PIMA532289

ATG5 Recombinant Rabbit Monoclonal Antibody (SN73-07), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532289-Each-of-1 In Stock ₹ 46,929.66

PIMA532289 - Each of 1

₹ 46,929.66

In Stock

Quantity

1

Base Price: ₹ 46,929.66

GST (18%): ₹ 8,447.339

Total Price: ₹ 55,376.999

Antigen

ATG5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

Q3MQ06, Q99J83, Q9H1Y0

Gene Symbols

Atg5

Immunogen

Synthetic peptide within Human ATG5 aa 1-50

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SN73-07

Conjugate

Unconjugated

Gene

Atg5

Gene Alias

2010107M05Rik, 3110067M24Rik, APG 5, APG5, APG5 autophagy 5 like (APG5L), APG5 autophagy 5-like protein, APG5 autophagy 5-like protein, isoform 1, APG5L, APG5-LIKE, apoptosis-specific protein, Apoptosis-specific protein (ASP), ASP, atg5, Atg-5, ATG5 autophagy related 5 homolog, ATG5 autophagy related 5 homolog (S. cerevisiae), atg5.L, Atg5l, Atg5-PA, autophagy 5-like protein, autophagy protein 5, autophagy related 5, autophagy related 5 L homeolog, autophagy related 5-like protein, Autophagy-related 5, autophagy-specific gene 5, AW319544, C88337, CG1643, CG1643-PA, DmAtg5, Dmel\CG1643, Dmel_CG1643, hAPG5, hypothetical protein LOC532686, LD34980p, Paddy, XELAEV_18027227mg, zgc:100934

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

11793, 365601, 9474

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • ATG5 (Autophagy Related 5) is an important element for autophagy and may play an important role in the apoptotic process
  • ATG5 is also involved in other cellular processes that include mitochondrial quality control after oxidative damage, negative regulation of the innate anti-viral immune response, lymphocyte development and proliferation, MHC II antigen presentation, and adipocyte differentiation
  • Following conjugation to ATG12, the conjugate participates in the formation of autophagosome
  • ATG5 contributes to autophagic cell death by interacting with Fas-associated protein with death domain (FADD)
  • The ATG5-ATG12 conjugate forms a cup-shaped isolation membrane that then detaches from the membrane immediately before or after autophagosome formation is completed
  • APG5 may play a role in the apoptotic process, possibly within the modified cytoskeleton
  • Further, APG5 expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity
  • The APG5-APG12 conjugate also associates with innate immune response proteins such as RIG-I and VISA (also known as IPS-1), inhibiting type I interferon production and permitting viral replication in host cells
  • Diseases associated with ATG5 dysfunction include spinocerebellar ataxia.

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Img

Thermo Scientific

PIMA532289

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Antigen:
ATG5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q3MQ06, Q99J83, Q9H1Y0

Gene Symbols:
Atg5

Immunogen:
Synthetic peptide within Human ATG5 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN73-07

Conjugate:
Unconjugated

Gene:
Atg5

Gene Alias:
2010107M05Rik, 3110067M24Rik, APG 5, APG5, APG5 autophagy 5 like (APG5L), APG5 autophagy 5-like protein, APG5 autophagy 5-like protein, isoform 1, APG5L, APG5-LIKE, apoptosis-specific protein, Apoptosis-specific protein (ASP), ASP, atg5, Atg-5, ATG5 autophagy related 5 homolog, ATG5 autophagy related 5 homolog (S. cerevisiae), atg5.L, Atg5l, Atg5-PA, autophagy 5-like protein, autophagy protein 5, autophagy related 5, autophagy related 5 L homeolog, autophagy related 5-like protein, Autophagy-related 5, autophagy-specific gene 5, AW319544, C88337, CG1643, CG1643-PA, DmAtg5, Dmel\CG1643, Dmel_CG1643, hAPG5, hypothetical protein LOC532686, LD34980p, Paddy, XELAEV_18027227mg, zgc:100934

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11793, 365601, 9474

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532290

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Antigen:
NSD3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q6P2L6, Q9BZ95

Gene Symbols:
Nsd3

Immunogen:
Synthetic peptide within Human NSD3 aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot

Clone:
SN07-11

Conjugate:
Unconjugated

Gene:
Nsd3

Gene Alias:
6720429E03, A530023P05, AI528490, DC28, DKFZp667H044, FLJ20353, Histone-lysine N-methyltransferase NSD3, MGC126766, MGC142029, NSD3, nuclear receptor binding SET domain protein 3, nuclear SET domain-containing protein 3, pp14328, Protein whistle, WHISTLE, WHSC1L1, WHSC1-like 1 isoform 9 with methyltransferase activity to lysine, WHSC1-like protein 1, Wolf-Hirschhorn syndrome candidate 1-like 1, Wolf-Hirschhorn syndrome candidate 1-like 1 (human), Wolf-Hirschhorn syndrome candidate 1-like protein 1, Wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
234135, 290831, 54904

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532292

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Antigen:
TNFAIP3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P21580, Q60769

Gene Symbols:
TNFAIP3

Immunogen:
Synthetic peptide within Human TNFAIP3 aa 491-540

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SN07-31

Conjugate:
Unconjugated

Gene:
TNFAIP3

Gene Alias:
A20, A20p37, A20p50, AISBL, OTU domain-containing protein 7C, OTUD7C, Putative DNA-binding protein A20, RP11-356I2.3, TNF alpha induced protein 3, TNF alpha-induced protein 3, TNFA1P2, TNFAIP3, TNFAIP3 (A20), Tnfip3, Tumor necrosis factor alpha-induced protein 3, tumor necrosis factor induced protein 3, tumor necrosis factor inducible protein A20, tumor necrosis factor, alpha induced protein 3, tumor necrosis factor, alpha-induced protein 3, zinc finger protein A20

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
21929, 7128

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532293

--


Antigen:
AGTR2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P35351, P35374, P50052

Gene Symbols:
Agtr2

Immunogen:
Synthetic peptide within Human Angiotensin II Type 2 Receptoraa 311-363

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
SN71-03

Conjugate:
Unconjugated

Gene:
Agtr2

Gene Alias:
AGTR2, AI316812, Angiotensin ii at2, angiotensin II receptor type 2, angiotensin II receptor, type 2, angiotensin II type 2 receptor, angiotensin II type-2 receptor, angiotensin receptor 2, AT<sub>2</sub>R, AT2, AT2 receptor, AT2R, AT2-R, ATGR2, AW107640, MRX88, type-2 angiotensin II receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11609, 186, 24182

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid