PIMA533093
ALK Recombinant Rabbit Monoclonal Antibody (RM361), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533093-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA533093 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
ALK
Classification
Recombinant Monoclonal
Concentration
0.1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
Q9UM73
Gene Symbols
ALK
Immunogen
A peptide corresponding to the C-terminus of human ALK (Anaplastic lymphoma kinase).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
RM361
Conjugate
Unconjugated
Gene
ALK
Gene Alias
Alk, ALK tyrosine kinase receptor, ALK/NPM1 fusion gene, anaplastic lymphoma kinase, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, CD246 antigen, EC 2.7.10.1, kinase ALK, mutant anaplastic lymphoma kinase, NBLST3, npm-alk, p80, Tcrz, TFG/ALK
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
238
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human total ALK protein including ALK fusion proteins
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily
- It is vital for brain development
- Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors, including anaplastic large cell lymphoma, neurblastoma, and non-small cell lung cancer
- Chromosomal rearrangement is the most common genetic alteration
- The translocation creates a fusion gene consisting of the ALK gene and the nucleophosmin gene: the 3' half of ALK, derived from chromosome 2, is fused to the 5' portion of NPM from chromosome 5
- A recent study shows that the product of the NPM-ALK fusion gene is oncogenic
- The deduced amino acid sequences reveal that ALK is a novel receptor protein-tyrosine kinase having a putative transmembrane domain and an extracellular domain
- These sequences are absent in the product of the transforming NPM-ALK gene
- ALK shows the greatest sequence similarity to LTK
- ALK plays an important role in the development of the brain and exerts its effects on specific neurons in the nervous system.
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Antigen: ALK
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: Q9UM73
Gene Symbols: ALK
Immunogen: A peptide corresponding to the C-terminus of human ALK (Anaplastic lymphoma kinase).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM361
Conjugate: Unconjugated
Gene: ALK
Gene Alias: Alk, ALK tyrosine kinase receptor, ALK/NPM1 fusion gene, anaplastic lymphoma kinase, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, CD246 antigen, EC 2.7.10.1, kinase ALK, mutant anaplastic lymphoma kinase, NBLST3, npm-alk, p80, Tcrz, TFG/ALK
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 238
Content And Storage: -20°C
Form: Liquid
Antigen:
ALK
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
Q9UM73
Gene Symbols:
ALK
Immunogen:
A peptide corresponding to the C-terminus of human ALK (Anaplastic lymphoma kinase).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM361
Conjugate:
Unconjugated
Gene:
ALK
Gene Alias:
Alk, ALK tyrosine kinase receptor, ALK/NPM1 fusion gene, anaplastic lymphoma kinase, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, CD246 antigen, EC 2.7.10.1, kinase ALK, mutant anaplastic lymphoma kinase, NBLST3, npm-alk, p80, Tcrz, TFG/ALK
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
238
Content And Storage:
-20°C
Form:
Liquid
Antigen: SATB2
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: Q9UPW6
Gene Symbols: SATB2
Immunogen: A peptide corresponding to the C-terminus of human DNA-binding protein SATB2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM365
Conjugate: Unconjugated
Gene: SATB2
Gene Alias: DNA-binding protein SATB2, FLJ21474, FLJ32076, GLSS, KIAA1034, KIAA1034-like DNA binding protein, MGC119474, MGC119477, mKIAA1034, RGD1562369, SATB family member 2, SATB homeobox 2, SATB2, special AT-rich sequence binding protein 2, special AT-rich sequence-binding protein 2, two cut domains-containing homeodomain protein
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 23314
Content And Storage: -20°C
Form: Liquid
Antigen:
SATB2
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
Q9UPW6
Gene Symbols:
SATB2
Immunogen:
A peptide corresponding to the C-terminus of human DNA-binding protein SATB2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM365
Conjugate:
Unconjugated
Gene:
SATB2
Gene Alias:
DNA-binding protein SATB2, FLJ21474, FLJ32076, GLSS, KIAA1034, KIAA1034-like DNA binding protein, MGC119474, MGC119477, mKIAA1034, RGD1562369, SATB family member 2, SATB homeobox 2, SATB2, special AT-rich sequence binding protein 2, special AT-rich sequence-binding protein 2, two cut domains-containing homeodomain protein
