PIMA533067

NFkB p50/p105 Recombinant Rabbit Monoclonal Antibody (RM299), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533067-Each-of-1 In Stock ₹ 45,646.26

PIMA533067 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

NFkB p50/p105

Classification

Recombinant Monoclonal

Concentration

0.1 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P19838

Gene Symbols

NFKB1

Immunogen

A peptide corresponding to residues in the human NFkappa-B p105 subunit and p50 subunit.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM299

Conjugate

Unconjugated

Gene

NFKB1

Gene Alias

CVID12, DKFZp686C01211, DNA-binding factor KBF1, EBP-1, KBF1, MGC54151, NF kappaB1, NF KB, NFkappaB, NF-kappaB, NF-kappa-B, NF-kappaB p50, NF-kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappabeta, NF-kB, NFKB1, NF-KB1, NFKB-p105, NFKB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 1, nuclear factor kappa-B DNA binding subunit, nuclear factor kappaB p50, nuclear factor NF-kappa-B p105 subunit, Nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, nuclear factor-kappaB p50, p105, p50, p50 subunit of NF kappaB, p50 subunit of NF-kappaB, p50/p105

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4790

Content And Storage

-20°C

Form

Liquid

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Description

  • Specificity: reacts to human nuclear factor NF-kappaB p105 subunit and p50 subunit
  • It may also react to mouse or rat NF-kappa-B p105/p50, as predicted by immunogen homology
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products
  • It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation
  • NFKB1 (p50), a 50KDa functional sub-unit of NF-kB, is a member of Rel protein family
  • It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains
  • NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor
  • NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-bidning
  • Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.

Compare Similar Items

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Img

Thermo Scientific

PIMA533067

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Antigen:
NFkB p50/p105

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P19838

Gene Symbols:
NFKB1

Immunogen:
A peptide corresponding to residues in the human NFkappa-B p105 subunit and p50 subunit.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM299

Conjugate:
Unconjugated

Gene:
NFKB1

Gene Alias:
CVID12, DKFZp686C01211, DNA-binding factor KBF1, EBP-1, KBF1, MGC54151, NF kappaB1, NF KB, NFkappaB, NF-kappaB, NF-kappa-B, NF-kappaB p50, NF-kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappabeta, NF-kB, NFKB1, NF-KB1, NFKB-p105, NFKB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 1, nuclear factor kappa-B DNA binding subunit, nuclear factor kappaB p50, nuclear factor NF-kappa-B p105 subunit, Nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, nuclear factor-kappaB p50, p105, p50, p50 subunit of NF kappaB, p50 subunit of NF-kappaB, p50/p105

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4790

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533068

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Antigen:
CD21

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P20023

Gene Symbols:
CR2

Immunogen:
A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM372

Conjugate:
Unconjugated

Gene:
CR2

Gene Alias:
C3b/C4b receptor, C3-binding protein, C3BR, C3DR, C4BR, CD21, CD35, CD35 antigen, cell surface receptor for C3d, complement C3b/C4b receptor 1 (Knops blood group), complement C3d receptor, Complement C3d receptor (C3DR), complement C3d receptor 2, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3d/Epstein Barr virus) receptor 2, complement component 3b/4b receptor 1 (Knops blood group), complement component 3d receptor 2, complement component receptor 2, complement receptor 1 long isoform, complement receptor 2, complement receptor type 1, complement receptor type 1-like protein, complement receptor type 2, Complement Receptor type 2 (CR2), CR, CR1, Cr-1, CR1-L, Cr2, Cr-2, CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, expressed in B lymphocytes, KN, Knops blood group antigen, LOW QUALITY PROTEIN: complement receptor type 1, SLEB9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1380

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533069

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Antigen:
AKT1 (E17K Mutant)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P31749

Gene Symbols:
AKT1

Immunogen:
A peptide corresponding to Akt E17K mutant.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
RM336

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
207

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533070

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Antigen:
AKT1 (PH domain)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P31749

Gene Symbols:
AKT1

Immunogen:
A peptide corresponding to the PH domain of human AKT.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM316

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
207

Content And Storage:
-20°C

Form:
Liquid