PIMA533039
Estrogen Receptor alpha Recombinant Rabbit Monoclonal Antibody (RM292), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533039-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA533039 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Estrogen Receptor alpha
Classification
Recombinant Monoclonal
Concentration
0.05 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P03372
Gene Symbols
ESR1
Immunogen
A peptide corresponding to residues near the Nterminus of human ER-alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
RM292
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 grou
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2099
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to human ER-alpha (Estrogen receptor)
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
Compare Similar Items
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Antigen: Estrogen Receptor alpha
Classification: Recombinant Monoclonal
Concentration: 0.05 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P03372
Gene Symbols: ESR1
Immunogen: A peptide corresponding to residues near the Nterminus of human ER-alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM292
Conjugate: Unconjugated
Gene: ESR1
Gene Alias: DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 grou
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2099
Content And Storage: -20°C
Form: Liquid
Antigen:
Estrogen Receptor alpha
Classification:
Recombinant Monoclonal
Concentration:
0.05 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
A peptide corresponding to residues near the Nterminus of human ER-alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM292
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 grou
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD61 (Integrin beta 3)
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P05106
Gene Symbols: ITGB3
Immunogen: A peptide corresponding to the internal region of human Integrin beta3.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM382
Conjugate: Unconjugated
Gene: ITGB3
Gene Alias: antigen CD61, BDPLT16, BDPLT2, beta3 integrin, CD61, EGK_08849, glycoprotein GPIIIa, glycoprotein IIIa, GP3A, GPIIIa, GT, INGRB3, integrin beta 3, integrin beta 3 (Cd61), integrin beta-3, integrin beta-3 subunit, integrin subunit beta 3, integrin, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGB3, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet gpIIIa, platelet membrane glycoprotein IIIa
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3690
Content And Storage: -20°C
Form: Liquid
Antigen:
CD61 (Integrin beta 3)
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P05106
Gene Symbols:
ITGB3
Immunogen:
A peptide corresponding to the internal region of human Integrin beta3.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM382
Conjugate:
Unconjugated
Gene:
ITGB3
Gene Alias:
antigen CD61, BDPLT16, BDPLT2, beta3 integrin, CD61, EGK_08849, glycoprotein GPIIIa, glycoprotein IIIa, GP3A, GPIIIa, GT, INGRB3, integrin beta 3, integrin beta 3 (Cd61), integrin beta-3, integrin beta-3 subunit, integrin subunit beta 3, integrin, beta 3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITGB3, platelet glycoprotein IIIa, platelet glycoprotein IIIa integrin subunit beta 3, platelet gpIIIa, platelet membrane glycoprotein IIIa
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3690
Content And Storage:
-20°C
Form:
Liquid
Antigen: Placental Alkaline Phosphatase
Classification: Recombinant Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P05187
Gene Symbols: ALPP
Immunogen: A peptide corresponding to the N-terminus of human PLAP (Placental alkaline phosphatase).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM317
Conjugate: Unconjugated
Gene: ALPP
Gene Alias: Alkaline phosphatase placental type, Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, Alp1, ALPP, AP-TNAP, DOA1, FLJ11281, FLJ40094, FLJ61142, FLJ93059, Germ-cell alkaline phosphatase, glycerophosphatase, HOPS, MGC161443, MGC167935, nagao Isozyme, P PLAP, PALP, PLA2P, PLAA, placental alkaline phosphatase 1, placental heat-stable alkaline phosphatase, PLAP, PLAP1, PLAP-1, rCG23846-like, Regan isozyme, TNAP, TNSALP