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
23314
Content And Storage:
-20°C
Form:
Liquid
Antigen: ABCA4
Classification: Monoclonal
Concentration: ∽1 mg/mL
Formulation: 10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5
Gene Accession No.: O35600, P78363
Gene Symbols: ABCA4, abca4.L
Immunogen: Partially purified bovine 220-kDa disc rim protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, X. laevis
Product Type: Antibody
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: 3F4
Conjugate: Unconjugated
Gene: ABCA4
Gene Alias: ABC transporter, ABC10, abca4, abca4.L, Abcr, ARMD2, ATP binding cassette subfamily A member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP binding cassette transporter, ATP-binding cassette 10, ATP-binding cassette sub-family A member 4, ATP-binding cassette transporter, retinal-specific, ATP-binding cassette, subfamily A (ABC1), member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP-binding cassette, sub-family A, member 4, ATP-binding transporter, retina-specific, AW050280, CORD3, D430003I15Rik, FFM, photoreceptor rim protein, retinal ABCA4 transporter, retinal-specific ATP-binding cassette transporter, Retinal-specific phospholipid-transporting ATPase ABCA4, retina-specific ABC transporter, RIM ABC transporter, RIM protein, RMP, RP19, Stargardt disease protein, STGD, STGD1, XELAEV_180233141mg
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11304, 24, 281584, 497268
Content And Storage: -20°, C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ABCA4
Classification:
Monoclonal
Concentration:
∽1 mg/mL
Formulation:
10mM HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative, pH 7.5
Gene Accession No.:
O35600, P78363
Gene Symbols:
ABCA4, abca4.L
Immunogen:
Partially purified bovine 220-kDa disc rim protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, X. laevis
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
3F4
Conjugate:
Unconjugated
Gene:
ABCA4
Gene Alias:
ABC transporter, ABC10, abca4, abca4.L, Abcr, ARMD2, ATP binding cassette subfamily A member 4, ATP binding cassette subfamily A member 4 L homeolog, ATP binding cassette transporter, ATP-binding cassette 10, ATP-binding cassette sub-family A member 4, ATP-binding cassette transporter, retinal-specific, ATP-binding cassette, subfamily A (ABC1), member 4, ATP-binding cassette, sub-family A (ABC1), member 4, ATP-binding cassette, sub-family A, member 4, ATP-binding transporter, retina-specific, AW050280, CORD3, D430003I15Rik, FFM, photoreceptor rim protein, retinal ABCA4 transporter, retinal-specific ATP-binding cassette transporter, Retinal-specific phospholipid-transporting ATPase ABCA4, retina-specific ABC transporter, RIM ABC transporter, RIM protein, RMP, RP19, Stargardt disease protein, STGD, STGD1, XELAEV_180233141mg
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11304, 24, 281584, 497268
Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MECP2
Classification: Monoclonal
Concentration: ∽1 mg/mL
Formulation: PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.: P51608, Q00566, Q9Z2D6
Gene Symbols: Mecp2
Immunogen: Full length human recombinant MeCP2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG2b
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 5H12
Conjugate: Unconjugated
Gene: Mecp2
Gene Alias: 1500041B07Rik, AUTSX3, D630021H01Rik, DKFZp686A24160, Mbd5, MECP2, MeCp-2 protein, methyl CpG binding protein 2, methyl-CpG binding protein 2, methyl-CpG-binding protein 2, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, testis tissue sperm-binding protein Li 41a, WBP10
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17257, 29386, 4204
Content And Storage: -20°, C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MECP2
Classification:
Monoclonal
Concentration:
∽1 mg/mL
Formulation:
PBS with 50% glycerol and 5mM sodium azide
Gene Accession No.:
P51608, Q00566, Q9Z2D6
Gene Symbols:
Mecp2
Immunogen:
Full length human recombinant MeCP2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
5H12
Conjugate:
Unconjugated
Gene:
Mecp2
Gene Alias:
1500041B07Rik, AUTSX3, D630021H01Rik, DKFZp686A24160, Mbd5, MECP2, MeCp-2 protein, methyl CpG binding protein 2, methyl-CpG binding protein 2, methyl-CpG-binding protein 2, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, testis tissue sperm-binding protein Li 41a, WBP10
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17257, 29386, 4204
Content And Storage:
-20°, C, Avoid Freeze/Thaw Cycles
Form:
Liquid