PIMA532205
Phospho-Estrogen Receptor alpha (Ser118) Recombinant Rabbit Monoclonal Antibody (SC05-87), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532205-Each-of-1 | In Stock | ₹ 45,646.26 |
PIMA532205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,646.26
GST (18%): ₹ 8,216.327
Total Price: ₹ 53,862.587
Antigen
Phospho-Estrogen Receptor alpha (Ser118)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
P03372
Gene Symbols
ESR1
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser118 of Human ESR1 aa 110-154
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
SC05-87
Conjugate
Unconjugated
Gene
ESR1
Gene Alias
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
2099
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
- The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
- When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
- There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
- Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
- Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
- They also play a role in other tissues such as bone
- Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.
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Antigen: Phospho-Estrogen Receptor alpha (Ser118)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P03372
Gene Symbols: ESR1
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser118 of Human ESR1 aa 110-154
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC05-87
Conjugate: Unconjugated
Gene: ESR1
Gene Alias: DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 2099
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-Estrogen Receptor alpha (Ser118)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P03372
Gene Symbols:
ESR1
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser118 of Human ESR1 aa 110-154
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC05-87
Conjugate:
Unconjugated
Gene:
ESR1
Gene Alias:
DKFZp686N23123, ER, Er alpha, ER36, ERa, ERalpha, ER-alpha, ERalpha protein, ESR, esr 1, Esr1, esr-1, ESRA, Estr, Estra, Estradiol receptor, estrogen nuclear receptor alpha, Estrogen receptor, estrogen receptor 1, estrogen receptor 1 (alpha), estrogen receptor alpha, estrogen receptor alpha c-terminus splice variant 1-2, estrogen receptor alpha E1-E2-1-2, estrogen receptor alpha E1-N2-E2-1-2, estrogen receptor alpha splice variant, CTERP-1, estrogen receptor alpha splice variant, ERalphaDup5, estrogen receptor alpha splice variant, ERalphai45a, estrogen receptor alpha splice variant, ERalphai45bL, estrogen receptor alpha splice variant, ERalphai45bS, estrogen receptor alpha splice variant, ERalphai45c, estrogen receptor alpha splice variant, ERalphai56, estrogen receptor alpha splice variant, ERalphai67, estrogen receptor alpha variant delta 4, estrogen receptor protein, estrogen receptor, alpha, ESTRR, hER-alpha36, I79_001166, Nr3a1, nuclear receptor, nuclear receptor subfamily 3 group A member 1, RNESTROR, RP1-130E4.1, unnamed protein product
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
2099
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ISL1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P61371, P61372
Gene Symbols: ISL1
Immunogen: Synthetic peptide within Human Islet 1 aa 262-205
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot, Western Blot
Clone: SC05-64
Conjugate: Unconjugated
Gene: ISL1
Gene Alias: Insulin gene enhancer protein ISL-1, insulin related protein, ISL LIM homeobox 1, Isl1, Isl-1, isl-1 homeobox, ISL1 transcription factor LIM/homeodomain (islet-1), ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain 1, isl-1=homeobox, Islet 1, ISLET1, islet-1, Lim-homeodomain protein Islet1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16392, 3670
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ISL1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P61371, P61372
Gene Symbols:
ISL1
Immunogen:
Synthetic peptide within Human Islet 1 aa 262-205
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot, Western Blot
Clone:
SC05-64
Conjugate:
Unconjugated
Gene:
ISL1
Gene Alias:
Insulin gene enhancer protein ISL-1, insulin related protein, ISL LIM homeobox 1, Isl1, Isl-1, isl-1 homeobox, ISL1 transcription factor LIM/homeodomain (islet-1), ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain 1, isl-1=homeobox, Islet 1, ISLET1, islet-1, Lim-homeodomain protein Islet1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16392, 3670
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-TrkB (Tyr817)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P15209, Q16620, Q63604
Gene Symbols: Ntrk2
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr817 of Human TrkB aa 789-822
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: SC0556
Conjugate: Unconjugated
Gene: Ntrk2
Gene Alias: AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 18212, 25054, 4915
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-TrkB (Tyr817)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P15209, Q16620, Q63604
Gene Symbols:
Ntrk2
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Tyr817 of Human TrkB aa 789-822
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
SC0556
Conjugate:
Unconjugated
Gene:
Ntrk2
Gene Alias:
AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
18212, 25054, 4915
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: PIK3CB
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P42338
Gene Symbols: PIK3CB
Immunogen: Synthetic peptide within Human PIK3CB aa 5-52
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Western Blot
Clone: SC0580
Conjugate: Unconjugated
Gene: PIK3CB
Gene Alias: 1110001J02Rik, AI447572, catalytic phosphatidylinositol 3-kinase beta, p110beta, phosphatidylinositol 3-kinase catalytic subunit beta isoform, phosphatidylinositol 3-kinase, catalytic subunit, beta isoform, phosphatidylinositol 3-kinase, catalytic, beta polypeptide, phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta, phosphoinositide-3-kinase, catalytic, beta polypeptide, PI3K, PI3Kbeta, PI3K-beta, pi3kcb, PI3-kinase p110 subunit beta, PI3-kinase subunit beta, PIK3C1, Pik3cb, PtdIns-3-kinase p110, ptdIns-3-kinase subunit beta, ptdIns-3-kinase subunit p110-beta
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 5291
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
PIK3CB
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P42338
Gene Symbols:
PIK3CB
Immunogen:
Synthetic peptide within Human PIK3CB aa 5-52
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Western Blot
Clone:
SC0580
Conjugate:
Unconjugated
Gene:
PIK3CB
Gene Alias:
1110001J02Rik, AI447572, catalytic phosphatidylinositol 3-kinase beta, p110beta, phosphatidylinositol 3-kinase catalytic subunit beta isoform, phosphatidylinositol 3-kinase, catalytic subunit, beta isoform, phosphatidylinositol 3-kinase, catalytic, beta polypeptide, phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta, phosphoinositide-3-kinase, catalytic, beta polypeptide, PI3K, PI3Kbeta, PI3K-beta, pi3kcb, PI3-kinase p110 subunit beta, PI3-kinase subunit beta, PIK3C1, Pik3cb, PtdIns-3-kinase p110, ptdIns-3-kinase subunit beta, ptdIns-3-kinase subunit p110-beta
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
5291
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid