PIMA532590

TLR5 Recombinant Rabbit Monoclonal Antibody (JM10-88), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532590-Each-of-1 In Stock ₹ 45,646.26

PIMA532590 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

TLR5

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

O60602, Q9JLF7

Gene Symbols

TLR5

Immunogen

Recombinant protein within Human TLR5 aa 238-424

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry, Western Blot

Clone

JM10-88

Conjugate

Unconjugated

Gene

TLR5

Gene Alias

FLJ10052, MELIOS, MGC126430, MGC126431, RP11-239E10.1, SLE1, SLEB1, systemic lupus erythematosus susceptibility 1, TIL3, Tlr5, toll like receptor 5, Toll/interleukin-1 receptor-like protein 3, toll-like receptor 5

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

289337, 53791, 7100

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • TLR5 is a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents
  • TLR5 also plays a role in mediating detection of bacterial flagellins
  • TLR5 acts via MyD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response
  • TLR5 protein binds to TIRAP and MyD88 via their respective TIR domains TLR5 is highly expressed in liver, and is detected in lung and at very low levels in most other tissues
  • The TLR5 gene lies in a locus that is associated with susceptibility to Salmonella
  • Inbred strains of mice can be classified into 3 categories according to their resistance to infection with S.typhimurium: susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L) and resistant (A, CBA)
  • The strain MOLF/Ei is highly susceptible to the infection, has a unique TLR5 haplotype and a lower expression of TRL5
  • A common TLR5 stop codon polymorphism that disrupts TLR5 signaling is associated with susceptibility to Legionnaires’ disease and demonstrates the importance of TLR5 in the innate immune response.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA532590

--


Antigen:
TLR5

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
O60602, Q9JLF7

Gene Symbols:
TLR5

Immunogen:
Recombinant protein within Human TLR5 aa 238-424

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM10-88

Conjugate:
Unconjugated

Gene:
TLR5

Gene Alias:
FLJ10052, MELIOS, MGC126430, MGC126431, RP11-239E10.1, SLE1, SLEB1, systemic lupus erythematosus susceptibility 1, TIL3, Tlr5, toll like receptor 5, Toll/interleukin-1 receptor-like protein 3, toll-like receptor 5

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
289337, 53791, 7100

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532591

--


Antigen:
GBA

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P04062

Gene Symbols:
GBA

Immunogen:
Synthetic peptide within Human GBA aa 477-534

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM10-76

Conjugate:
Unconjugated

Gene:
GBA

Gene Alias:
acid beta glucosidase, acid beta-glucosidase, Alglucerase, betaGC, beta-GC, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Gba, GBA1, GBAP, GBAP1, GC, GCase, GCB, GLUC, glucocerebrosidase, glucosidase, beta, acid, glucosylceramidase, glucosylceramidase beta, glucosylceramidase beta pseudogene 1, glucosylceramidase-like protein, imiglucerase, Lysosomal acid GCase, Lysosomal acid glucosylceramidase, lysosomal glucocerebrosidase, SGTase

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
2629, 684536

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532593

--


Antigen:
Aquaporin 1

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P29972, P29975, Q02013

Gene Symbols:
Aqp1

Immunogen:
Synthetic peptide within Human AQP1 aa 245-269

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
__

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
JM10-98

Conjugate:
Unconjugated

Gene:
Aqp1

Gene Alias:
AQP 1; AQP CHIP; Aqp1; AQP-1; AQP-CHIP; aquaporin 1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); aquaporin 1 (channel-forming integral protein, 28kDa, CO blood group); aquaporin 1 (Colton blood group); aquaporin 1, Colton blood group antigen; Aquaporin CHIP; Aquaporin1; aquaporin-1; Aquaporin-CHIP; channel-like integral membrane protein, 28-kDa; CHIP 28; CHIP28; CO; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; membrane channel; MGC26324; urine water channel; Water channel protein for red blood cells and kidney proximal tubule

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11826, 25240, 358

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532596

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Antigen:
CD41

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P08514

Gene Symbols:
Itga2b

Immunogen:
Synthetic peptide within Human CD41 aa 41-74

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry, Western Blot

Clone:
JM11-19

Conjugate:
Unconjugated

Gene:
Itga2b

Gene Alias:
AI172977, alpha IIb, alphaIIb, alphaIIb protein, BDPLT16, BDPLT2, CD41, CD41B, form 1, form 2, GP IIb, GP2B, GPalpha IIb, GPIIb, GT, GTA, HPA3, integrin alpha 2b, integrin alpha 2b (Cd41b), integrin alpha-IIb, Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2, integrin subunit alpha 2b, integrin subunit alpha IIb, integrin, alpha 2B, integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41), ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb, platelet glycoprotein IIb of IIb/II Ia complex, platelet glycoprotein IIb of IIb/IIIa complex, platelet membrane glycoprotein IIb, platelet-specific antigen BAK, PPP1R93, protein phosphatase 1, regulatory subunit 93

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3674

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid