PIMA533051
Androgen Receptor Recombinant Rabbit Monoclonal Antibody (RM254), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533051-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA533051 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Androgen Receptor
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P10275
Gene Symbols
AR
Immunogen
A peptide corresponding to the N-terminus of Androgen Receptor.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
RM254
Conjugate
Unconjugated
Gene
AR
Gene Alias
AIS, Andr, androgen nuclear receptor variant 2, androgen receptor, androgen receptor (Testicular feminization), same as Tfm, androgen receptor splice variant 4b, Ar, AR8, AR-A, AW320017, DHTR, dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4, RP11-383C12.1, SBMA, SMAX1, TFM, Variant AR45
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
367
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to full length androgen receptor and splice variants
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors
- The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain
- The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT)
- Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes
- The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis
- AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain
- Androgen Receptor is a phosphoprotein, and also regulates mitogen-activated protein kinase (MAP kinase)
- The inhibition of the MEK1/2 pathway correlates directly with a change in phosphorylation state of the androgen receptor
- Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease, and male infertility
- Mutations in this gene are associated with complete androgen insensitivity (CAIS).
Compare Similar Items
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Antigen: Androgen Receptor
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P10275
Gene Symbols: AR
Immunogen: A peptide corresponding to the N-terminus of Androgen Receptor.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM254
Conjugate: Unconjugated
Gene: AR
Gene Alias: AIS, Andr, androgen nuclear receptor variant 2, androgen receptor, androgen receptor (Testicular feminization), same as Tfm, androgen receptor splice variant 4b, Ar, AR8, AR-A, AW320017, DHTR, dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4, RP11-383C12.1, SBMA, SMAX1, TFM, Variant AR45
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 367
Content And Storage: -20°C
Form: Liquid
Antigen:
Androgen Receptor
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P10275
Gene Symbols:
AR
Immunogen:
A peptide corresponding to the N-terminus of Androgen Receptor.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM254
Conjugate:
Unconjugated
Gene:
AR
Gene Alias:
AIS, Andr, androgen nuclear receptor variant 2, androgen receptor, androgen receptor (Testicular feminization), same as Tfm, androgen receptor splice variant 4b, Ar, AR8, AR-A, AW320017, DHTR, dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, Nuclear receptor subfamily 3 group C member 4, RP11-383C12.1, SBMA, SMAX1, TFM, Variant AR45
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
367
Content And Storage:
-20°C
Form:
Liquid
Antigen: Chromogranin A
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P10645
Gene Symbols: Chga
Immunogen: A peptide corresponding to the N-terminus of human Chromogranin A.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM385
Conjugate: Unconjugated
Gene: Chga
Gene Alias: AL-11, AL26, Beta-granin, betagranin (N-terminal fragment of chromogranin A), catestatin, CgA, CHGA, ChrA, chromofungin, chromogranin A, chromogranin A (parathyroid secretory protein 1), chromogranin A precursor, chromogranin-A, CTNNB, DKFZp686D02253, EA-92, ER-37, ES-43, FLJ25606, FLJ37923, GE-25, GR-44, GV-19, LF-19, LOW QUALITY PROTEIN: chromogranin-A, MGC105435, Pancreastatin, Parastatin, parathyroid secretory protein 1, p-Glu serpinin precursor, pituitary secretory protein I, Serpinin, Serpinin-RRG, SL21, SP-I, SS-18, Vasostatin I, Vasostatin II, Vasostatin-1, Vasostatin-2, WA-8, WE-14
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1113
Content And Storage: -20°C
Form: Liquid
Antigen:
Chromogranin A
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P10645
Gene Symbols:
Chga
Immunogen:
A peptide corresponding to the N-terminus of human Chromogranin A.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM385
Conjugate:
Unconjugated
Gene:
Chga
Gene Alias:
AL-11, AL26, Beta-granin, betagranin (N-terminal fragment of chromogranin A), catestatin, CgA, CHGA, ChrA, chromofungin, chromogranin A, chromogranin A (parathyroid secretory protein 1), chromogranin A precursor, chromogranin-A, CTNNB, DKFZp686D02253, EA-92, ER-37, ES-43, FLJ25606, FLJ37923, GE-25, GR-44, GV-19, LF-19, LOW QUALITY PROTEIN: chromogranin-A, MGC105435, Pancreastatin, Parastatin, parathyroid secretory protein 1, p-Glu serpinin precursor, pituitary secretory protein I, Serpinin, Serpinin-RRG, SL21, SP-I, SS-18, Vasostatin I, Vasostatin II, Vasostatin-1, Vasostatin-2, WA-8, WE-14
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1113
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD20
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P11836
Gene Symbols: Ms4a1
Immunogen: A peptide corresponding to the C-terminus of human CD20.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: RM272
Conjugate: Unconjugated
Gene: Ms4a1
Gene Alias: AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 931
Content And Storage: -20°C
Form: Liquid
Antigen:
CD20
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P11836
Gene Symbols:
Ms4a1
Immunogen:
A peptide corresponding to the C-terminus of human CD20.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
RM272
Conjugate:
Unconjugated
Gene:
Ms4a1
Gene Alias:
AA960661, APY, ATOPY, B1, B-cell differentiation antigen Ly-44, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35, Cd20, CD20 antigen, CD20 cell surface protein, CD20 receptor, CVID5, EGK_06167, Fc epsilon receptor I beta chain, Fc Fragment of IgE high affinity I receptor for beta polypeptide, FCER1B, High affinity immunoglobulin epsilon receptor subunit beta, IgE Fc receptor subunit beta, IGEL, IGER, IGHER, LEU16, LEU-16, Leukocyte surface antigen Leu-16, Ly44, Ly-44, Lymphocyte antigen 44, membrane spanning 4-domains A1, membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, membrane-spanning 4-domains, subfamily A, member 2, MGC3969, MS4A1, MS4A2, S7
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
931
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD56 (NCAM)
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P13591, P13595
Gene Symbols: Ncam1
Immunogen: A peptide corresponding to the C-terminus of human CD56.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM315
Conjugate: Unconjugated
Gene: Ncam1
Gene Alias: adhesion molecule, antigen recognized by monoclonal antibody 5.1H11, Cd56, CD-56, CD56 120 kDa GPI-linked isoform, CD56 140 kDa isoform, CD56 140 kDa VASE isoform, E NCAM, E-NCAM, MSK39, N CAM1, NCAM, N-CAM, Ncam1, N-CAM-1, NCAM-1, NCAMC, NCAM-C, neural cell adhesion molecule, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM, sCD56, sNCAM, soluble CD56, soluble NCAM
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 17967, 4684
Content And Storage: -20°C
Form: Liquid
Antigen:
CD56 (NCAM)
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P13591, P13595
Gene Symbols:
Ncam1
Immunogen:
A peptide corresponding to the C-terminus of human CD56.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM315
Conjugate:
Unconjugated
Gene:
Ncam1
Gene Alias:
adhesion molecule, antigen recognized by monoclonal antibody 5.1H11, Cd56, CD-56, CD56 120 kDa GPI-linked isoform, CD56 140 kDa isoform, CD56 140 kDa VASE isoform, E NCAM, E-NCAM, MSK39, N CAM1, NCAM, N-CAM, Ncam1, N-CAM-1, NCAM-1, NCAMC, NCAM-C, neural cell adhesion molecule, Neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM, sCD56, sNCAM, soluble CD56, soluble NCAM
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
17967, 4684
Content And Storage:
-20°C
Form:
Liquid