PIMA533069
AKT1 (E17K Mutant) Recombinant Rabbit Monoclonal Antibody (RM336), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533069-Each-of-1 | In Stock | ₹ 48,555.30 |
PIMA533069 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,555.30
GST (18%): ₹ 8,739.954
Total Price: ₹ 57,295.254
Antigen
AKT1 (E17K Mutant)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P31749
Gene Symbols
AKT1
Immunogen
A peptide corresponding to Akt E17K mutant.
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
RM336
Conjugate
Unconjugated
Gene
AKT1
Gene Alias
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
207
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to Akt E17K mutant
- No cross reactivity with wild type Akt
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts
- AKT1 and the related AKT2 are activated by platelet-derived growth factor
- The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1
- It was shown that the activation occurs through phosphatidylinositol 3-kinase
- In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival
- Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery
- Mutations in this gene have been associated with the Proteus syndrome
- Multiple alternatively spliced transcript variants have been found for this gene.
Compare Similar Items
Show Difference
Antigen: AKT1 (E17K Mutant)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P31749
Gene Symbols: AKT1
Immunogen: A peptide corresponding to Akt E17K mutant.
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: RM336
Conjugate: Unconjugated
Gene: AKT1
Gene Alias: AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 207
Content And Storage: -20°C
Form: Liquid
Antigen:
AKT1 (E17K Mutant)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P31749
Gene Symbols:
AKT1
Immunogen:
A peptide corresponding to Akt E17K mutant.
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
RM336
Conjugate:
Unconjugated
Gene:
AKT1
Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
207
Content And Storage:
-20°C
Form:
Liquid
Antigen: AKT1 (PH domain)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P31749
Gene Symbols: AKT1
Immunogen: A peptide corresponding to the PH domain of human AKT.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM316
Conjugate: Unconjugated
Gene: AKT1
Gene Alias: AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 207
Content And Storage: -20°C
Form: Liquid
Antigen:
AKT1 (PH domain)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P31749
Gene Symbols:
AKT1
Immunogen:
A peptide corresponding to the PH domain of human AKT.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM316
Conjugate:
Unconjugated
Gene:
AKT1
Gene Alias:
AKT, AKT serine/threonine kinase 1, AKT1, AKT1m, CWS6, PKB, PKB alpha, PKB-ALPHA, PRKBA, Protein kinase B, Protein kinase B alpha, proto-oncogene c-Akt, RAC, rac protein kinase alpha, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, RAC-PK-alpha, serine-threonine protein kinase, v-akt murine thymoma viral oncogene homolog 1, v-akt murine thymoma viral oncogene-like protein 1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
207
Content And Storage:
-20°C
Form:
Liquid
Antigen: MMP12
Classification: Recombinant Monoclonal
Concentration: 0.05 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P39900
Gene Symbols: Mmp12
Immunogen: A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM381
Conjugate: Unconjugated
Gene: Mmp12
Gene Alias: 3.4.24.65, AV378681, HME, Macrophage elastase, macrophage metalloelastase, macrophage-metalloelastase, matrix metallo protease, matrix metallopeptidase 12, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12, matrix metalloproteinase 12 (macrophage elastase), matrix metalloproteinase-12, ME, MGC138506, MME, Mmel, MMP, Mmp12, MMP-12, MMPs
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4321
Content And Storage: -20°C
Form: Liquid
Antigen:
MMP12
Classification:
Recombinant Monoclonal
Concentration:
0.05 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P39900
Gene Symbols:
Mmp12
Immunogen:
A peptide corresponding to the C-terminus of human Matrix metalloproteinase-12 (MMP-12).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM381
Conjugate:
Unconjugated
Gene:
Mmp12
Gene Alias:
3.4.24.65, AV378681, HME, Macrophage elastase, macrophage metalloelastase, macrophage-metalloelastase, matrix metallo protease, matrix metallopeptidase 12, matrix metallopeptidase 12 (macrophage elastase), matrix metalloproteinase 12, matrix metalloproteinase 12 (macrophage elastase), matrix metalloproteinase-12, ME, MGC138506, MME, Mmel, MMP, Mmp12, MMP-12, MMPs
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4321
Content And Storage:
-20°C
Form:
Liquid
Antigen: Nkx2.1
Classification: Recombinant Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P43699
Gene Symbols: NKX2-1
Immunogen: A peptide corresponding to the N-terminus of human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM373
Conjugate: Unconjugated
Gene: NKX2-1
Gene Alias: AV026640, BCH, BHC, homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NK-2, NK2 homeobox 1, NK-2 homolog A, NKX2.1, Nkx-2.1, NKX2-1, NKX2A, NMTC1, RNA polymerase I transcription termination factor, T/EBP, TEBP, Thyroid nuclear factor 1, thyroid transcription factor 1, thyroid transcription factor 1 TTF-1 NK-2, thyroid transcription factor 1-like, thyroid-specific enhancer-binding protein, tinman, TITF1, TTF1, TTF-1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 7080
Content And Storage: -20°C
Form: Liquid
Antigen:
Nkx2.1
Classification:
Recombinant Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P43699
Gene Symbols:
NKX2-1
Immunogen:
A peptide corresponding to the N-terminus of human TTF1 (Thyroid transcription factor 1) (Homeobox protein Nkx-2.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM373
Conjugate:
Unconjugated
Gene:
NKX2-1
Gene Alias:
AV026640, BCH, BHC, homeobox protein NK-2 homolog A, Homeobox protein Nkx-2.1, NK-2, NK2 homeobox 1, NK-2 homolog A, NKX2.1, Nkx-2.1, NKX2-1, NKX2A, NMTC1, RNA polymerase I transcription termination factor, T/EBP, TEBP, Thyroid nuclear factor 1, thyroid transcription factor 1, thyroid transcription factor 1 TTF-1 NK-2, thyroid transcription factor 1-like, thyroid-specific enhancer-binding protein, tinman, TITF1, TTF1, TTF-1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
7080
Content And Storage:
-20°C
Form:
Liquid