PIMA533072

MMP12 Recombinant Rabbit Monoclonal Antibody (RM381), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA533072-Each-of-1 In Stock ₹ 45,646.26

PIMA533072 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

MMP12

Classification

Recombinant Monoclonal

Concentration

0.05 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

P39900

Gene Symbols

Mmp12

Immunogen

A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM381

Conjugate

Unconjugated

Gene

Mmp12

Gene Alias

3.4.24.65, AV378681, HME, Macrophage elastase, macrophage metalloelastase, macrophage-metalloelastase, matrix metallo protease, matrix metallopeptidase 12, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12, matrix metalloproteinase 12 (macrophage elastase), matrix metalloproteinase-12, ME, MGC138506, MME, Mmel, MMP, Mmp12, MMP-12, MMPs

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4321

Content And Storage

-20°C

Form

Liquid

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Description

  • Specificity: reacts to human Matrix metalloproteinase-12 (MMP-12)
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis
  • Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases
  • It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described
  • The enzyme degrades soluble and insoluble elastin
  • It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema
  • The gene is part of a cluster of MMP genes which localize to chromosome 11q22
  • 3.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA533072

--


Antigen:
MMP12

Classification:
Recombinant Monoclonal

Concentration:
0.05 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P39900

Gene Symbols:
Mmp12

Immunogen:
A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM381

Conjugate:
Unconjugated

Gene:
Mmp12

Gene Alias:
3.4.24.65, AV378681, HME, Macrophage elastase, macrophage metalloelastase, macrophage-metalloelastase, matrix metallo protease, matrix metallopeptidase 12, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12, matrix metalloproteinase 12 (macrophage elastase), matrix metalloproteinase-12, ME, MGC138506, MME, Mmel, MMP, Mmp12, MMP-12, MMPs

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4321

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533074

--


Antigen:
Nkx2.1

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P43699

Gene Symbols:
NKX2-1

Immunogen:
A peptide corresponding to the N-terminus of human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM373

Conjugate:
Unconjugated

Gene:
NKX2-1

Gene Alias:
AV026640, BCH, BHC, homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NK-2, NK2 homeobox 1, NK-2 homolog A, NKX2.1, Nkx-2.1, NKX2-1, NKX2A, NMTC1, RNA polymerase I transcription termination factor, T/EBP, TEBP, Thyroid nuclear factor 1, thyroid transcription factor 1, thyroid transcription factor 1 TTF-1 NK-2, thyroid transcription factor 1-like, thyroid-specific enhancer-binding protein, tinman, TITF1, TTF1, TTF-1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
7080

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533075

--


Antigen:
Paxillin

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P49023

Gene Symbols:
PXN

Immunogen:
A peptide corresponding to the N-terminus of human Paxillin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
RM256

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein, AW108311, AW123232, FLJ16691, hCG_1778014, I79_001229, myocardial ischemic preconditioning associated protein 7, Pax, PAX-1, PAXI, Paxillin, paxillin a, paxillin alpha, pxn, pxna, testicular tissue protein Li 134, TGFB1I1, transforming growth factor beta 1 induced transcript 1, wu:fw71f12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5829

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533076

--


Antigen:
MSH6

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P52701

Gene Symbols:
MSH6

Immunogen:
Mammalian cell expressed recombinant protein fragment of human MSH6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot

Clone:
RM376

Conjugate:
Unconjugated

Gene:
MSH6

Gene Alias:
AU044881, AW550279, cb326, DNA mismatch repair protein Msh6, g/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, LOC100360342, mismatch repair protein Msh6, Msh6, mutS (E. coli) homolog 6, MutS alpha 160kDa subunit, mutS homolog 6, mutS homolog 6 (E. coli), MutS protein homolog 6, MutS-alpha 160 kDa subunit, MutS-alpha 160kDa subunit, p160, rCG61559-like, Sperm associated protein, sperm-associated protein, wu:fb36c12

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2956

Content And Storage:
-20°C

Form:
Liquid