PIMA537897
NLK Recombinant Rabbit Monoclonal Antibody (ARC2441), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA537897-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA537897 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
NLK
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
D3ZSZ3, O54949, Q9UBE8
Gene Symbols
NLK
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human NLK (NP_0573153)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
ARC2441
Conjugate
Unconjugated
Gene
NLK
Gene Alias
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18099, 497961, 51701
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive Samples: HeLa, SW480, Mouse brain, Rat brain Immunogen sequence: AVHLLCRMLV FDPSKRISAK DALAHPYLDE GRLRYHTCMC KCCFSTSTGR VYTSDFEPVT NPKFDDTFEK NLSSVRQVKE IIHQFILEQQ KGNRVPLCIN P NLK is a serine/threonine kinase involved in signal transduction and cellular communication
- Positive effector of the non-canonical Wnt signaling pathway, acting downstream of WNT5A, MAP3K7/TAK1 and HIPK2
- Activation of this pathway causes binding to and phosphorylation of the histone methyltransferase SETDB1
- The NLK-SETDB1 complex subsequently interacts with PPARG, leading to methylation of PPARG target promoters at histone H3K9 and transcriptional silencing
- The resulting loss of PPARG target gene transcription inhibits adipogenesis and promotes osteoblastogenesis in mesenchymal stem cells (MSCs)
- Negative regulator of the canonical Wnt/beta-catenin signaling pathway
- Binds to and phosphorylates TCF7L2/TCF4 and LEF1, promoting the dissociation of the TCF7L2/LEF1/beta-catenin complex from DNA, as well as the ubiquitination and subsequent proteolysis of LEF1
- Together these effects inhibit the transcriptional activation of canonical Wnt/beta-catenin target genes
- Negative regulator of the Notch signaling pathway
- Binds to and phosphorylates NOTCH1, thereby preventing the formation of a transcriptionally active ternary complex of NOTCH1, RBPJ/RBPSUH and MAML1
- Negative regulator of the MYB family of transcription factors.
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Antigen: NLK
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: D3ZSZ3, O54949, Q9UBE8
Gene Symbols: NLK
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human NLK (NP_0573153)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC2441
Conjugate: Unconjugated
Gene: NLK
Gene Alias: AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18099, 497961, 51701
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NLK
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
D3ZSZ3, O54949, Q9UBE8
Gene Symbols:
NLK
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human NLK (NP_0573153)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC2441
Conjugate:
Unconjugated
Gene:
NLK
Gene Alias:
AI194375; LAK1; nemo like kinase; nemo-like kinase; NLK; Protein LAK1; RGD1561602; serine/threonine protein kinase NLK; serine/threonine-protein kinase NLK
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18099, 497961, 51701
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NUP62
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P17955, P37198, Q63850
Gene Symbols: Nup62
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 423-522 of human NUP62 (P37198)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Clone: ARC2444
Conjugate: Unconjugated
Gene: Nup62
Gene Alias: 62 kDa nucleoporin; AA589433; AI426861; AI790512; AU045898; D7Ertd649e; DKFZp547L134; FLJ20822; FLJ43869; IBSN; MGC841; Np62; nuclear pore complex 1; nuclear pore glycoprotein 62; nuclear pore glycoprotein p62; nucleoporin 62; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin Nup62; nucleoporin p62; Nup62; Nupc1; p62; SNDI
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18226, 23636, 65274
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NUP62
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P17955, P37198, Q63850
Gene Symbols:
Nup62
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 423-522 of human NUP62 (P37198)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Clone:
ARC2444
Conjugate:
Unconjugated
Gene:
Nup62
Gene Alias:
62 kDa nucleoporin; AA589433; AI426861; AI790512; AU045898; D7Ertd649e; DKFZp547L134; FLJ20822; FLJ43869; IBSN; MGC841; Np62; nuclear pore complex 1; nuclear pore glycoprotein 62; nuclear pore glycoprotein p62; nucleoporin 62; nucleoporin 62kD; nucleoporin 62kDa; nucleoporin Nup62; nucleoporin p62; Nup62; Nupc1; p62; SNDI
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18226, 23636, 65274
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: MAT2A
Classification: Recombinant Monoclonal
Concentration: 0.6 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P18298, P31153, Q3THS6
Gene Symbols: MAT2A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAT2A (P31153)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC2447
Conjugate: Unconjugated
Gene: MAT2A
Gene Alias: adoMet synthase 2; adoMet synthetase 2; AMS2; D630045P18Rik; MAT 2; MAT2A; MATA2; MATII; MAT-II; Methionine adenosyltransferase 2; methionine adenosyltransferase 2A; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; non-hepatic-type S-adenosylmethionine synthetase; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; Sams2; testicular tissue protein Li 121
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 171347, 232087, 4144
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MAT2A
Classification:
Recombinant Monoclonal
Concentration:
0.6 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P18298, P31153, Q3THS6
Gene Symbols:
MAT2A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAT2A (P31153)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC2447
Conjugate:
Unconjugated
Gene:
MAT2A
Gene Alias:
adoMet synthase 2; adoMet synthetase 2; AMS2; D630045P18Rik; MAT 2; MAT2A; MATA2; MATII; MAT-II; Methionine adenosyltransferase 2; methionine adenosyltransferase 2A; Methionine adenosyltransferase II; methionine adenosyltransferase II, alpha; non-hepatic-type S-adenosylmethionine synthetase; S-adenosylmethionine synthase; S-adenosylmethionine synthase isoform type-2; S-adenosylmethionine synthetase isoform type-2; Sams2; testicular tissue protein Li 121
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
171347, 232087, 4144
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PAG1
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q3U1F9, Q9JM80, Q9NWQ8
Gene Symbols: PAG1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 333-432 of human PAG1 (Q9NWQ8)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC2448
Conjugate: Unconjugated
Gene: PAG1
Gene Alias: CBP; Csk binding protein; csk-binding protein; F730007C19Rik; Pag; PAG 1; Pag1; PAG1B; phosphoprotein associated with glycosphingolipid microdomains 1; phosphoprotein associated with glycosphingolipid-enriched microdomains 1; phosphoprotein membrane anchor with glycosphingolipid microdomains 1; phosphoprotein transmembrane adaptor 1; phosphoprotein-associated with GEMs; pregnancy-associated glycoprotein 1; Pregnancy-specific protein B; PSP-B; similar to pregnancy-associated glycoprotein 1; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; transmembrane phosphoprotein Cbp
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 55824, 64019, 94212
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PAG1
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q3U1F9, Q9JM80, Q9NWQ8
Gene Symbols:
PAG1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 333-432 of human PAG1 (Q9NWQ8)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC2448
Conjugate:
Unconjugated
Gene:
PAG1
Gene Alias:
CBP; Csk binding protein; csk-binding protein; F730007C19Rik; Pag; PAG 1; Pag1; PAG1B; phosphoprotein associated with glycosphingolipid microdomains 1; phosphoprotein associated with glycosphingolipid-enriched microdomains 1; phosphoprotein membrane anchor with glycosphingolipid microdomains 1; phosphoprotein transmembrane adaptor 1; phosphoprotein-associated with GEMs; pregnancy-associated glycoprotein 1; Pregnancy-specific protein B; PSP-B; similar to pregnancy-associated glycoprotein 1; transmembrane adapter protein PAG; transmembrane adaptor protein PAG; transmembrane phosphoprotein Cbp
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
55824, 64019, 94212
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid