PIMA536995
Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4), FITC, Invitrogen™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA536995-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA536995 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
Phospho-PTEN (Ser380, Thr382, Thr383)
Classification
Monoclonal
Conjugate
FITC
Gene
PTEN
Gene Alias
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species
Rabbit
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
19211, 5728
Content And Storage
4° C, store in dark
Form
Liquid
Applications
Flow Cytometry
Clone
PTENS380T382383-E4
Formulation
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.
O08586, P60484
Gene Symbols
PTEN
Immunogen
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Quantity
100 Tests
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG κ
Related Products
Description
- PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency
- The PTEN gene is a phosphatidylinositol-3, 4, 5-trisphosphate 3-phosphatase
- It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases
- Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates
- PTEN negatively regulates intracellular levels of phosphatidylinositol-3, 4, 5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway
- PTEN plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation
- Also, PTEN may be a negative regulator of insulin signaling and glucose metabolism in adipose tissue
- The nuclear monoubiquitinated form possesses greater apoptotic potential, whereas the cytoplasmic nonubiquitinated form of PTEN induces less tumor suppressive ability.
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Antigen: Phospho-PTEN (Ser380, Thr382, Thr383)
Classification: Monoclonal
Conjugate: FITC
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: 4° C, store in dark
Form: Liquid
Applications: Flow Cytometry
Clone: PTENS380T382383-E4
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)
Classification:
Monoclonal
Conjugate:
FITC
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
4° C, store in dark
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PTENS380T382383-E4
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-PTEN (Ser380, Thr382, Thr383)
Classification: Monoclonal
Conjugate: APC
Gene: PTEN
Gene Alias: 10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 19211, 5728
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: PTENS380T382383-E4
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: O08586, P60484
Gene Symbols: PTEN
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-PTEN (Ser380, Thr382, Thr383)
Classification:
Monoclonal
Conjugate:
APC
Gene:
PTEN
Gene Alias:
10q23del; 2310035O07Rik; A130070J02Rik; AI463227; B430203M17Rik; BZS; CWS1; DEC; GLM2; homolog of human mutated in multiple advanced cancers; MHAM; mitochondrial phosphatase and tensin protein alpha; mitochondrial PTENalpha; Mmac; MMAC1; MMAC1 phosphatase and tensin homolog deleted on chromosome 10; mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; phosphatase and tensin homolog (mutated in multiple advanced cancers 1); phosphatase and tensin homolog deleted on chromosome ten; phosphatase and tensin-like protein; phosphatidylinositol 3; phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; phosphatidylinositol-3; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; protein tyrosine phosphatase and tensin-like protein; PTEN; pten tumor suppressor; PTEN1; TEP1
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
19211, 5728
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
PTENS380T382383-E4
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
O08586, P60484
Gene Symbols:
PTEN
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Ser380 and Thr382/383 of human phospho PTEN.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-SLP76 (Tyr128)
Classification: Monoclonal
Conjugate: Unconjugated
Gene: LCP2
Gene Alias: 76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 16822, 3937
Content And Storage: -20°C
Form: Liquid
Applications: Flow Cytometry
Clone: SLP76Y128-3F8
Formulation: PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q13094, Q60787
Gene Symbols: LCP2
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.
Quantity: 20 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-SLP76 (Tyr128)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene:
LCP2
Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
16822, 3937
Content And Storage:
-20°C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SLP76Y128-3F8
Formulation:
PBS with 0.1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q13094, Q60787
Gene Symbols:
LCP2
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.
Quantity:
20 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ
Antigen: Phospho-SLP76 (Tyr128)
Classification: Monoclonal
Conjugate: PE
Gene: LCP2
Gene Alias: 76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm
Host Species: Rabbit
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 16822, 3937
Content And Storage: 4° C
Form: Liquid
Applications: Flow Cytometry
Clone: SLP76Y128-3F8
Formulation: PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.: Q13094, Q60787
Gene Symbols: LCP2
Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.
Quantity: 100 Tests
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG κ
Antigen:
Phospho-SLP76 (Tyr128)
Classification:
Monoclonal
Conjugate:
PE
Gene:
LCP2
Gene Alias:
76 kDa tyrosine phosphoprotein; AI323664; BB161688; Lcp2; Lymphocyte cytosolic protein 2; lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa); lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD); SH2 domain-containing leukocyte protein of 76 kDa; SH2 domain-containing leukocyte protein of 76kD; SLP76; SLP-76; SLP-76 tyrosine phosphoprotein; twm
Host Species:
Rabbit
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
16822, 3937
Content And Storage:
4° C
Form:
Liquid
Applications:
Flow Cytometry
Clone:
SLP76Y128-3F8
Formulation:
PBS with 0.20% BSA and 0.09% sodium azide
Gene Accession No.:
Q13094, Q60787
Gene Symbols:
LCP2
Immunogen:
A synthetic phospho-peptide corresponding to residues surrounding Tyr128 of human phospho SLP-76.
Quantity:
100 Tests
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG κ