PIMA533089

Phospho-p38 MAPK beta (Thr180, Tyr182) Recombinant Rabbit Monoclonal Antibody (RM243), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA533089-Each-of-1 In Stock ₹ 46,501.86

PIMA533089 - Each of 1

₹ 46,501.86

In Stock

Quantity

1

Base Price: ₹ 46,501.86

GST (18%): ₹ 8,370.335

Total Price: ₹ 54,872.195

Antigen

Phospho-p38 MAPK beta (Thr180, Tyr182)

Classification

Recombinant Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

Q15759

Gene Symbols

MAPK11

Immunogen

A phospho-peptide corresponding to human Phosphop38 MAPK (Thr180/Tyr182).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM243

Conjugate

Unconjugated

Gene

MAPK11

Gene Alias

MAP kinase 11, MAP kinase p38 beta, MAPK 11, Mapk11, mitogen activated protein kinase 11, mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, mitogen-activated protein kinase p38-2, OTTHUMP00000196655, p38-2, P38b, p38beta, P38BETA2, Prkm11, protein kinase, mitogen activated kinase, 11, p38beta, SAPK2, SAPK2b, Stress-activated protein kinase 2b, stress-activated protein kinase-2, stress-activated protein kinase-2b

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

5600

Content And Storage

-20°C

Form

Liquid

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Description

  • Specificity: reacts to p38 MAPK only when dual phosphorylation at Thr180 and Tyr182 is observed
  • There is no cross-reactivity with p38 MAPK without dual phosphorylation at Thr180 and Tyr182
  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • MAPK11 (p38 beta) is a serine/threonine kinase which is involved in a variety of cellular processes, and is activated by proinflammatory cytokines and environmental stress
  • Mitogen-activated protein kinase 11
  • The protein encoded by p38 MAPK beta is a member of the MAP kinase family
  • MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development
  • This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress
  • This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6
  • Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA533089

--


Antigen:
Phospho-p38 MAPK beta (Thr180, Tyr182)

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q15759

Gene Symbols:
MAPK11

Immunogen:
A phospho-peptide corresponding to human Phosphop38 MAPK (Thr180/Tyr182).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM243

Conjugate:
Unconjugated

Gene:
MAPK11

Gene Alias:
MAP kinase 11, MAP kinase p38 beta, MAPK 11, Mapk11, mitogen activated protein kinase 11, mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, mitogen-activated protein kinase p38-2, OTTHUMP00000196655, p38-2, P38b, p38beta, P38BETA2, Prkm11, protein kinase, mitogen activated kinase, 11, p38beta, SAPK2, SAPK2b, Stress-activated protein kinase 2b, stress-activated protein kinase-2, stress-activated protein kinase-2b

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
5600

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533091

--


Antigen:
CD163

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q86VB7

Gene Symbols:
CD163

Immunogen:
A peptide corresponding to the N-terminus of human CD163.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM371

Conjugate:
Unconjugated

Gene:
CD163

Gene Alias:
CD163, CD163 antigen, CD163 molecule, CD163v2, CD163v3, Hemoglobin scavenger receptor, M130, macrophage-associated antigen, MM130, putative CD163 antigen, SCARI1, Scavenger receptor cysteine-rich type 1 protein M130, sCD163, Soluble CD163, Soluble sCD163

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9332

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533093

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Antigen:
ALK

Classification:
Recombinant Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q9UM73

Gene Symbols:
ALK

Immunogen:
A peptide corresponding to the C-terminus of human ALK (Anaplastic lymphoma kinase).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
RM361

Conjugate:
Unconjugated

Gene:
ALK

Gene Alias:
Alk, ALK tyrosine kinase receptor, ALK/NPM1 fusion gene, anaplastic lymphoma kinase, Anaplastic lymphoma kinase Ki1, Anaplastic Lymphoma Kinase p80, anaplastic lymphoma receptor tyrosine kinase, CD246, CD246 antigen, EC 2.7.10.1, kinase ALK, mutant anaplastic lymphoma kinase, NBLST3, npm-alk, p80, Tcrz, TFG/ALK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
238

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA533094

--


Antigen:
SATB2

Classification:
Recombinant Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
Q9UPW6

Gene Symbols:
SATB2

Immunogen:
A peptide corresponding to the C-terminus of human DNA-binding protein SATB2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM365

Conjugate:
Unconjugated

Gene:
SATB2

Gene Alias:
DNA-binding protein SATB2, FLJ21474, FLJ32076, GLSS, KIAA1034, KIAA1034-like DNA binding protein, MGC119474, MGC119477, mKIAA1034, RGD1562369, SATB family member 2, SATB homeobox 2, SATB2, special AT-rich sequence binding protein 2, special AT-rich sequence-binding protein 2, two cut domains-containing homeodomain protein

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23314

Content And Storage:
-20°C

Form:
Liquid