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 250
Content And Storage: -20°C
Form: Liquid
Antigen:
Placental Alkaline Phosphatase
Classification:
Recombinant Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P05187
Gene Symbols:
ALPP
Immunogen:
A peptide corresponding to the N-terminus of human PLAP (Placental alkaline phosphatase).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM317
Conjugate:
Unconjugated
Gene:
ALPP
Gene Alias:
Alkaline phosphatase placental type, Alkaline phosphatase Regan isozyme, alkaline phosphatase, placental, alkaline phosphatase, placental type, alkaline phosphomonoesterase, ALP, Alp1, ALPP, AP-TNAP, DOA1, FLJ11281, FLJ40094, FLJ61142, FLJ93059, Germ-cell alkaline phosphatase, glycerophosphatase, HOPS, MGC161443, MGC167935, nagao Isozyme, P PLAP, PALP, PLA2P, PLAA, placental alkaline phosphatase 1, placental heat-stable alkaline phosphatase, PLAP, PLAP1, PLAP-1, rCG23846-like, Regan isozyme, TNAP, TNSALP
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
250
Content And Storage:
-20°C
Form:
Liquid
Antigen: Cytokeratin 5/6
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P02538, P13647
Gene Symbols: KRT5, KRT6A
Immunogen: A peptide corresponding to the C-terminus of Human Cytokeratin 5.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM341
Conjugate: Unconjugated
Gene: KRT5
Gene Alias: 2310016L08Rik, 3300001P10Rik, 58 kDa cytokeratin, 60-kDa keratin, AW146334, CK5, CK-5, CK6A, CK-6A, CK6C, CK-6C, CK6D, CK-6D, CK-6E, cytokeratin 5, cytokeratin 6A, cytokeratin 6C, cytokeratin 6D, cytokeratin-5, Cytokeratin-6A, cytokeratin-6C, Cytokeratin-6D, cytokeratin-6E, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, Hom s 5, K5, K6A, K6a keratin, K6C, K6D, kamp-keratin derived antimicrobial peptide, KDAMP, Ker2, keratin 5, keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5, type II, keratin 6A, keratin 6A, , type II, keratin 6A, type II, keratin complex 2, basic, gene 5, keratin complex 2, basic, gene 6a, keratin complex 2, basic, gene 6c, keratin complex 2, gene 6a, keratin K6, keratin K6h, keratin, epidermal type II, K6A, keratin, type II cytoskeletal 5, Keratin, type II cytoskeletal 6A, keratin, type II cytoskeletal 6C, keratin-5, keratin-6A, Keratin-6-alpha, keratin-6C, Krt2-5, Krt2-6, Krt2-6a, Krt2-6c, krt5, KRT5A, Krt6, Krt6a, KRT6C, KRT6D, LOC683313, mK6[a], MK6a, mK6-alpha, PC3, Sak57, similar to keratin complex 2, basic, gene 6a, Tfip8, tuftelin interacting protein 8, type-II keratin Kb12, type-II keratin Kb5, Type-II keratin Kb6
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3852, 3853
Content And Storage: -20°C
Form: Liquid
Antigen:
Cytokeratin 5/6
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P02538, P13647
Gene Symbols:
KRT5, KRT6A
Immunogen:
A peptide corresponding to the C-terminus of Human Cytokeratin 5.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM341
Conjugate:
Unconjugated
Gene:
KRT5
Gene Alias:
2310016L08Rik, 3300001P10Rik, 58 kDa cytokeratin, 60-kDa keratin, AW146334, CK5, CK-5, CK6A, CK-6A, CK6C, CK-6C, CK6D, CK-6D, CK-6E, cytokeratin 5, cytokeratin 6A, cytokeratin 6C, cytokeratin 6D, cytokeratin-5, Cytokeratin-6A, cytokeratin-6C, Cytokeratin-6D, cytokeratin-6E, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, Hom s 5, K5, K6A, K6a keratin, K6C, K6D, kamp-keratin derived antimicrobial peptide, KDAMP, Ker2, keratin 5, keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5, type II, keratin 6A, keratin 6A, , type II, keratin 6A, type II, keratin complex 2, basic, gene 5, keratin complex 2, basic, gene 6a, keratin complex 2, basic, gene 6c, keratin complex 2, gene 6a, keratin K6, keratin K6h, keratin, epidermal type II, K6A, keratin, type II cytoskeletal 5, Keratin, type II cytoskeletal 6A, keratin, type II cytoskeletal 6C, keratin-5, keratin-6A, Keratin-6-alpha, keratin-6C, Krt2-5, Krt2-6, Krt2-6a, Krt2-6c, krt5, KRT5A, Krt6, Krt6a, KRT6C, KRT6D, LOC683313, mK6[a], MK6a, mK6-alpha, PC3, Sak57, similar to keratin complex 2, basic, gene 6a, Tfip8, tuftelin interacting protein 8, type-II keratin Kb12, type-II keratin Kb5, Type-II keratin Kb6
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3852, 3853
Content And Storage:
-20°C
Form:
Liquid