PIMA538059

PAK3 Recombinant Rabbit Monoclonal Antibody (ARC1955), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA538059-Each-of-1 In Stock ₹ 47,870.82

PIMA538059 - Each of 1

₹ 47,870.82

In Stock

Quantity

1

Base Price: ₹ 47,870.82

GST (18%): ₹ 8,616.748

Total Price: ₹ 56,487.568

Antigen

PAK3

Classification

Recombinant Monoclonal

Concentration

0.58 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q61036, Q62829

Gene Symbols

PAK3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (O75914)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

ARC1955

Conjugate

Unconjugated

Gene

PAK3

Gene Alias

2.7.11.1; adriamycin resistance-associated; ARA; beta-PAK; bPAK; CDC42/RAC effector kinase PAK-B; CDKN1A; hPAK3; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p21-activated kinase 3; p65-PAK; PAK beta; Pak3; Pak-3; PAK3beta; Pak65alpha; Pak65beta; Pakb; Serine/threonine-protein kinase PAK 3; Stk4

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18481, 29433

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive Samples: SH-SY5Y, Mouse brain, Rat brain Immunogen sequence: MSDGLDNEEK PPAPPLRMNS NNRDSSALNH SSKPLPMAPE EKNKKARLRS IFPGGGDKTN KKKEKERPEI SLPSDFEHTI HVGFDAVTGE FTPDLYGSQM PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
  • PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities
  • The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation
  • There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation
  • Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.

Compare Similar Items

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Thermo Scientific

PIMA538059

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Antigen:
PAK3

Classification:
Recombinant Monoclonal

Concentration:
0.58 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q61036, Q62829

Gene Symbols:
PAK3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PAK3 (O75914)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC1955

Conjugate:
Unconjugated

Gene:
PAK3

Gene Alias:
2.7.11.1; adriamycin resistance-associated; ARA; beta-PAK; bPAK; CDC42/RAC effector kinase PAK-B; CDKN1A; hPAK3; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p21-activated kinase 3; p65-PAK; PAK beta; Pak3; Pak-3; PAK3beta; Pak65alpha; Pak65beta; Pakb; Serine/threonine-protein kinase PAK 3; Stk4

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18481, 29433

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Thermo Scientific

PIMA538063

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Antigen:
4-1BB Ligand

Classification:
Recombinant Monoclonal

Concentration:
0.98 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P41273, P41274

Gene Symbols:
TNFSF9

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 155-254 of human 4-1BBL/CD137L (P41273)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1963

Conjugate:
Unconjugated

Gene:
TNFSF9

Gene Alias:
4 1 BB Ligand; 4 1 BBL; 41BB Ligand; 4-1BB ligand; 41BBL; 4-1BBL; 4-1BB-L; AI848817; CD 137 Ligand; CD 137L; CD137 Ligand; CD137L; Cd157l; CDw137L; costimulatory molecule; homolog of mouse 4-1BB-L; Ly63l; receptor 4-1BB ligand; TNFRSF9; Tnfsf9; TNLG5A; tumor necrosis factor (ligand) superfamily member 9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand 5A; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor superfamily member 9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21950, 353218, 8744

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538064

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Antigen:
MYST1

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9D1P2, Q9H7Z6

Gene Symbols:
KAT8

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-458 of human KAT8/MYST1/MOF (Q9H7Z6)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
ARC1964

Conjugate:
Unconjugated

Gene:
KAT8

Gene Alias:
2010203C02Rik; 5830450F21Rik; D7Ertd629e; h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase Myst1; hMOF; K (lysine) acetyltransferase 8; K(lysine) acetyltransferase 8; Kat8; Lysine acetyltransferase 8; MOF; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1; MYST1; MYST-1; ortholog of Drosophila males absent on the first (MOF); PP7073; probable histone acetyltransferase MYST1; ZC2HC8

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
67773, 84148

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA538065

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Antigen:
SNX1

Classification:
Recombinant Monoclonal

Concentration:
0.63 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q13596

Gene Symbols:
SNX1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SNX1 (Q13596)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Clone:
ARC1969

Conjugate:
Unconjugated

Gene:
SNX1

Gene Alias:
HsT17379; MGC8664; Snx1; SNX1A; sorting nexin 1; sorting nexin 1A; sorting nexin-1; VPS5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6642

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid