PIMA538076
MELK Recombinant Rabbit Monoclonal Antibody (ARC2032), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA538076-Each-of-1 | In Stock | ₹ 46,501.86 |
PIMA538076 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,501.86
GST (18%): ₹ 8,370.335
Total Price: ₹ 54,872.195
Antigen
MELK
Classification
Recombinant Monoclonal
Concentration
0.55 mg/mL
Formulation
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q14680, Q61846
Gene Symbols
MELK
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MELK (NP_0556061)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Clone
ARC2032
Conjugate
Unconjugated
Gene
MELK
Gene Alias
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17279, 362510, 9833
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Positive Samples: 293T, Jurkat, K-562, Mouse testis, Rat testis Immunogen sequence: MKDYDELLKY YELHETIGTG GFAKVKLACH ILTGEMVAIK IMDKNTLGSD LPRIKTEIEA LKNLRHQHIC QLYHVLETAN KIFMVLEYCP GGELFDYIIS MELK is a serine/threonione kinase which is related to the AMPK family that has been linked to the cell cycle
- MELK has also been shown to be overexpressed in cancer and has been identified has a potential target for cancer therapeutics
- MELK has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622
- Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1
- Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis
- Plays a key role in cell proliferation and carcinogenesis
- Required for proliferation of embryonic and postnatal multipotent neural progenitors
- Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14
- Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus
- May also play a role in primitive hematopoiesis.
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Antigen: MELK
Classification: Recombinant Monoclonal
Concentration: 0.55 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q14680, Q61846
Gene Symbols: MELK
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MELK (NP_0556061)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Clone: ARC2032
Conjugate: Unconjugated
Gene: MELK
Gene Alias: AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17279, 362510, 9833
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
MELK
Classification:
Recombinant Monoclonal
Concentration:
0.55 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q14680, Q61846
Gene Symbols:
MELK
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MELK (NP_0556061)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Clone:
ARC2032
Conjugate:
Unconjugated
Gene:
MELK
Gene Alias:
AI327312; hMELK; HPK38; Kiaa0175; Maternal embryonic leucine zipper kinase; Melk; mKIAA0175; MPK38; OTTHUMP00000046113; pEg3 kinase; Pk38; Protein kinase Eg3; protein kinase PK38; RP11-8N6.1; Tyrosine-protein kinase MELK
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17279, 362510, 9833
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: NEK6
Classification: Recombinant Monoclonal
Concentration: 0.57 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P59895, Q9ES70, Q9HC98
Gene Symbols: NEK6
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human NEK6 (Q9HC98)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC2034
Conjugate: Unconjugated
Gene: NEK6
Gene Alias: 1300007C09Rik; Nek6; Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related expressed kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA related kinase 6; NIMA-related expressed kinase 6; NIMA-related kinase 6; nimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; serine/threonine-protein kinase Nek6; SID; SID6-1512
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10783, 360161, 59126
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
NEK6
Classification:
Recombinant Monoclonal
Concentration:
0.57 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P59895, Q9ES70, Q9HC98
Gene Symbols:
NEK6
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human NEK6 (Q9HC98)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC2034
Conjugate:
Unconjugated
Gene:
NEK6
Gene Alias:
1300007C09Rik; Nek6; Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related expressed kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA related kinase 6; NIMA-related expressed kinase 6; NIMA-related kinase 6; nimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; serine/threonine-protein kinase Nek6; SID; SID6-1512
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10783, 360161, 59126
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: VAV2
Classification: Recombinant Monoclonal
Concentration: 0.17 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P52735, Q60992
Gene Symbols: Vav2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VAV2 (P52735)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC2041
Conjugate: Unconjugated
Gene: Vav2
Gene Alias: 2810040F13Rik; AI847175; Guanine nucleotide exchange factor VAV2; Oncogene VAV2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; vav guanine nucleotide exchange factor 2; VAV2; VAV-2; Vav2 oncogene
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22325, 7410
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
VAV2
Classification:
Recombinant Monoclonal
Concentration:
0.17 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P52735, Q60992
Gene Symbols:
Vav2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VAV2 (P52735)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC2041
Conjugate:
Unconjugated
Gene:
Vav2
Gene Alias:
2810040F13Rik; AI847175; Guanine nucleotide exchange factor VAV2; Oncogene VAV2; vav 2 guanine nucleotide exchange factor; vav 2 oncogene; vav guanine nucleotide exchange factor 2; VAV2; VAV-2; Vav2 oncogene
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22325, 7410
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: ATF5
Classification: Recombinant Monoclonal
Concentration: 0.65 mg/mL
Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: O70191, Q6P788, Q9Y2D1
Gene Symbols: Atf5
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 183-282 of human ATF5 (Q9Y2D1)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: ARC2043
Conjugate: Unconjugated
Gene: Atf5
Gene Alias: activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 107503, 22809, 282840
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
ATF5
Classification:
Recombinant Monoclonal
Concentration:
0.65 mg/mL
Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
O70191, Q6P788, Q9Y2D1
Gene Symbols:
Atf5
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 183-282 of human ATF5 (Q9Y2D1)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
ARC2043
Conjugate:
Unconjugated
Gene:
Atf5
Gene Alias:
activating transcription factor 5; Activating transcription factor 5-alpha/beta; activating transcription factor 7; activating transcription factor X; AFTA; ATF5; Atf7; Atfx; BZIP protein ATF7; cAMP-dependent transcription factor ATF-5; Cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; NAP1; NRIF3-associated protein; ODA-10; Transcription factor ATFx; transcription factor-like protein ODA-10
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
107503, 22809, 282840
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid