PIMA533213
ATM Recombinant Rabbit Monoclonal Antibody (4E11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533213-Each-of-1 | In Stock | ₹ 48,555.30 |
PIMA533213 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,555.30
GST (18%): ₹ 8,739.954
Total Price: ₹ 57,295.254
Antigen
ATM
Classification
Recombinant Monoclonal
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q13315, Q62388
Gene Symbols
ATM
Immunogen
A synthesized peptide derived from human ATM
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
4E11
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
11920, 472
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Related Products
Description
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q13315, Q62388
Gene Symbols: ATM
Immunogen: A synthesized peptide derived from human ATM
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 4E11
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11920, 472
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
ATM
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q13315, Q62388
Gene Symbols:
ATM
Immunogen:
A synthesized peptide derived from human ATM
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
4E11
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11920, 472
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-RSK1 (Thr359, Ser363)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q15418
Gene Symbols: RPS6KA1
Immunogen: A synthesized peptide derived from human Phospho-RPS6KA1 (T359+S363)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 1B6
Conjugate: Unconjugated
Gene: RPS6KA1
Gene Alias: 90 kDa ribosomal protein S6 kinase 1, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1), hu-1, MAP kinase-activated protein kinase 1, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1, MAPK-activated protein kinase 1a, MAPKAP kinase 1, MAPKAP kinase 1a, MAPKAPK-1, mapkapk1a, MAPKAPK-1a, p90Rsk, P90-RSK, p90-RSK 1, p90Rsk1, p90-Rsk1, p90S6K, pp90RSK1, ribosomal protein S6 kinase 2 alpha, ribosomal protein S6 kinase 2 beta, ribosomal protein S6 kinase a, polypeptide 1, ribosomal protein S6 kinase A1, ribosomal protein S6 kinase A1 L homeolog, ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase II alpha, ribosomal protein S6 kinase II beta, ribosomal protein S6 kinase polypeptide 1, ribosomal protein S6 kinase, 90kD, polypeptide 1, Ribosomal protein S6 kinase, 90kD, 1, ribosomal protein S6 kinase, 90kDa, polypeptide 1, ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog, ribosomal protein S6 kinase, polypeptide A1, ribosomal S6 kinase 1, RPS6KA, Rps6ka1, rps6ka1.L, RPS6KA1L, rsk, RSK1, Rsk-1, S6 kinase II beta, S6 protein kinase (Rsk-1), S6K-alpha 1, S6K-alpha-1, S6KII-alpha, S6KII-beta, wu:fc56h07, XELAEV_18012109mg, zgc:152654
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6195
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-RSK1 (Thr359, Ser363)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q15418
Gene Symbols:
RPS6KA1
Immunogen:
A synthesized peptide derived from human Phospho-RPS6KA1 (T359+S363)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
1B6
Conjugate:
Unconjugated
Gene:
RPS6KA1
Gene Alias:
90 kDa ribosomal protein S6 kinase 1, dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1), hu-1, MAP kinase-activated protein kinase 1, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1, MAPK-activated protein kinase 1a, MAPKAP kinase 1, MAPKAP kinase 1a, MAPKAPK-1, mapkapk1a, MAPKAPK-1a, p90Rsk, P90-RSK, p90-RSK 1, p90Rsk1, p90-Rsk1, p90S6K, pp90RSK1, ribosomal protein S6 kinase 2 alpha, ribosomal protein S6 kinase 2 beta, ribosomal protein S6 kinase a, polypeptide 1, ribosomal protein S6 kinase A1, ribosomal protein S6 kinase A1 L homeolog, ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase II alpha, ribosomal protein S6 kinase II beta, ribosomal protein S6 kinase polypeptide 1, ribosomal protein S6 kinase, 90kD, polypeptide 1, Ribosomal protein S6 kinase, 90kD, 1, ribosomal protein S6 kinase, 90kDa, polypeptide 1, ribosomal protein S6 kinase, 90kDa, polypeptide 1 L homeolog, ribosomal protein S6 kinase, polypeptide A1, ribosomal S6 kinase 1, RPS6KA, Rps6ka1, rps6ka1.L, RPS6KA1L, rsk, RSK1, Rsk-1, S6 kinase II beta, S6 protein kinase (Rsk-1), S6K-alpha 1, S6K-alpha-1, S6KII-alpha, S6KII-beta, wu:fc56h07, XELAEV_18012109mg, zgc:152654
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6195
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-AMPK alpha-2 (Thr172)
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P54646
Gene Symbols: PRKAA2
Immunogen: A synthesized peptide derived from human Phospho-PRKAA2 (Thr172)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Western Blot
Clone: 4F4
Conjugate: Unconjugated
Gene: PRKAA2
Gene Alias: 2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5563
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-AMPK alpha-2 (Thr172)
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P54646
Gene Symbols:
PRKAA2
Immunogen:
A synthesized peptide derived from human Phospho-PRKAA2 (Thr172)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Western Blot
Clone:
4F4
Conjugate:
Unconjugated
Gene:
PRKAA2
Gene Alias:
2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5563
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Antigen: Phospho-AMPK alpha-2 (Ser491)
Classification: Recombinant Monoclonal
Concentration: 1.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P54646
Gene Symbols: PRKAA2
Immunogen: A synthesized peptide derived from human Phospho-PRKAA2 (S491)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Western Blot
Clone: 3H10
Conjugate: Unconjugated
Gene: PRKAA2
Gene Alias: 2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5563
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Antigen:
Phospho-AMPK alpha-2 (Ser491)
Classification:
Recombinant Monoclonal
Concentration:
1.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P54646
Gene Symbols:
PRKAA2
Immunogen:
A synthesized peptide derived from human Phospho-PRKAA2 (S491)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Western Blot
Clone:
3H10
Conjugate:
Unconjugated
Gene:
PRKAA2
Gene Alias:
2310008I11Rik, 5'-AMP-activated protein kinase catalytic subunit alpha-2, 5'-AMP-activated protein kinase, catalytic alpha-2 chain, A830082D05, ACACA kinase, Acetyl-CoA carboxylase kinase, AMP-activated protein kinase, AMP-activated protein kinase alpha-2 subunit variant 2, AMP-activated protein kinase alpha-2 subunit variant 3, AMP-activated protein kinase alpha-2 variant B, AMPK, AMPK alpha 2, AMPK alpha-2 chain, AMPK subunit alpha-2, AMPK2, AMPKa2, AMPKalpha2, AMPK-alpha-2 chain, EC 2.7.11.1, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, PRKAA, Prkaa2, protein kinase AMP-activated catalytic subunit alpha 2, protein kinase, AMP-activated, alpha 2 catalytic subunit
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5563
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid