PIMA532751
Phospho-ATM (Ser1981) Recombinant Rabbit Monoclonal Antibody (JM93-25), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA532751-Each-of-1 | In Stock | ₹ 45,988.50 |
PIMA532751 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,988.50
GST (18%): ₹ 8,277.93
Total Price: ₹ 54,266.43
Antigen
Phospho-ATM (Ser1981)
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.
Q13315, Q62388
Gene Symbols
ATM
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser1981 of Human ATM aa 1940-1989
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone
JM93-25
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
11920, 472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
Compare Similar Items
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Antigen: Phospho-ATM (Ser1981)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q13315, Q62388
Gene Symbols: ATM
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser1981 of Human ATM aa 1940-1989
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JM93-25
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11920, 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-ATM (Ser1981)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q13315, Q62388
Gene Symbols:
ATM
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser1981 of Human ATM aa 1940-1989
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JM93-25
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11920, 472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Phospho-MLKL (Ser345)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: Q9D2Y4
Gene Symbols: Mlkl
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser345 of mouse MLKL aa 314-363
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry
Clone: JM92-37
Conjugate: Unconjugated
Gene: Mlkl
Gene Alias: 9130019I15Rik, hMLKL, mixed lineage kinase domain like pseudokinase, mixed lineage kinase domain-like, mixed lineage kinase domain-like protein, Mlkl, rCG51567-like
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 74568
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Phospho-MLKL (Ser345)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
Q9D2Y4
Gene Symbols:
Mlkl
Immunogen:
Synthetic phospho-peptide corresponding to residues surrounding Ser345 of mouse MLKL aa 314-363
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry
Clone:
JM92-37
Conjugate:
Unconjugated
Gene:
Mlkl
Gene Alias:
9130019I15Rik, hMLKL, mixed lineage kinase domain like pseudokinase, mixed lineage kinase domain-like, mixed lineage kinase domain-like protein, Mlkl, rCG51567-like
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
74568
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: CD66e (CEA)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P06731
Gene Symbols: Ceacam5
Immunogen: Human Carcinoembryonic Antigen (CEA) purified from human liver.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone: JM93-28
Conjugate: Unconjugated
Gene: Ceacam5
Gene Alias: 1600029H12Rik, Carcinoembryonic antigen, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CEA, CEACAM5, Meconium antigen 100, OTTHUMP00000199033, pregnancy-specific glycoprotein 30, Psg30, sCD66e, soluble CD66e
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1048
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD66e (CEA)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P06731
Gene Symbols:
Ceacam5
Immunogen:
Human Carcinoembryonic Antigen (CEA) purified from human liver.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Clone:
JM93-28
Conjugate:
Unconjugated
Gene:
Ceacam5
Gene Alias:
1600029H12Rik, Carcinoembryonic antigen, carcinoembryonic antigen related cell adhesion molecule 5, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e, CEA, CEACAM5, Meconium antigen 100, OTTHUMP00000199033, pregnancy-specific glycoprotein 30, Psg30, sCD66e, soluble CD66e
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1048
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: ENO1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.: P04764, P06733, P17182
Gene Symbols: ENO1
Immunogen: Synthetic peptide within Human ENO1 aa 1-50
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat, Zebrafish
Product Type: Antibody
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone: JM63-53
Conjugate: Unconjugated
Gene: ENO1
Gene Alias: 0610008I15, 2-phospho-D-glycerate hydrolase, 2-phospho-D-glycerate hydro-lyase, AL022784, alpha enolase, alpha enolase like 1, alpha-enolase, alpha-enolase, c-myc promoter-binding protein-1, c-Myc promoter binding protein, C-myc promoter-binding protein, Eno1, Eno-1, ENO1L1, enoa, Enolase 1, enolase 1, (alpha), enolase 1, alpha non-neuron, enolase-alpha, epididymis secretory protein Li 17, HEL-S-17, MBP-1, MBPB1, MPB1, MPB-1, MYC promoter-binding protein 1, NNE, Non-neural enolase, phosphopyruvate hydratase, Plasminogen-binding protein, PPH, tau-crystallin
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 13806, 2023, 24333
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
ENO1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P04764, P06733, P17182
Gene Symbols:
ENO1
Immunogen:
Synthetic peptide within Human ENO1 aa 1-50
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat, Zebrafish
Product Type:
Antibody
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot, Western Blot
Clone:
JM63-53
Conjugate:
Unconjugated
Gene:
ENO1
Gene Alias:
0610008I15, 2-phospho-D-glycerate hydrolase, 2-phospho-D-glycerate hydro-lyase, AL022784, alpha enolase, alpha enolase like 1, alpha-enolase, alpha-enolase, c-myc promoter-binding protein-1, c-Myc promoter binding protein, C-myc promoter-binding protein, Eno1, Eno-1, ENO1L1, enoa, Enolase 1, enolase 1, (alpha), enolase 1, alpha non-neuron, enolase-alpha, epididymis secretory protein Li 17, HEL-S-17, MBP-1, MBPB1, MPB1, MPB-1, MYC promoter-binding protein 1, NNE, Non-neural enolase, phosphopyruvate hydratase, Plasminogen-binding protein, PPH, tau-crystallin
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
13806, 2023, 24333
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid