within Human Phospholipase C gamma 1 aa 690-852
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: SN06-10
Conjugate: Unconjugated
Gene: PLCG1
Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, AI894140, Cded, cell differentiation and embryonic development, EC 3.1.4.11, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, NCKAP3, OTTHUMP00000178982, phosphatidylinositol phospholipase C, phosphoinositidase C, phosphoinositide phospholipase C, phosphoinositide phospholipase C-gamma-1, phospholipase C gamma 1, phospholipase C, gamma 1, phospholipase C, gamma 1 (formerly subtype 148), phospholipase C-1, phospholipase C-148, Phospholipase C2, phospholipase C-gamma-1, Phospholipase C-II, PLC gamma1, PLC1, Plc-1, PLC148, PLC-148, PLC2I, Plcg1, Plcg-1, PLCgamma1, Plc-gamma1, PLC-gamma-1, PLC-II, PPLCA, triphosphoinositide phosphodiesterase
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18803, 25738, 5335
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PLCG1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P10686, P19174, Q62077
Gene Symbols:
PLCG1
Immunogen:
Recombinant protein within Human Phospholipase C gamma 1 aa 690-852
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
SN06-10
Conjugate:
Unconjugated
Gene:
PLCG1
Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1, AI894140, Cded, cell differentiation and embryonic development, EC 3.1.4.11, inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, NCKAP3, OTTHUMP00000178982, phosphatidylinositol phospholipase C, phosphoinositidase C, phosphoinositide phospholipase C, phosphoinositide phospholipase C-gamma-1, phospholipase C gamma 1, phospholipase C, gamma 1, phospholipase C, gamma 1 (formerly subtype 148), phospholipase C-1, phospholipase C-148, Phospholipase C2, phospholipase C-gamma-1, Phospholipase C-II, PLC gamma1, PLC1, Plc-1, PLC148, PLC-148, PLC2I, Plcg1, Plcg-1, PLCgamma1, Plc-gamma1, PLC-gamma-1, PLC-II, PPLCA, triphosphoinositide phosphodiesterase
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18803, 25738, 5335
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-Synapsin 1 (Ser9)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: O88935, P09951, P17600
Gene Symbols: SYN1
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser9 of Human Synapsin I aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry, Western Blot
Clone: SN63-04
Conjugate: Unconjugated
Gene: SYN1
Gene Alias: Brain protein 4.1, SYN1, Syn-1, SYN1a, SYN1b, Syn1-S, synapsin 1, synapsin I, synapsin Ia, synapsin Ib, synapsin-1, SYNI, truncated synapsin 1-S
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 20964, 24949, 6853
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-Synapsin 1 (Ser9)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
O88935, P09951, P17600
Gene Symbols:
SYN1
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser9 of Human Synapsin I aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry, Western Blot
Clone:
SN63-04
Conjugate:
Unconjugated
Gene:
SYN1
Gene Alias:
Brain protein 4.1, SYN1, Syn-1, SYN1a, SYN1b, Syn1-S, synapsin 1, synapsin I, synapsin Ia, synapsin Ib, synapsin-1, SYNI, truncated synapsin 1-S
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
20964, 24949, 6853
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid