PIMA542812

TBK1 Recombinant Rabbit Monoclonal Antibody (4G6C7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542812-Each-of-1 In Stock ₹ 44,020.62

PIMA542812 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

TBK1

Classification

Recombinant Monoclonal

Concentration

1.5 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q9UHD2, Q9WUN2

Gene Symbols

TBK1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBK1/NAK (Q9UHD2).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

4G6C7

Conjugate

Unconjugated

Gene

TBK1

Gene Alias

1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

29110, 299827, 56480

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive test controls include: Mouse lung, Mouse testis, Rat testis, 293T, HepG2
  • The target is usually found in the following locations: Cytoplasm
  • Immunogen sequence: MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLFAIKVF NNISFLRPVD VQMREFEVLK KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE TBK1 serine/threonine kinase is a member of the IKK family and is involved in NF-kappa B activation and IRF3 signaling
  • TBK1 is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses
  • NF-KB mediates the expression of a great variety of genes in response to extracellular stimuli
  • NF-KB is associated with IKB proteins in the cell cytoplasm, which inhibit NF-KB activity
  • Phosphorylation of I-KB by IKB kinase (IKK) complex leads to degradation of I-KB and activation of NF-KB
  • The IKK complex contains IKKa, IKK beta, and IKKK
  • A novel IKK related kinase was recently identified and designated TBK1 (TANK-binding kinase 1), NAK (NF-KB-activating kinase), and T2K
  • NAK/TBK1 activates IKK beta through direct phosphorylation
  • NAK/TBK1 is activated by growth factors and PMA and mediates IKK and NF-kB activation in response to growth factors
  • NAK/TBK1 functions upstream of NIK and the IKK complex
  • NAK/TBK1 is also critical in protecting embryonic liver from apoptosis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA542812

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Antigen:
TBK1

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9UHD2, Q9WUN2

Gene Symbols:
TBK1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TBK1/NAK (Q9UHD2).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4G6C7

Conjugate:
Unconjugated

Gene:
TBK1

Gene Alias:
1200008B05Rik; AI462036; AW048562; FLJ11330; FTDALS4; NAK; NF-kappa-B-activating kinase; NF-kB-activating kinase; serine/threonine protein kinase TBK1; serine/threonine-protein kinase TBK1; T2K; TANK binding kinase 1; TANK-binding kinase 1; tbk; TBK1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
29110, 299827, 56480

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542813

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Antigen:
SLIT2

Classification:
Recombinant Monoclonal

Concentration:
1.9 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
O94813, Q9R1B9, Q9WVC1

Gene Symbols:
SLIT2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human Slit2 (O94813).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1T5A3

Conjugate:
Unconjugated

Gene:
SLIT2

Gene Alias:
downregulated during adipocyte differentiation-1; Drad-1; E030015M03Rik; E130320P19Rik; mKIAA4141; neurogenic extracellular slit protein; SLIL3; Slit; slit guidance ligand 2; slit homolog 2 (Drosophila); slit homolog 2 protein; Slit homolog 2 protein C-product; Slit homolog 2 protein N-product; SLIT2; Slit-2; Slit2 protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20563, 360272, 9353

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542814

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Antigen:
EHD1

Classification:
Recombinant Monoclonal

Concentration:
1.28 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q641Z6, Q9H4M9, Q9WVK4

Gene Symbols:
EHD1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human EHD1 (Q9H4M9).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
5S4P9

Conjugate:
Unconjugated

Gene:
EHD1

Gene Alias:
AA409636; CDABP0131; EH domain containing 1; EH domain-containing protein 1; Ehd1; EH-domain containing 1; H-PAST; HPAST1; mPAST1; PAST; PAST homolog 1; PAST1; RGD1306960; RME-1; testilin

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10938, 13660, 293692

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542815

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Antigen:
CRMP5

Classification:
Recombinant Monoclonal

Concentration:
0.15 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9BPU6, Q9EQF6, Q9JHU0

Gene Symbols:
DPYSL5

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 465-564 of human CRMP5/DPYSL5 (Q9BPU6).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
5L4S8

Conjugate:
Unconjugated

Gene:
DPYSL5

Gene Alias:
collapsin response mediator protein 5; collapsin response mediator protein-5; CRAM; CRMP3-associated molecule; Crmp5; CRMP-5; dihydropyrimidinase like 5; dihydropyrimidinase-like 5; dihydropyrimidinase-related protein 5; Dpysl5; DRP-5; Ulip6; ULIP-6; ULIP6 protein; UNC33-like phosphoprotein 6

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56896, 65208, 65254

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid