PIMA532807

IKK epsilon Recombinant Rabbit Monoclonal Antibody (JU06-72), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532807-Each-of-1 In Stock ₹ 44,619.54

PIMA532807 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

IKK epsilon

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q14164, Q9R0T8

Gene Symbols

IKBKE

Immunogen

Synthetic peptide within Human IKBKE aa 26-75

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

JU06-72

Conjugate

Unconjugated

Gene

IKBKE

Gene Alias

AW558201, I-kappa-B kinase epsilon, Ikbke, IKKE, IKK-E, IKKepsilon, IKK-epsilon, IKKI, IKK-i, IKK-related kinase epsilon, inducible I kappa-B kinase, inducible IkappaB kinase, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon, inhibitor of kappaB kinase epsilon, inhibitor of nuclear factor kappa-B kinase subunit epsilon, KIAA0151, RP11-534L20.1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

56489, 9641

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • IKBKE is an activator of nuclear factor-kappa-B
  • Over expression of IKBKE has been observed in breast cancer cells, and suppression of IKBKE induces cell death
  • NF-kappa-B is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
  • NF-kappa-B mediates the expression of a great variety of genes in response to extracellular stimuli
  • NF-kappa-B is associated with Ikappa-B proteins in the cell cytoplasm, which inhibit NF-kappa-B activity
  • Ikappa-B is phosphorylated by Ikappa-B kinase (IKK) complex that contains IKK-a, IKK-b, and IKK-gamma
  • A novel molecule in the IKK complex was recently identified and designated IKK-iota/IKK-i
  • IKK epsilon is required for the activation of NF-kappa-B by PMA and T cell receptors but not by TNF-a and IL-1
  • IKK-iota/IKK-i message is expressed in a variety of tissues and is inducible by TNF-a, IL-1, and LPS.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532807

--


Antigen:
IKK epsilon

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q14164, Q9R0T8

Gene Symbols:
IKBKE

Immunogen:
Synthetic peptide within Human IKBKE aa 26-75

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JU06-72

Conjugate:
Unconjugated

Gene:
IKBKE

Gene Alias:
AW558201, I-kappa-B kinase epsilon, Ikbke, IKKE, IKK-E, IKKepsilon, IKK-epsilon, IKKI, IKK-i, IKK-related kinase epsilon, inducible I kappa-B kinase, inducible IkappaB kinase, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon, inhibitor of kappaB kinase epsilon, inhibitor of nuclear factor kappa-B kinase subunit epsilon, KIAA0151, RP11-534L20.1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
56489, 9641

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532808

--


Antigen:
DDB1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q16531, Q3U1J4, Q9ESW0

Gene Symbols:
DDB1

Immunogen:
Recombinant protein within Human DDB1 aa 1040-1140

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot, Western Blot

Clone:
JU32-35

Conjugate:
Unconjugated

Gene:
DDB1

Gene Alias:
127kDa, AA408517, damage specific DNA binding protein 1, damaged-DNA recognition protein 1, damage-specific DNA binding protein 1, 127kDa, damage-specific DNA-binding protein 1, damage-specific DNA-binding protein, DNA repair, DDB p127 subunit, DDB1, DDBa, DNA damage-binding protein 1, DNA damage-binding protein a, DNA repair protein, HBV X-associated protein 1, p127-Ddb1, UV-damaged DNA-binding factor, UV-damaged DNA-binding protein 1, UV-DDB 1, UV-DDB1, XAP1, XAP-1, xeroderma pigmento, Xeroderma pigmentosum group E-complementing protein, XPCE, XPE, XPE-BF, XPE-binding factor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13194, 1642, 64470

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532809

--


Antigen:
alpha Internexin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P23565, P46660, Q16352

Gene Symbols:
INA

Immunogen:
Synthetic peptide within Human alpha Internexin aa 394-443

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JU25-03

Conjugate:
Unconjugated

Gene:
INA

Gene Alias:
66 kDa neurofilament protein, Alpha-internexin, alpha-Inx, AV028420, FLJ18662, FLJ57501, Ina, Inexa, internexin neuronal intermediate filament protein alpha, internexin neuronal intermediate filament protein, alpha, internexin, alpha, Intlaa, LOW QUALITY PROTEIN: alpha-internexin, MGC12702, NEF5, Neuro, Neurofilament 5, neurofilament 5 (66kD), Neurofilament 66, neurofilament-66, neurofilament-66, tax-binding protein, Nf66, NF-66, TXBP-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
226180, 24503, 9118

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532810

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Antigen:
SAMHD1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q9Y3Z3

Gene Symbols:
SAMHD1

Immunogen:
Synthetic peptide within Human SAMHD1 aa 577-626

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
JU56-04

Conjugate:
Unconjugated

Gene:
SAMHD1

Gene Alias:
CHBL2, DCIP, Dendritic cell-derived IFNG-induced protein, deoxynucleoside triphosphate triphosphohydrolase SAMHD1, dNTPase, E330031J07Rik, EGK_02438, HDDC1, hSAMHD1, IFN-gamma induced, interferon-gamma-inducible protein Mg11, Mg11, Mg21, Monocyte protein 5, MOP5, MOP-5, mSAMHD1, RP1-132F21.1, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1, SAM domain and HD domain 1, SAM domain and HD domain, 1, SAM domain and HD domain-containing protein 1, Samhd1, SBBI88

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25939

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid