PIMA533068

CD21 Recombinant Rabbit Monoclonal Antibody (RM372), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA533068-Each-of-1 In Stock ₹ 46,159.62

PIMA533068 - Each of 1

₹ 46,159.62

In Stock

Quantity

1

Base Price: ₹ 46,159.62

GST (18%): ₹ 8,308.732

Total Price: ₹ 54,468.352

Antigen

CD21

Classification

Recombinant Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P20023

Gene Symbols

CR2

Immunogen

A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM372

Conjugate

Unconjugated

Gene

CR2

Gene Alias

C3b/C4b receptor, C3-binding protein, C3BR, C3DR, C4BR, CD21, CD35, CD35 antigen, cell surface receptor for C3d, complement C3b/C4b receptor 1 (Knops blood group), complement C3d receptor, Complement C3d receptor (C3DR), complement C3d receptor 2, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3d/Epstein Barr virus) receptor 2, complement component 3b/4b receptor 1 (Knops blood group), complement component 3d receptor 2, complement component receptor 2, complement receptor 1 long isoform, complement receptor 2, complement receptor type 1, complement receptor type 1-like protein, complement receptor type 2, Complement Receptor type 2 (CR2), CR, CR1, Cr-1, CR1-L, Cr2, Cr-2, CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, expressed in B lymphocytes, KN, Knops blood group antigen, LOW QUALITY PROTEIN: complement receptor type 1, SLEB9

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1380

Content And Storage

-20°C

Form

Liquid

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Description

  • Specificity: reacts to human CD21 (Complement receptor type 2)
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • CD21 (complement receptor 2, CR2, C3D receptor, EBV receptor) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen
  • CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens
  • CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to follicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions
  • A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands
  • CD21 functions as receptor for C3d, C3dg and iC3b complement components, for EBV and for IFNalpha
  • CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation
  • Genetic variations in the CD21 gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9)
  • Alternatively, spliced transcript variants encoding different isoforms of CD21 have been found.

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Thermo Scientific

PIMA533068

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Antigen:
CD21

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P20023

Gene Symbols:
CR2

Immunogen:
A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM372

Conjugate:
Unconjugated

Gene:
CR2

Gene Alias:
C3b/C4b receptor, C3-binding protein, C3BR, C3DR, C4BR, CD21, CD35, CD35 antigen, cell surface receptor for C3d, complement C3b/C4b receptor 1 (Knops blood group), complement C3d receptor, Complement C3d receptor (C3DR), complement C3d receptor 2, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3d/Epstein Barr virus) receptor 2, complement component 3b/4b receptor 1 (Knops blood group), complement component 3d receptor 2, complement component receptor 2, complement receptor 1 long isoform, complement receptor 2, complement receptor type 1, complement receptor type 1-like protein, complement receptor type 2, Complement Receptor type 2 (CR2), CR, CR1, Cr-1, CR1-L, Cr2, Cr-2, CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, expressed in B lymphocytes, KN, Knops blood group antigen, LOW QUALITY PROTEIN: complement receptor type 1, SLEB9

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1380

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533069

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Antigen:
AKT1 (E17K Mutant)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P31749

Gene Symbols:
AKT1

Immunogen:
A peptide corresponding to Akt E17K mutant.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
RM336

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
207

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533070

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Antigen:
AKT1 (PH domain)

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P31749

Gene Symbols:
AKT1

Immunogen:
A peptide corresponding to the PH domain of human AKT.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM316

Conjugate:
Unconjugated

Gene:
AKT1

Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
207

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533072

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Antigen:
MMP12

Classification:
Recombinant Monoclonal

Concentration:
0.05 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P39900

Gene Symbols:
Mmp12

Immunogen:
A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM381

Conjugate:
Unconjugated

Gene:
Mmp12

Gene Alias:
3.4.24.65, AV378681, HME, Macrophage elastase, macrophage metalloelastase, macrophage-metalloelastase, matrix metallo protease, matrix metallopeptidase 12, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12, matrix metalloproteinase 12 (macrophage elastase), matrix metalloproteinase-12, ME, MGC138506, MME, Mmel, MMP, Mmp12, MMP-12, MMPs

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4321

Content And Storage:
-20°C

Form:
Liquid